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    • DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival 

      Pedersen, Christine Aaserød; Cao, Maria Dung; Fleischer, Thomas; Rye, Morten Beck; Knappskog, Stian; Eikesdal, Hans Petter; Lønning, Per Eystein; Tost, Jörg; Kristensen, Vessela N.; Tessem, May-Britt; Giskeødegård, Guro F.; Bathen, Tone Frost (Peer reviewed; Journal article, 2022)
      Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ...
    • Possible strategies for use of artificial intelligence in screen-reading of mammograms, based on retrospective data from 122,969 screening examinations 

      Larsen, Marthe; Aglen, Camilla Flåt; Hoff, Solveig Roth; Lund-Hanssen, Håkon; Hofvind, Solveig Sand-Hanssen (Peer reviewed; Journal article, 2022)
      Objectives Artificial intelligence (AI) has shown promising results when used on retrospective data from mammographic screening. However, few studies have explored the possible consequences of different strategies for ...
    • Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases 

      Habberstad, Ragnhild H; Aass, Nina Kathrine; Mollnes, Tom Eirik; Damås, Jan Kristian; Brunelli, Cinzia; Rossi, Romina; Garcia-Alonso, Elena; Kaasa, Stein; Klepstad, Pål (Peer reviewed; Journal article, 2022)
      Context Inflammation is proposed to influence tumor response in radiotherapy (RT). Clinical studies to investigate the relationship between inflammatory markers and RT response is warranted to understand the variable RT ...
    • Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia 

      Watts, Eleanor L.; Perez-Cornago, Aurora; Fensom, Georgina K.; Smith-Byrne, Karl; Noor, Urwah; Andrews, Colm D.; Gunter, Marc J.; Holmes, Michael V.; Martin, Richard M.; Tsilidis, Konstantinos K.; Albanes, Demetrius; Barricarte, Aurelio; Bueno-de-Mesquita, Bas; Chen, Chu; Cohn, Barbara A.; Dimou, Niki L.; Ferrucci, Luigi; Flicker, Leon; Freedman, Neal D.; Giles, Graham G.; Giovannucci, Edward L.; Goodman, Gary E.; Haiman, Christopher A.; Hankey, Graeme J.; Huang, Jiaqi; Huang, Wen-Yi; Hurwitz, Lauren M.; Kaaks, Rudolf; Knekt, Paul; Kubo, Tatsuhiko; Langseth, Hilde; Laughlin, Gail; Le Marchand, Loic; Luostarinen, Tapio; MacInnis, Robert J.; Mäenpää, Hanna O.; Männistö, Satu; Metter, E. Jeffrey; Mikami, Kazuya; Mucci, Lorelei A.; Olsen, Anja; Ozasa, Kotaro; Palli, Domenico; Penney, Kathryn L.; Platz, Elizabeth A.; Rissanen, Harri; Sawada, Norie; Schenk, Jeannette M.; Stattin, Pär; Tamakoshi, Akiko; Thysell, Elin; Tsai, Chiaojung Jillian; Tsugane, Shoichiro; Vatten, Lars Johan; Weiderpass, Elisabete; Weinstein, Stephanie J.; Wilkens, Lynne R.; Yeap, Bu B.; Allen, Naomi E.; Key, Timothy J.; Travis, Ruth C. (Peer reviewed; Journal article, 2022)
      Previous studies had limited power to assess the associations of testosterone with aggressive disease as a primary endpoint. Further, the association of genetically predicted testosterone with aggressive disease is not ...
    • The short-term effect of a modified comprehensive geriatric assessment and regularly case conferencing on neuropsychiatric symptoms in nursing homes: a cluster randomized trial 

      Stensvik, Geir-Tore; Helvik, Anne-Sofie; Haugan, Gørill; Steinsbekk, Aslak; Salvesen, Øyvind; Nakrem, Sigrid (Peer reviewed; Journal article, 2022)
      Aims To investigate the short-term effect of implementing a modified comprehensive geriatric assessment and regularly case conferencing in nursing homes on neuropsychiatric symptoms. Background Neuropsychiatric symptoms ...
    • Health-related quality of life in young adults born small for gestational age: a prospective cohort study 

      Mehl, Cathrin Vano; Hollund, Ingrid Marie Husby; Iversen, Johanne Marie; Lydersen, Stian; Mork, Paul Jarle; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2022)
      Background Individuals born small for gestational age (SGA) have an increased risk of several adverse health outcomes, but their health-related quality of life (HRQoL) across young adulthood has yet to be studied. The ...
    • Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects 

      Howe, Laurence J.; Nivard, Michel G.; Morris, Tim T.; Hansen, Ailin Falkmo; Rasheed, Humaira; Cho, Yoonsu; Chittoor, Geetha; Ahlskog, Rafael; Lind, Penelope A.; Palviainen, Teemu; van der Zee, Matthijs D.; Cheesman, Rosa Catherine Gillespie; Mangino, Massimo; Wang, Yunzhang; Li, Shuai; Klaric, Lucija; Ratliff, Scott M.; Bielak, Lawrence F.; Nygaard, Marianne; Giannelis, Alexandros; Willoughby, Emily A.; Reynolds, Chandra A.; Balbona, Jared V.; Andreassen, Ole; Ask, Helga; Baras, Aris; Bauer, Christopher R.; Boomsma, Dorret I.; Campbell, Archie; Campbell, Harry; Chen, Zhengming; Christofidou, Paraskevi; Corfield, Elizabeth Claire; Dahm, Christina C.; Dokuru, Deepika R.; Evans, Luke M.; de Geus, Eco J. C.; Giddaluru, Sudheer; Gordon, Scott D.; Harden, K. Paige; Hill, W. David; Hughes, Amanda; Kerr, Shona M.; Kim, Yongkang; Kweon, Hyeokmoon; Latvala, Antti; Lawlor, Deborah A.; Li, Liming; Lin, Kuang; Magnus, Per Minor; Magnusson, Patrik K. E.; Mallard, Travis T.; Martikainen, Pekka; Mills, Melinda C.; Njølstad, Pål Rasmus; Overton, John D.; Pedersen, Nancy L.; Porteous, David J.; Reid, Jeffrey; Silventoinen, Karri; Southey, Melissa C.; Stoltenberg, Camilla; Tucker-Drob, Elliot M.; Wright, Margaret J.; Kweon, Hyeokmoon; Koellinger, Philipp D.; Benjamin, Daniel J.; Turley, Patrick; Howe, Laurence J.; Nivard, Michel G.; Morris, Tim T.; Plomin, Robert; Havdahl, Alexandra; Bartels, Meike; Martin, Nicholas G.; Oskarsson, Sven; Justice, Anne E.; Millwood, Iona Y.; Hveem, Kristian; Willer, Cristen J.; Åsvold, Bjørn Olav; Kaprio, Jaakko; Medland, Sarah E.; Walters, Robin G.; Evans, David M.; Smith, George Davey; Hayward, Caroline; Brumpton, Ben; Hemani, Gibran; Davies, Neil Martin; Hewitt, John K.; Keller, Matthew C.; Stallings, Michael C.; Lee, James J.; Christensen, Kaare; Kardia, Sharon L. R.; Peyser, Patricia A.; Smith, Jennifer A.; Wilson, James F.; Hopper, John L.; Hägg, Sara; Spector, Tim D.; Pingault, Jean-Baptiste; Næss, Øyvind Erik; Davey Smith, George; Brumpton, Ben Michael (Peer reviewed; Journal article, 2022)
      Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives (indirect ...
    • Status of vitamin A among overweight/obese pregnant women: relation to pregnancy complications, birth weight, and metabolic measures 

      Kinge, Ingvild Tapio (Master thesis, 2022)
      Den globale prevalensen av vitamin A-mangel og -insuffisiens er høy, og er en av de store årsakene til morbiditet og mortalitet blant barn og gravide, særlig i lavinntektsland. Nyere studier har funnet en sammenheng mellom ...
    • Antibiotic use in children before, during and after hospitalisation 

      Thaulow, Christian Magnus; Blix, Hege Salvesen; Nilsen, Roy Miodini; Eriksen, Beate Horsberg; Wathne, Jannicke Slettli; Berild, Dag; Harthug, Stig (Peer reviewed; Journal article, 2022)
      Purpose To investigate ambulatory antibiotic use in children during 1 year before and 1 year after in-hospital antibiotic exposure compared to children from the general population that had not received antibiotics in-hospital. ...
    • Hydration Status During Commercial Saturation Diving Measured by Bioimpedance and Urine Specific Gravity 

      Wekre, Stian Lande; Landsverk, Halvor Dagssøn; Lautridou, Jacky Jean Joseph; Hjelde, Astrid; Imbert, Jean Pierre; Balestra, Costantino; Eftedal, Ingrid (Peer reviewed; Journal article, 2022)
      Excessive fluid loss triggered by hyperbaric pressure, water immersion and hot water suits causes saturation divers to be at risk of dehydration. Dehydration is associated with reductions in mental and physical performance, ...
    • Cohort Profile Update: The HUNT Study, Norway 

      Åsvold, Bjørn Olav; Langhammer, Arnulf; Rehn, Tommy Aune; Kjelvik, Grete; Grøntvedt, Trond Viggo; Sørgjerd, Elin Pettersen; Fenstad, Jørn; Heggland, Jon; Holmen, Oddgeir; Stuifbergen, Maria C; Vikjord, Sigrid Anna Aalberg; Brumpton, Ben Michael; Skjellegrind, Håvard; Thingstad, Pernille; Sund, Erik; Selbæk, Geir; Mork, Paul Jarle; Rangul, Vegar; Hveem, Kristian; Næss, Marit; Krokstad, Steinar (Peer reviewed; Journal article, 2022)
    • Quality of care for peripheral intravenous catheters (PIVCs) in Nepal: A cross-sectional study on feasibility and inter-rater agreement of the Peripheral Intravenous Catheters-mini Questionnaire (PIVC-miniQ) in a tertiary care hospital 

      Shrestha, Sulekha; Vieler, Johannes; Haug, Nikolai Juliussen; Afset, Jan Egil; Høvik, Lise Husby; Lydersen, Stian; Gustad, Lise Tuset (Peer reviewed; Journal article, 2021)
      Objectives There is a lack of data regarding the quality of peripheral intravenous catheter (PIVC)-related care from low-income and middle-income countries, even though the use of PIVCs may lead to local or severe systemic ...
    • A quality assurance project for acute appendicitis at St. Olavs University Hospital from 2007 to 2021 

      Skåre, Silje Eckell; Lødeng, Ina Uglum (Master thesis, 2022)
      Bakgrunn og mål: Akutt appendisitt (AA) er en av de vanligste årsakene til akutt abdomen med behov for rask kirurgi. Diagnostisering av AA kan være krevende, og håndteringen av tilstanden varierer. Målet med denne retrospektive ...
    • Pasienter med mistenkt synkope i akuttmottaket En deskriptiv studie med fokus på utredning av pasienter med mistenkt synkope i akuttmottaket ved St. Olavs Hospital i Trondheim 

      Skaga, Siri (Master thesis, 2022)
      Bakgrunn Synkope defineres som “et raskt inntreffende, forbigående bevissthetstap med kort varighet og spontan tilbakevending til normaltilstand". Pasienter med mistenkt synkope utgjør en betydelig andel av pasienter som ...
    • Plasma levels of fibroblast growth factor 23 in pregnant Norwegian women and relation with adverse pregnancy outcomes 

      Nesland, Lars Andreas Haga (Master thesis, 2022)
      Bakgrunn: Fibroblast vekstfaktor 23 (FGF23) syntetiseres hovedsakelig i osteocytter. Det regulerer nivåene av fosfat og vitamin D. Placenta uttrykker både reseptoren og ko-reseptoren til FGF23, samt gener som er kjente mål ...
    • Vitamin D status among overweight/obese pregnant women: associations with pregnancy complications, birth weight and metabolic parameters 

      Øvreseth, Anna Hundere (Master thesis, 2022)
      Sammendrag Bakgrunn: Det er en høy prevalens av vitamin D-mangel globalt, både hos gravide og ikke-gravide. Overvektige har lavere nivå av vitamin D enn slanke. Vitamin D stimulerer kalsiumabsorbsjon i tarmen, og er viktig ...
    • Fra ventested til utredende enhet - Effekten av organisatoriske tiltak for bedre pasienthåndtering i Akutten ved St. Olavs hospital 

      Aanesland, Even (Master thesis, 2022)
      SAMMENDRAG Bakgrunn: Akutten ved St. Olavs hospital igangsatte fra 2018 flere tiltak for å motvirke opphopning av pasienter og forbedre pasientsikkerheten. Hensikten men denne studien var å kartlegge hvordan pasientflyt- ...
    • Outcomes after Trochleoplasty. 

      Høigaard, Maria L; Hortemo, Grete Sofie; Rosendahl, Karen; Drogset, Jon Olav (Master thesis, 2022)
      FORMÅL: Formålet med studien var å utføre en litteraturstudie vedrørende resultater etter trochleaplastikk. METODER: Vi utførte et litteratursøk i Medline, på publikasjoner som omhandlet trochleaplastikk, i engelskspråklige ...
    • A study of Glasgow Prognostic Score (GPS) and change in Health-Related Quality of Life (HRQoL) in advanced non-small cell lung cancer (NSCLC) 

      Oliversen, Ole Aleksander Skaug (Master thesis, 2022)
      Sammendrag Bakgrunn Lungekreft er en dødelig sykdom assosiert med høy grad av systemisk inflammasjon. Glasgow Prognostic Score (GPS) er basert på albumin og C-reaktivt protein (CRP). GPS er en prognostisk faktor for ...