Blar i Fakultet for medisin og helsevitenskap (MH) på dokumenttype "Peer reviewed"

Viser treff 1-20 av 7643

    • 1-year follow-up of 920 hip and knee arthroplasty patients after implementing fast-track: Good outcomes in a Norwegian university hospital 

      Winther, Siri Bjørgen; Foss, Olav A.; Wik, Tina Strømdal; Davis, Shawn Patric; Engdal, Monika; Jessen, Vigleik; Husby, Otto Schnell (Journal article; Peer reviewed, 2015)
      Background — Fast–track has become a well–known concept resulting in improved patient satisfaction and postoperative results. Concerns have been raised about whether increased efficiency could compromise safety, and whether ...

    • 18F-FACBC PET/MRI in diagnostic assessment and neurosurgery of gliomas 

      Karlberg, Anna Maria; Berntsen, Erik Magnus; Johansen, Håkon; Skjulsvik, Anne Jarstein; Reinertsen, Ingerid; Hong, Yan Dai; Xiao, Yiming; Rivaz, Hassan; Borghammer, Per; Solheim, Ole; Eikenes, Live (Journal article; Peer reviewed, 2019)
      Purpose This pilot study aimed to evaluate the amino acid tracer 18F-FACBC with simultaneous PET/MRI in diagnostic assessment and neurosurgery of gliomas. Materials and Methods Eleven patients with suspected primary or ...

    • 18F-FACBC PET/MRI in the evaluation of human brain metastases: a case report 

      Johannessen, Knut; Berntsen, Erik Magnus; Johansen, Håkon; Solheim, Tora S; Karlberg, Anna Maria; Eikenes, Live (Peer reviewed; Journal article, 2021)
      Abstract Background: Patients with metastatic cancer to the brain have a poor prognosis. In clinical practice, MRI is used to delineate, diagnose and plan treatment of brain metastases. However, MRI alone is limited in ...

    • 18F-Fluciclovine PET/MRI for preoperative lymph node staging in high-risk prostate cancer patients 

      Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Willoch, Frode; Størkersen, Øystein; Sandsmark, Elise; Moestue, Siver Andreas; Tessem, May-Britt; Halvorsen, Dag; Kjøbli, Eirik; Angelsen, Anders; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)
      Objective To investigate the diagnostic potential of simultaneous 18F-fluciclovine PET/MRI for pelvic lymph node (LN) staging in patients with high-risk prostate cancer. Methods High-risk prostate cancer patients (n=28) ...

    • 1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans 

      Sønderby, Ida Elken; van der Meer, Dennis; Moreau, Clara; Kaufmann, Tobias; Walters, G. Bragi; Ellegaard, Maria; Abdellaoui, Abdel; Ames, David; Amunts, Katrin; Andersson, Micael; Armstrong, Nicola J.; Bernard, Manon; Blackburn, Nicholas B.; Blangero, John; Boomsma, Dorret I.; Brodaty, Henry; Brouwer, Rachel M.; Bülow, Robin; Bøen, Rune; Cahn, Wiepke; Calhoun, Vince D.; Caspers, Svenja; Ching, Christopher R. K.; Cichon, Sven; Ciufolini, Simone; Crespo-Facorro, Benedicto; Curran, Joanne E.; Dale, Anders M.; Dalvie, Shareefa; Dazzan, Paola; de Geus, Eco J. C.; Zubicaray, Greig I. de; Zwarte, Sonja M. C. de; Desrivieres, Sylvane; Doherty, Joanne L.; Donohoe, Gary; Draganski, Bogdan; Ehrlich, Stefan; Eising, Else; Espeseth, Thomas; Fejgin, Kim; Fisher, Simon E.; Fladby, Tormod; Frei, Oleksandr; Frouin, Vincent; Fukunaga, Masaki; Gareau, Thomas; Ge, Tian; Glahn, David C.; Grabe, Hans J.; Groenewold, Nynke A.; Gustafsson, Omar; Haavik, Jan; Haberg, Asta Kristine; Hall, Jeremy; Hashimoto, Ryota; Hehir-Kwa, Jayne Y.; Hibar, Derrek P.; Hillegers, Manon H. J.; Hoffmann, Per; Holleran, Laurena; Holmes, Avram J.; Johansson, Stefan; Jönsson, Erik Gunnar; Hellard, Stephanie Francoise Claire Le; Lundervold, Arvid; Lundervold, Astri J.; Moberget, Torgeir; Nordvik, Jan Egil; Sando, Sigrid Botne; Steen, Vidar Martin; Tamnes, Christian Krog; Agartz, Ingrid; Djurovic, Srdjan; Westlye, Lars Tjelta; Andreassen, Ole (Journal article; Peer reviewed, 2021)
      Low-frequency 1q21.1 distal deletion and duplication copy number variant (CNV) carriers are predisposed to multiple neurodevelopmental disorders, including schizophrenia, autism and intellectual disability. Human carriers ...

    • 2-hydroxyglutarate as a magnetic resonance biomarker for glioma subtyping 

      Esmaeili, Morteza; Vettukattil, Riyas M; Bathen, Tone Frost (Journal article; Peer reviewed, 2013)
      Mutations in the isocitrate dehydrogenase (IDH) genes are frequently found in gliomas and in a fraction of acute myeloid leukemia patients. This results in the production of an oncometabolite, 2-hydroxyglutarate (2-HG). ...

    • 2019 EACTS/EACTA/EBCP guidelines on cardiopulmonary bypass in adult cardiac surgery. 

      Wahba, Alexander; Milojevic, Milan; Boer, Christa; De Somer, Filip M.J.J.; Gudbjartsson, Tomas; van den Goor, Jenny; Jones, Timothy J.; Lomivorotov, Vladimir; Merkle, Frank; Ranucci, Marco; Kunst, Gudrun; Puis, Luc (Peer reviewed; Journal article, 2019)

    • 30-day mortality in patients after hip fracture surgery: A comparison of the Charlson Comorbidity Index score and ASA score used in two prediction models 

      Haugan, Kristin; Klaksvik, Jomar; Foss, Olav A. (Peer reviewed; Journal article, 2021)
      Objective: To compare the Charlson Comorbidity Index (CCI) and American Society of Anesthesiologists (ASA) Physical Status Classification used in two prediction models for 30-day mortality after hip fracture surgery. Study ...

    • A 32-year longitudinal study of alcohol consumption in Swedish women: Reduced risk of myocardial infarction but increased risk of cancer. 

      Hange, Dominique; Sigurdsson, Johann Agust; Björkelund, Cecilia; Sundh, Valter; Bengtsson, Calle (Peer reviewed; Journal article, 2015)
      Objective. To assess associations between the intake of different types of alcoholic beverages and the 32-year incidence of myocardial infarction, stroke, diabetes, and cancer, as well as mortality, in a middle-aged female ...

    • A 39 kb structural variant causing Lynch Syndrome detected by optical genome mapping and nanopore sequencing 

      Bjørnstad, Pål Marius; Aaløkken, Ragnhild Margrethe; Åsheim, June; Sundaram, Arvind; Nangota Felde, Caroline; Østby, Gina Henriette; Dalland, Marianne; Sjursen, Wenche; Carrizosa, Christian; Vigeland, Magnus Dehli; Sorte, Hanne Sørmo; Sheng, Ying; Ariansen, Sarah Louise; Grindedal, Eli Marie; Gilfillan, Gregor (Peer reviewed; Journal article, 2023)
      Lynch Syndrome (LS) is a hereditary cancer syndrome caused by pathogenic germline variants in one of the four mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2. It is characterized by a significantly increased risk of ...

    • 3CAPS - A structural AP-site analogue as a tool to investigate DNA base excision repair 

      Schürmann, David; Scheidegger, Simon P.; Weber, Alain R.; Bjørås, Magnar; Leumann, Christian J.; Schär, Primo (Peer reviewed; Journal article, 2016)
      Abasic sites (AP-sites) are frequent DNA lesions, arising by spontaneous base hydrolysis or as intermediates of base excision repair (BER). The hemiacetal at the anomeric centre renders them chemically reactive, which ...

    • 3D Myocardial Mechanical Wave Measurements: Toward In Vivo 3D Myocardial Elasticity Mapping 

      Salles, Sebastien; Espeland, Torvald; Rodriguez-Molares, Alfonso; Aase, Svein Arne; Hammer, Tommy; Støylen, Asbjørn; Aakhus, Svend; Løvstakken, Lasse; Torp, Hans (Peer reviewed; Journal article, 2020)
      Objectives This study aimed to investigate the potential of a novel 3-dimensional (3D) mechanical wave velocity mapping technique, based on the natural mechanical waves produced by the heart itself, to approach a noninvasive ...

    • 3D ultrasound reconstruction algorithms from analog and digital data 

      Solberg, Ole Vegard; Lindseth, Frank; Bø, Lars Eirik; Muller, Sebastien; Meland, Janne Beate Lervik; Tangen, Geir Arne; Hernes, Toril A. Nagelhus (Journal article; Peer reviewed, 2010)
      Freehand 3D ultrasound is increasingly being introduced in the clinic for diagnostics and image-assisted interventions. Various algorithms exist for combining 2D images of regular ultrasound probes to 3D volumes, being ...

    • 3α,7-Dihydroxy-14(13→12)abeo-5β,12α(H),13β(H)-cholan-24-oic Acids Display Neuroprotective Properties in Common Forms of Parkinson’s Disease 

      Luxenburger, Andreas; Clemmens, Hannah; Hastings, Christopher; Harris, Lawrence D.; Ure, Elizabeth M.; Cameron, Scott A.; Aasly, Jan; Bandmann, Oliver; Weymouth-Wilson, Alex; Furneaux, Richard H.; Mortiboys, Heather (Peer reviewed; Journal article, 2023)
      Parkinson’s Disease is the most common neurodegenerative movement disorder globally, with prevalence increasing. There is an urgent need for new therapeutics which are disease-modifying rather than symptomatic. Mitochondrial ...

    • 5 Years of Exercise Intervention Did Not Benefit Cognition Compared to the Physical Activity Guidelines in Older Adults, but Higher Cardiorespiratory Fitness Did. A Generation 100 Substudy 

      Sokołowski, Daniel; Hansen, Tor Ivar; Rise, Henning Hoel; Reitlo, Line Skarsem; Wisløff, Ulrik; Stensvold, Dorthe; Håberg, Asta (Peer reviewed; Journal article, 2021)
      Background: Aerobic exercise is proposed to attenuate cognitive decline in aging. We investigated the effect of different aerobic exercise interventions and cardiorespiratory fitness (CRF) upon cognition throughout a 5-year ...

    • 5-hydroxymethylcytosine marks mammalian origins acting as a barrier to replication 

      Prikrylova, Terezia; Robertson, Julia; Ferrucci, Francesca; Konorska, Dorota Joanna; Aanes, Håvard; Manaf, Adeel; Zhang, Beibei; Vågbø, Cathrine Broberg; Kusnierczyk, Anna; Gilljam, Karin Margaretha; Løvkvam-Køster, Caroline; Otterlei, Marit; Dahl, John Arne; Enserink, Jorrit; Klungland, Arne; Robertson, Adam Brian (Journal article; Peer reviewed, 2019)
      In most mammalian cells, DNA replication occurs once, and only once between cell divisions. Replication initiation is a highly regulated process with redundant mechanisms that prevent errant initiation events. In lower ...

    • 53BP1 and BRCA1 control pathway choice for stalled replication restart 

      Xu, Yixi; Ning, Shaokai; Wei, Zheng; Xu, Ran; Xu, Xinlin; Xing, Mengtan; Guo, Rong; Xu, Dongyi (Journal article; Peer reviewed, 2017)
      The cellular pathways that restart stalled replication forks are essential for genome stability and tumor prevention. However, how many of these pathways exist in cells and how these pathways are selectively activated ...

    • 8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis 

      Scheffler, Katja; Rachek, Lyudmila; You, Panpan; Rowe, Alexander D.; Wang, Wei; Kuśnierczyk, Anna; Kittelsen, Lene Svendsen; Bjørås, Magnar; Eide, Lars (Journal article; Peer reviewed, 2018)
      Mitochondrial DNA (mtDNA) resides in close proximity to metabolic reactions, and is maintained by the 8-oxoguanine DNA glycosylase (Ogg1) and other members of the base excision repair pathway. Here, we tested the hypothesis ...

    • A 2-year RSA study of the Vanguard CR total knee system: A randomized controlled trial comparing patient-specific positioning guides with conventional technique 

      Øhrn, Frank-David; Leeuwen, Justin Arlen Maarten Joséphus; Tsukanaka, Masako; Röhrl, Stephan Maximillian (Journal article; Peer reviewed, 2018)
      Backgound and purpose - There is some concern regarding the revision rate of the Vanguard CR TKA in 1 registry, and the literature is ambiguous about the effi cacy of patient-specifi c positioning guides (PSPGs). The objective ...

    • A 36-month follow-up of decline in activities of daily living in individuals receiving domiciliary care 

      Helvik, Anne-Sofie; Høgset, Lisbeth Dyrendal; Bergh, Sverre; Saltyte Benth, Jurate; Kirkevold, Øyvind; Selbæk, Geir (Journal article; Peer reviewed, 2015)
      Background There have been few studies of how personal and instrumental activities of daily living (P-ADL and I-ADL) develop over time in older people receiving domiciliary care. This study aimed at assessing variables ...