Blar i Fakultet for medisin og helsevitenskap (MH) på tidsskrift "Frontiers in Neurology"

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    • A European perspective on auditory processing disorder-current knowledge and future research focus 

      Iliadou, Vasiliki; Ptok, Martin; Grech, Helen; Pedersen, Ellen Raben; Brechmann, Andre; Deggouj, Naima; Kiese-Himmel, Christiane; Sliwinska-Kowalska, Mariola; Nickisch, Andreas; Demanez, Laurent; Veuillet, Evelyne; Thai-Van, Hung; Sirimanna, Tony; Callimachou, Marina; Santarelli, Rosamaria; Kuske, Sandra; Barajas, Jose; Hedjever, Mladen; Konukseven, Ozlem; Veraguth, Dorothy; Mattsson, Tone Stokkereit; Martins, Jorge Humberto; Bamiou, Doris-Eva (Journal article; Peer reviewed, 2017)
      Current notions of “hearing impairment,” as reflected in clinical audiological practice, do not acknowledge the needs of individuals who have normal hearing pure tone sensitivity but who experience auditory processing ...

    • Association between gestational levels of toxic metals and essential elements and cerebral palsy in children 

      Weyde, Kjell Vegard F.; Winterton, Adriano; Suren, Pål; Andersen, Guro Lillemoen; Vik, Torstein; Biele, Guido; Knutsen, Helle K.; Thomsen, Cathrine; Meltzer, Helle M.; Skogheim, Thea S.; Engel, Stephanie M.; Aase, Heidi; Villanger, Gro Dehli (Peer reviewed; Journal article, 2023)
      Introduction: Cerebral palsy (CP) is the most common motor disability in childhood, but its causes are only partly known. Early-life exposure to toxic metals and inadequate or excess amounts of essential elements can ...

    • Clinical and Imaging Markers of Prodromal Parkinson's Disease 

      Hustad, Eldbjørg; Aasly, Jan (Peer reviewed; Journal article, 2020)
      The diagnosis of Parkinson's disease (PD) relies on the clinical effects of dopamine deficiency, including bradykinesia, rigidity and tremor, usually manifesting asymmetrically. Misdiagnosis is common, due to overlap of ...

    • Clinical Course in Chronic Subdural Hematoma Patients Aged 18–49 Compared to Patients 50 Years and Above: A Multicenter Study and Meta-Analysis 

      Bartek, Jiri; Sjåvik, Kristin; Dhawan, Sanjay; Sagberg, Lisa Millgård; Kristiansson, Helena; Ståhl, Fredrik; Förander, Petter; Chen, Clark C.; Jakola, Asgeir Store (Journal article; Peer reviewed, 2019)
      Objective: Chronic Subdural Hematoma (cSDH) is primarily a disease of elderly, and is rare in patients <50 years, and this may in part be related to the increased brain atrophy from 50 years of age. This fact may also ...

    • Cognitive rehabilitation in paediatric acquired brain injury—A 2-year follow-up of a randomised controlled trial 

      Sargénius, Hanna Lovise; Andersson, Stein; Haugen, Ingvild; Hypher, Ruth Elizabeth; Brandt, Anne Elisabeth; Finnanger, Torun Gangaune; Rø, Torstein Baade; Risnes, Kari; Stubberud, Jan Egil (Peer reviewed; Journal article, 2023)
      Background: Goal management training (GMT), a metacognitive rehabilitation method that has been demonstrated to improve executive function (EF) in adults with acquired brain injury (ABI), could potentially be effective for ...

    • Connectomics of morphogenetically engineered neurons as a predictor of functional integration in the ischemic brain 

      Sandvig, Axel; Sandvig, Ioanna (Journal article; Peer reviewed, 2019)
      Recent advances in cell reprogramming technologies enable the in vitro generation of theoretically unlimited numbers of cells, including cells of neural lineage and specific neuronal subtypes from human, including ...

    • Developing Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

      Stenberg, Jonas; Karr, Justin E.; Terry, Douglas P.; Saksvik, Simen Berg; Vik, Anne; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Background: Measuring cognitive functioning is common in traumatic brain injury (TBI) research, but no universally accepted method for combining several neuropsychological test scores into composite, or summary, scores ...

    • Ecological validity of a deep learning algorithm to detect gait events from real-life walking bouts in mobility-limiting diseases 

      Romijnders, Robbin; Salis, Francesca; Hansen, Clint; Küderle, Arne; Paraschiv-Ionescu, Anisoara; Cereatti, Andrea; Alcock, Lisa; Aminian, Kamiar; Becker, Clemens; Bertuletti, Stefano; Bonci, Tecla; Brown, Philip; Buckley, Ellen; Cantu, Alma; Carsin, Anne-Elie; Caruso, Marco; Caulfield, Brian; Chiari, Lorenzo; D'Ascanio, Ilaria; Del Din, Silvia; Eskofier, Björn; Fernstad, Sara Johansson; Fröhlich, Marceli Stanislaw; Garcia Aymerich, Judith; Gazit, Eran; Hausdorff, Jeffrey M.; Hiden, Hugo; Hume, Emily; Keogh, Alison; Kirk, Cameron; Kluge, Felix; Koch, Sarah; Mazzà, Claudia; Megaritis, Dimitrios; Micó-Amigo, Encarna; Müller, Arne; Palmerini, Luca; Rochester, Lynn; Schwickert, Lars; Scott, Kirsty; Sharrack, Basil; Singleton, David; Soltani, Abolfazl; Ullrich, Martin; Vereijken, Beatrix; Vogiatzis, Ioannis; Yarnall, Alison; Schmidt, Gerhard; Maetzler, Walter (Peer reviewed; Journal article, 2023)
      Introduction: The clinical assessment of mobility, and walking specifically, is still mainly based on functional tests that lack ecological validity. Thanks to inertial measurement units (IMUs), gait analysis is shifting ...

    • The Effect of Increased Gait Speed on Asymmetry and Variability in Children With Cerebral Palsy 

      Brændvik, Siri Merete; Goihl, Tobias; Braaten, Ragnhild Sunde; Vereijken, Beatrix (Journal article; Peer reviewed, 2020)
      Gait of children and adolescents with cerebral palsy (CP) is often reported to be more asymmetric and variable than gait of typically developing (TD) peers. As this may lead to less stable and less efficient gait, a relevant ...

    • Examining Test-Retest Reliability and Reliable Change for Cognition Endpoints for the CENTER-TBI Neuropsychological Test Battery 

      Stenberg, Jonas; Karr, Justin E.; Karlsen, Rune Hatlestad; Skandsen, Toril; Silverberg, Noah D.; Iverson, Grant L. (Peer reviewed; Journal article, 2020)
      Objective: Seven candidate cognition composite scores have been developed and evaluated as part of a research program designed to validate a cognition endpoint for traumatic brain injury (TBI) research and clinical trials, ...

    • The Human Brain Representation of Odor Identification in Amnestic Mild Cognitive Impairment and Alzheimer's Dementia of Mild Degree 

      Kjelvik, Grete; Evensmoen, Hallvard Røe; Hummel, Thomas; Engedal, Knut; Selbæk, Geir; Saltvedt, Ingvild; Håberg, Asta (Peer reviewed; Journal article, 2020)
      Background: Odor identification (OI) ability is a suggested early biomarker of Alzheimer’s disease. In this study, we investigated brain activity within the brain’s olfactory network associated with OI in patients with ...

    • The Impact of Vascular Risk Factors on Post-stroke Cognitive Impairment: The Nor-COAST Study 

      Aam, Stina; Gynnild, Mari Nordbø; Munthe-Kaas, Ragnhild; Saltvedt, Ingvild; Lydersen, Stian; Knapskog, Anne Brita; Ihle-Hansen, Hege; Ellekjær, Hanne; Eldholm, Rannveig Sakshaug; Fure, Brynjar (Peer reviewed; Journal article, 2021)
      Introduction: Post-stroke cognitive impairment (PSCI) is common, but evidence on the impact of vascular risk factors is lacking. We explored the association between pre-stroke vascular risk factors and PSCI and studied the ...

    • Incidence of mild traumatic brain injury: A prospective hospital, emergency room and general practitioner-based study 

      Skandsen, Toril; Nilsen, Tom Ivar Lund; Einarsen, Cathrine Elisabeth; Normann, Ingunn; McDonagh, David; Håberg, Asta; Vik, Anne (Peer reviewed; Journal article, 2019)
      Background: There are no recent estimates of incidence rates of mild traumatic brain injury (MTBI) from Norway. Moreover, reported incidence rates rarely comprise cases of MTBI evaluated in the primary care setting. In ...

    • Influence of strategic cortical infarctions on pupillary function 

      Peinkhofer, Costanza; Martens, Pernille; Grand, Johannes; Truelsen, Thomas; Knudsen, Gitte M; Kjaergaard, Jesper; Kondziella, Daniel (Journal article; Peer reviewed, 2018)
      Objective: Cortical activity, including cognitive and emotional processes, may influence pupillary function. The exact pathways and the site of cortical pupillary innervation remain elusive, however. We investigated the ...

    • Injury Causes and Severity in Pediatric Traumatic Brain Injury Patients Admitted to the Ward or Intensive Care Unit: A Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study 

      Riemann, Lennart; Zweckberger, Klaus; Unterberg, Andreas; El Damaty, , Ahmed; Younsi, Alexander; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Journal article; Peer reviewed, 2020)
      Background: Traumatic brain injury (TBI) is the leading cause of death and disability in children. It includes a range of different pathologies that differ considerably from adult TBI. Analyzing and understanding injury ...

    • Longitudinal Brain Changes After Stroke and the Association With Cognitive Decline 

      Aamodt, Eva Birgitte; Lydersen, Stian; Alnæs, Dag; SCHELLHORN, TILL; Saltvedt, Ingvild; Beyer, Mona K.; Håberg, Asta (Peer reviewed; Journal article, 2022)
      Background: Cognitive impairment is common after stroke. So is cortical- and subcortical atrophy, with studies reporting more atrophy in the ipsilesional hemisphere than the contralesional hemisphere. The current study ...

    • Longitudinal Monitoring of Parkinson's Disease in Different Ethnic Cohorts: The DodoNA and LONG-PD Study 

      Markopoulou, Katerina; Aasly, Jan; Ju Chung, Sun; Dardiotis, Efthimios; Wirdefeldt, Karin; Premkumar, Ashvini; Schoneburg, Bernadette; Kartha, Ninith; Wilk, Gary; Wei, Jun Rong; Simon, Kelly Claire; Tideman, Samuel; Epshteyn, Alexander; Hadsell, Bryce; Garduno, Lisette; Pham, Anna; Frigerio, Roberta; Maraganore, Demetrius M. (Peer reviewed; Journal article, 2020)
      Background: Different factors influence severity, progression, and outcomes in Parkinson's disease (PD). Lack of standardized clinical assessment limits comparison of outcomes and availability of well-characterized cohorts ...

    • Mitochondrial Mechanisms of LRRK2 G2019S Penetrance 

      Delcambre, Sylvie; Ghelfi, Jenny; Ouzren, Nazzima; Grandmougin, Lea; Delbrouck, Catherine; Seibler, Philip; Wasner, Kobi; Aasly, Jan; Klein, Christine; Trinh, Joanne; Pereira, Sandro L; Grünewald, Anne (Peer reviewed; Journal article, 2020)
      Several mutations in leucine-rich repeat kinase-2 (LRRK2) have been associated with Parkinson's disease (PD). The most common substitution, G2019S, interferes with LRRK2 kinase activity, which is regulated by autophosphorylation. ...

    • Neurodegenerative interplay of cardiovascular autonomic dysregulation and the retina in early multiple sclerosis 

      Benavent, Sigrid Aune de Rodez; Nygaard, Gro Owren; Nilsen, Kristian Bernhard; Etholm, Lars; Sowa, Piotr; Gustavsen, Marte Wendel; Harbo, Hanne Flinstad; Drolsum, Liv; Laeng, Bruno; Kerty, Emilia; Celius, Elisabeth Gulowsen (Journal article; Peer reviewed, 2019)
      Introduction: Autonomic nervous system (ANS) symptoms are prevalent in multiple sclerosis (MS) as is neurodegeneration. Our aim was to explore the occurrence of ANS symptoms and retinal neurodegeneration in a newly diagnosed ...

    • One-Year Prospective Study of Plasma Biomarkers From CNS in Patients With Mild Traumatic Brain Injury 

      Clarke, Gerard Janez Brett; Clarke, Gerard; Skandsen, Toril; Zetterberg, Henrik; Einarsen, Cathrine Elisabeth; Feyling, Casper Kongstein; Follestad, Turid; Vik, Anne; Blennow, Kaj; Håberg, Asta (Peer reviewed; Journal article, 2021)
      Objective: To investigate the longitudinal evolution of three blood biomarkers: neurofilament light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized patients with mild traumatic brain ...