Blar i Fakultet for medisin og helsevitenskap (MH) på tidsskrift "BMC Medicine"

Viser treff 1-19 av 19

    • Assessing causal links between age at menarche and adolescent mental health: a Mendelian randomisation study 

      Askelund, Adrian Dahl; Wootton, Robyn E.; Torvik, Fartein A.; Lawn, Rebecca B.; Ask, Helga; Corfield, Elizabeth C.; Magnus, Maria C.; Reichborn-Kjennerud, Ted; Magnus, Per M.; Andreassen, Ole A.; Stoltenberg, Camilla; Davey Smith, George; Davies, Neil Martin; Havdahl, Alexandra; Hannigan, Laurie John (Journal article; Peer reviewed, 2024)
      Background: The timing of puberty may have an important impact on adolescent mental health. In particular, earlier age at menarche has been associated with elevated rates of depression in adolescents. Previous research ...

    • Bereavement in childhood and young adulthood and the risk of atrial fibrillation: a population-based cohort study from Denmark and Sweden 

      Hua, Chen; Janszky, Imre; Mikael, Rostila; Dang, Wei; Fen, Yang; Jiong, Li; Krisztina, Laszlo (Peer reviewed; Journal article, 2023)
      Background Adverse childhood life events are associated with increased risks of hypertension, ischemic heart disease, and stroke later in life. Limited evidence also suggests that stress in adulthood may increase the risk ...

    • Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis 

      Bouras, Emmanouil; Karhunen, Ville; Gill, Dipender; Huang, Jian; Haycock, Philip C.; Gunter, Marc J.; Johansson, Mattias; Brennan, Paul; Key, Tim; Lewis, Sarah J.; Martin, Richard M.; Murphy, Neil; Platz, Elizabeth A.; Travis, Ruth; Yarmolinsky, James; Zuber, Verena; Martin, Paul; Katsoulis, Michail; Freisling, Heinz; Nøst, Therese Haugdahl; Schulze, Matthias B.; Dossus, Laure; Hung, Rayjean J.; Amos, Christopher I.; Ahola-Olli, Ari; Palaniswamy, Saranya; Männikkö, Minna; Auvinen, Juha; Herzig, Karl-Heinz; Keinänen-Kiukaanniemi, Sirkka; Lehtimäki, Terho; Salomaa, Veikko; Raitakari, Olli; Salmi, Marko; Jalkanen, Sirpa; Jarvelin, Marjo-Riitta; Dehghan, Abbas; Tsilidis, Konstantinos K. (Peer reviewed; Journal article, 2022)
      Background Epidemiological and experimental evidence has linked chronic inflammation to cancer aetiology. It is unclear whether associations for specific inflammatory biomarkers are causal or due to bias. In order to ...

    • Circulating levels of micronutrients and risk of infections: a Mendelian randomization study 

      Flatby, Helene Marie; Ravi, Anuradha; Damås, Jan Kristian; Solligård, Erik; Rogne, Tormod (Peer reviewed; Journal article, 2023)
      Background Micronutrients play an essential role at every stage of the immune response, and deficiencies can therefore lead to increased susceptibility to infections. Previous observational studies and randomized ...

    • Does disease incite a stronger moral appeal than health? 

      Hofmann, Bjørn Morten (Journal article; Peer reviewed, 2023)
      Is disease demotion more important than health promotion? The question is crucial for the ethos of medicine and for priority setting in healthcare. When things get tough, where should our attention and resources go: to ...

    • Endothelial dysfunction in neuroprogressive disorders—causes and suggested treatments 

      Morris, Gerwyn; Puri, Basant K.; Olive, Lisa; Carvalho, Andre; Berk, Michael; Walder, Ken; Gustad, Lise Tuset; Maes, Michael (Peer reviewed; Journal article, 2020)
      Background Potential routes whereby systemic inflammation, oxidative stress and mitochondrial dysfunction may drive the development of endothelial dysfunction and atherosclerosis, even in an environment of low cholesterol, ...

    • Evaluating complex interventions in End of Life Care: the MORECare Statement on good practice generated by a synthesis of transparent expert consultations and systematic reviews 

      Higginson, Irene J.; Evans, Catherine J.; Grande, Gunn; Preston, Nancy; Morgan, Myfanwy; McCrone, Paul; Lewis, Penney; Fayers, Peter; Harding, Richard; Hotopf, Matthew; Murray, Scott A.; Benalia, Hamid; Gysels, Marjolein; Farquhar, Morag; Todd, Chris (Journal article; Peer reviewed, 2013)
      Background Despite being a core business of medicine, end of life care (EoLC) is neglected. It is hampered by research that is difficult to conduct with no common standards. We aimed to develop evidence-based guidance on ...

    • Even low level of physical activity is associated with reduced mortality among people with metabolic syndrome, a population based study (the HUNT 2 study, Norway) 

      Stensvold, Dorthe; Nauman, Javaid; Nilsen, Tom Ivar Lund; Wisløff, Ulrik; Slørdahl, Stig Arild; Vatten, Lars Johan (Journal article; Peer reviewed, 2011)
      Background Low levels of physical activity may increase the risk of developing metabolic syndrome, a cluster of metabolic factors that are associated with the risk of premature death. It has been suggested that physical ...

    • External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis 

      Snell, Kym I.E.; Allotey, John; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; Von Dadelszen, Peter; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony; Arenas Ramírez, Javier; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, Ahmet A.; Seed, Paul T.; Prefumo, Federico; da Silva Costa, Fabricio; Groen, Henk; Audibert, Francois; Masse, Jacques; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, Chie; Rumbold, Alice R.; Heinonen, Seppo; Askie, Lisa; Smits, Luc; Vinter, Christina; Magnus, Per; Eero, Kajantie; Villa, Pia M.; Jenum, Anne Karen; Andersen, Louise B.; Norman, Jane E.; Ohkuchi, Akihide; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala; Galindo, Alberto; Herraiz, Ignacio; Carbillon, Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Browne, Joyce L.; Moons, Karel G.M.; Riley, Richard D.; Thangaratinam, Shakila (Peer reviewed; Journal article, 2020)
      Background Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk during pregnancy is required to plan management. Although there are many published ...

    • Geriatric assessment with management for older patients with cancer receiving radiotherapy: a cluster-randomised controlled pilot study 

      Jordhøy, Marit Slaaen; Røyset, Inga Marie; Saltvedt, Ingvild Tina; Grønberg, Bjørn Henning; Halsteinli, Vidar; Døhl, Øystein; Vossius, Corinna Elisabeth; Kirkevold, Øyvind; Bergh, Sverre; Rostoft, Siri; Oldervoll, Line Merethe; Bye, Asta; Melby, Line Kari; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Saltyte Benth, Jurate (Journal article; Peer reviewed, 2024)
      Background: Geriatric assessment and management (GAM) improve outcomes in older patients with cancer treated with surgery or chemotherapy. It is unclear whether GAM may provide better function and quality of life (QoL), ...

    • Investigating the causal interplay between sleep traits and risk of acute myocardial infarction: a Mendelian randomization study 

      Arora, Nikhil; Bhatta, Laxmi; Skarpsno, Eivind Schjelderup; Dalen, Håvard; Åsvold, Bjørn Olav; Brumpton, Ben Michael; Richmond, Rebecca C.; Strand, Linn Beate (Peer reviewed; Journal article, 2023)
      Background Few studies have investigated the joint effects of sleep traits on the risk of acute myocardial infarction (AMI). No previous study has used factorial Mendelian randomization (MR) which may reduce confounding, ...

    • Mendelian randomization analysis of factors related to ovulation and reproductive function and endometrial cancer risk 

      D’Urso, Shannon; Arumugam, Pooja; Weider, Therese; Hwang, Liang-Dar; Bond, Tom A.; Kemp, John P.; Warrington, Nicole Maree; Evans, David M.; O’Mara, Tracy A.; Moen, Gunn-Helen Øiseth (Peer reviewed; Journal article, 2022)
      Background Observational epidemiological studies suggest a link between several factors related to ovulation and reproductive function and endometrial cancer (EC) risk; however, it is not clear whether these relationships ...

    • Multimorbidity and co-occurring musculoskeletal pain do not modify the effect of the selfBACK app on low back pain-related disability 

      Øverås, Cecilie K.; Nilsen, Tom Ivar Lund; Nicholl, Barbara I.; Rughani, Guy; Wood, Karen; Søgaard, Karen; Mair, Frances S.; Hartvigsen, Jan (Peer reviewed; Journal article, 2022)
      Abstract Background SELFBACK, an artificial intelligence (AI)-based app delivering evidence-based tailored self-management support to people with low back pain (LBP), has been shown to reduce LBP-related disability when ...

    • Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: A systematic review and dose-response meta-analysis of prospective studies 

      Aune, Dagfinn; Keum, NaNa; Giovannucci, Edward; Fadnes, Lars T.; Boffetta, Paolo; Greenwood, Darren C; Tonstad, Serena; Vatten, Lars Johan; Riboli, Elio; Norat, Teresa (Peer reviewed; Journal article, 2016)
      Background Although nut consumption has been associated with a reduced risk of cardiovascular disease and all-cause mortality, data on less common causes of death has not been systematically assessed. Previous reviews ...

    • Rehabilitation of executive function in chronic paediatric brain injury: a randomized controlled trial 

      Brandt, Anne Elisabeth; Finnanger, Torun Gangaune; Hypher, Ruth Elizabeth; Rø, Torstein Baade; Skovlund, Eva; Andersson, Stein; Risnes, Kari; Stubberud, Jan Egil (Peer reviewed; Journal article, 2021)
      Background Impaired executive functions (EFs, i.e., purposeful, goal-directed behaviour) cause significant disability after paediatric acquired brain injury (pABI) warranting efficient interventions. Goal Management Training ...

    • Scandinavian guidelines for initial management of minor and moderate head trauma in children. 

      Åstrand, Ramona; Rosenlund, Christina; Undén, Johan; Moen, Kent Gøran (Peer reviewed; Journal article, 2016)
      Background The management of minor and moderate head trauma in children differs widely between countries. Presently, there are no existing guidelines for management of these children in Scandinavia. The purpose of this ...

    • The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: Randomized controlled trial (Oslo Orthogeriatric Trial) 

      Watne, Leiv Otto; Torbergsen, Anne Cathrine; Conroy, Simon; Engedal, Knut; Frihagen, Frede; Hjorthaug, Geir Aasmund; Juliebø, Vibeke; Ræder, Johan; Saltvedt, Ingvild; Skovlund, Eva; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2014)
      Background Delirium is a common complication in patients with hip fractures and is associated with an increased risk of subsequent dementia. The aim of this trial was to evaluate the effect of a pre- and postoperative ...

    • Trajectories of cardiac troponin in the decades before cardiovascular death: a longitudinal cohort study 

      Kimenai, Dorien M.; Anand, Atul; de Bakker, Marie; Shipley, Martin; Fujisawa, Takeshi; Lyngbakken, Magnus Nakrem; Hveem, Kristian; Omland, Torbjørn; Valencia-Hernández, Carlos A.; Lindbohm, Joni V.; Kivimaki, Mika; Singh-Manoux, Archana; Strachan, Fiona E.; Shah, Anoop S. V.; Kardys, Isabella; Boersma, Eric; Brunner, Eric J.; Mills, Nicholas L. (Journal article; Peer reviewed, 2023)

    • Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease 

      Handel, Adam E; Sandve, Geir Kjetil; Disanto, Giulio; Berlanga-Taylor, Antonio; Gallone, Anna; Hanwell, Heather EC; Drabløs, Finn; Giovannoni, Gavin; Ebers, Georg C; Ramagopalan, Sreeram V (Journal article; Peer reviewed, 2013)
      Background Vitamin D insufficiency has been implicated in autoimmunity. ChIP-seq experiments using immune cell lines have shown that vitamin D receptor (VDR) binding sites are enriched near regions of the genome associated ...