Browsing Fakultet for medisin og helsevitenskap (MH) by Author "Ma, Ying Jie"
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Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement
Zhang, Jie; Song, Lihong; Pedersen, Dennis V.; Li, Anna; Lambris, John D.; Andersen, Gregers Rom; Mollnes, Tom Eirik; Ma, Ying Jie; Garred, Peter (Peer reviewed; Journal article, 2020)Properdin stabilizes the alternative C3 convertase (C3bBb), whereas its role as pattern-recognition molecule mediating complement activation is disputed for decades. Previously, we have found that soluble collectin-12 ...