Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 9516-9535 av 14984
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Novel cytokines in growth control and bone disease of multiple myeloma
(Dissertations at the Faculty of Medicine, 0805-7680; 182, Doctoral thesis, 2001)Myelomatose (benmargskreft) er en blodsyk dom som rammer ca 200 nordmenn årlig. Sykdommen kan ikke kureres og karakteriseres av symptomer som benmargssvikt og infeksjonstendenns, men kanskje først og fremst av sykelig ... -
Novel Epigenetic Signatures in Alzheimer’s Disease
(Master thesis, 2022)Millions of people are currently suffering from the neurodegenerative illness, Alzheimer’s disease (AD). This disease is currently untreatable and difficult to diagnose. Oxidative stress has been shown to impact AD and the ... -
Novel genetic loci associated with hippocampal volume
(Journal article; Peer reviewed, 2017)The hippocampal formation is a brain structure integrally involved in episodic memory, spatial navigation, cognition and stress responsiveness. Structural abnormalities in hippocampal volume and shape are found in several ... -
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform
(Peer reviewed; Journal article, 2020)Background Interleukin 6 concentration is associated with myocardial injury, heart failure, and mortality after myocardial infarction. In the Norwegian tocilizumab non-ST-segment-elevation myocardial infarction trial, the ... -
Novel insights into the innate immune responses to human metapneumovirus infection or changes in osmolality
(Doctoral theses at NTNU;2018:323, Doctoral thesis, 2018)Ny innsikt i de medfødte immunresponsene mot humant metapneumovirus infeksjon eller endringer i osmolalitet Sammendraget: Kroppens medfødte immunsystem gir umiddelbar beskyttelse mot infeksjoner og styrer de påfølgende ... -
Novel insights on human-virus interactions through genome-wide approaches
(Doctoral theses at NTNU;2019:113, Doctoral thesis, 2019)Virus er en viktig årsak til sykdom og død blant mennesker over hele verden. Symptomer påvirusinfeksjoner spenner fra lett forkjølelse til livstruende sykdomstilstand. Virale patogener som Human Immunodeficiency Virus ... -
A novel method for the translation and cross-cultural adaptation of health-related quality of life patient-reported outcome measurements
(Peer reviewed; Journal article, 2023)Background This paper presents a novel methodology for translation and cross-cultural adaptation of health-related quality-of-life patient-reported outcome measures, incorporating the Delphi method. Specifically, we ... -
Novel Model Selection Criterion for Inference of Ising Models
(Master thesis, 2021)In this thesis we evaluate the performance of the novel Model Selection criteria proposed in Bulso et al. 2019, for inference of network topologies. To this purpose, we consider networks of binary nodes whose probability ... -
A novel MRI index for paraspinal muscle fatty infiltration: reliability and relation to pain and disability in lumbar spinal stenosis: results from a multicentre study
(Peer reviewed; Journal article, 2022)Background Fatty infiltration of the paraspinal muscles may play a role in pain and disability in lumbar spinal stenosis. We assessed the reliability and association with clinical symptoms of a method for assessing fatty ... -
Novel Peptides Targeting the β-Clamp Rapidly Kill Planktonic and Biofilm Staphylococcus epidermidis Both in vitro and in vivo
(Peer reviewed; Journal article, 2021)Antimicrobial resistance is an increasing threat to global health and challenges the way we treat infections. Peptides containing the PCNA interacting motif APIM (APIM-peptides) were recently shown to bind to the bacterial ... -
A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
(Peer reviewed; Journal article, 2022)Ischemic injury worsens upon return of blood and innate immunity including the complement system play a central role in ischemia-reperfusion injury (IRI) as in thoracic aortic surgery. Complement component1 inhibitor ... -
A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings
(Peer reviewed; Journal article, 2023)Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We ... -
Novel Synergistic Anti-Enteroviral Drug Combinations
(Peer reviewed; Journal article, 2022)Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: ... -
Novel UCHL1 mutations reveal new insights into ubiquitin processing
(Journal article; Peer reviewed, 2017)Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 has been implicated in early-onset progressive neurodegeneration (MIM no. 615491), so far only in one family. In this study a second family is characterized, ... -
Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development
(Peer reviewed; Journal article, 2019)Global microarray gene expression analyses previously demonstrated differences in female and male embryos during neurodevelopment. In particular, before sexual maturation of the gonads, the differences seem to concentrate ... -
NR4A2 Is Regulated by Gastrin and Influences Cellular Responses of Gastric Adenocarcinoma Cells
(Journal article; Peer reviewed, 2013) -
NR4A2 Is Regulated by Gastrin and Influences Cellular Responses of Gastric Adenocarcinoma Cells
(Journal article; Peer reviewed, 2013)The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in ... -
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells
(Peer reviewed; Journal article, 2013)The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ... -
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells
(Peer reviewed; Journal article, 2013)The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ... -
NREM Sleep Parasomnias Commencing in Childhood: Trauma and Atopy as Perpetuating Factors
(Peer reviewed; Journal article, 2022)Objective/Background: Phenotyping of non-rapid-eye-movement (NREM) parasomnias is currently poorly undertaken. This study aimed to determine whether there are differences phenotypically among childhood-, adolescent-, and ...