Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 11742-11761 av 14995
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A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres
(Peer reviewed; Journal article, 2021)Telomerase negative cancer cell types use the Alternative Lengthening of Telomeres (ALT) pathway to elongate telomeres ends. Here, we show that silencing human DNA polymerase (Pol λ) in ALT cells represses ALT activity and ... -
A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis
(Peer reviewed; Journal article, 2023)Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung disease characterized by damage to the alveolar epithelium, leading to fibrosis and excessive accumulation of extracellular matrix in the ... -
The role of Alkyladenine DNA glycosylase (AAG) beyond canonical base excision repair
(Doctoral theses at NTNU;2021:256, Doctoral thesis, 2021) -
The role of alkylation stress response in anticancer drug resistance
(Doctoral theses at NTNU;2020:114, Doctoral thesis, 2020) -
The Role of Anger in Motivating Leadership
(Peer reviewed; Journal article, 2021)As doctors, we see every working day the pervasive effects of different forms of structural violence and discrimination that undermine the hopes and aspirations of those on the losing side. This leads to powerlessness, ... -
Role of APIM in the NF-κB signaling network
(Master thesis, 2011)Decades of research have revealed that the nuclear factor-κB (NF-κB) is an important functional transcription factor which lately is also found to be constitutively active in many cancer cells such as multiple myeloma cell ... -
Role of Autoimmune Gastritis in Gastric Cancer
(Journal article; Peer reviewed, 2019)It has been known for 70 years that gastric cancer occurs mainly in a stomach with gastritis. Gastritis was previously so prevalent that it was regarded as an aging phenomenon. Since the description of Helicobacter pylori ... -
Role of autoimmunity and over stimulationfor ß-cell deficiency: Epidemiological and therapeutic perspectives
(Doktoravhandlinger ved NTNU, 1503-8181; 2009:221, Doctoral thesis, 2009)Betydningen av diabetesantistoff og β-cellehvile for insulinproduksjonen. Diabetes omfatter flere sykdomsgrupper. Type 1 diabetes er en autoimmun sykdom, dvs. antistoff bryter ned de insulinproduserende cellene (β-cellene). ... -
The role of cardiovascular risk factors in maternal cardiovascular disease according to offspring birth characteristics in the HUNT study
(Peer reviewed; Journal article, 2021)A history of preterm or small (SGA) or large (LGA) for gestational age offspring is associated with smoking and unfavorable levels of BMI, blood pressure, glucose and lipids. Whether and to what extent the excess cardiovascular ... -
Role of CD5L in control of human innate immune function
(Doctoral theses at NTNU;2018:395, Doctoral thesis, 2018)Innate immune signaling has numerous ways to sense changes in cellular metabolism to ensure appropriate response to threatening agents. For instance, cholesterol metabolites act as ligands for nuclear receptor transcription ... -
Role of enteropathogenic Escherichia coli in childhood diarrhoea in Norway
(Doktoravhandlinger ved NTNU, 1503-8181; 2007:260, Doctoral thesis, 2007)Background Diarrhoeal diseases are among the leading causes of illness and death among children in developing countries, and do also cause considerable morbidity in industrialized countries. Enteropathogenic E. coli (EPEC), ... -
Role of Esx-3 Secretion System and Stress Response in Mycobacteria smegmatis
(Master thesis, 2015)Background: Bacteria secrets proteins to manipulate their growth environments through various secretion systems. Type VII systems are important protein secretary systems known in mycobacteria. 5 different Type VII systems ... -
The role of external power demand on the choice of technique in classic cross-country skiing
(Peer reviewed; Journal article, 2023)In cross-country skiing, athletes use different techniques akin to locomotor gaits such as walking and running. Transitions between these techniques generally depend on speed and incline, in a similar way as walk-run ... -
Role of fungal burden in risk stratification of HIV-negative patients with Pneumocystis pneumonia: A 12-year, retrospective, observational, multicenter cohort
(Peer reviewed; Journal article, 2023)Objectives This study aimed to explore the role of fungal burden in risk stratification of patients without HIV-negative patients with Pneumocystis pneumonia (PCP). Methods This was a retrospective analysis of the ... -
The role of hippocampal spatial representations in contextualization and generalization of fear: Fear memory contextualization
(Peer reviewed; Journal article, 2020)Using contextual information to predict aversive events is a critical ability that protects from generalizing fear responses to safe contexts. Animal models have demonstrated the importance of spatial context representations ... -
The Role of IL-32 in Multiple Myeloma
(Doctoral theses at NTNU;2020:256, Doctoral thesis, 2020) -
The role of incline, speed and work rate on the choice of technique in classical roller skiing
(Peer reviewed; Journal article, 2020)Cross-country skiers use different sub-techniques like ‘gears’ (diagonals stride, double poling with kick, and double poling) depending on terrain (incline) and demand (speed and external work rate). Previous studies have ... -
The role of leadership in promoting safety for nursing home residents and preventing elder abuse and neglect
(Doctoral theses at NTNU;2021:99, Doctoral thesis, 2021)This thesis describes the phenomenon of elder abuse and neglect in the institutional context from the perspective of nursing home leaders. Elder abuse and neglect in nursing homes is a complex multifactorial problem and ... -
The role of leptin levels in adaptation to cold climates
(Peer reviewed; Journal article, 2020)Currently, adipose tissue is considered an endocrine organ that produces hormone-active substances, including leptin, which can play a key role in thermoregulation processes. Therefore, we performed a meta-analysis to ... -
Role of NMDA receptors in adult neurogenesis and normal development of the dentate gyrus
(Journal article; Peer reviewed, 2021)The NMDA receptors are a type of glutamate receptors, which is involved in neuronal function, plasticity and development in the mammalian brain. However, how the NMDA receptors contribute to adult neurogenesis and development ...