Browsing Fakultet for medisin og helsevitenskap (MH) by Journals "Alzheimer's & Dementia"

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    • Genetic associations with psychosis and affective disturbance in Alzheimer's disease 

      Antonsdottir, Inga Margaret; Creese, Byron; Klei, Lambertus; DeMichele-Sweet, Mary Ann A.; Weamer, Elise A.; Garcia-Gonzalez, Pablo; Marquié, Marta; Boada, Mercé; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild Tina; Skjellegrind, Håvard Kjesbu; Engdahl, Bo Lars; Andreassen, Ole; Borroni, Barbara; Mecocci, Patrizia; Wedatilake, Yehani; Mayeux, Richard; Foroud, Tatiana M.; Ruiz, Agustin; Lopez, Oscar L.; Kamboh, M. Ilyas; Ballard, Clive; Devlin, Bernie; Lyketsos, Constantine; Sweet, Robert A. (Peer reviewed; Journal article, 2024)
      Introduction: Individuals with Alzheimer's disease (AD) commonly experience neuropsychiatric symptoms of psychosis (AD+P) and/or affective disturbance (depression, anxiety, and/or irritability, AD+A). This study's goal was ...

    • A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease 

      Edwin, Trine Holt; Henjum, Kristi; Nilsson, Lars N. G.; Watne, Leiv; Persson, Karin Ester Torun; Eldholm, Rannveig Sakshaug; Saltvedt, Ingvild; Halaas, Nathalie Bodd; Selbæk, Geir; Engedal, Knut; Strand, Bjørn Heine; Knapskog, Anne Brita (Peer reviewed; Journal article, 2020)
      Introduction: The progression rate of Alzheimer's disease (AD) varies and might be affected by the triggering receptor expressed on myeloid cells (TREM2) activity. We explored if cerebrospinal fluid (CSF) soluble TREM2 ...

    • Higher concentrations of kynurenic acid in CSF are associated with the slower clinical progression of Alzheimer's disease 

      Knapskog, Anne Brita; Aksnes, Mari; Edwin, Trine Holt; Ueland, Per Magne; Ulvik, Arve; Fang, Fei; Eldholm, Rannveig Sakshaug; Halaas, Nathalie Bodd; Saltvedt, Ingvild Tina; Solvang, Stein-Erik Hafstad; Watne, Leiv (Peer reviewed; Journal article, 2023)
      INTRODUCTION The kynurenine pathway's (KP) malfunction is closely related to Alzheimer's disease (AD), for antagonistic kynurenic acid (KA) and agonistic quinolinic acid act on the N-methyl-D-aspartate receptor, a ...