Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 9243-9262 av 15006
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Naloksonnesespray – biotilgjengelighet og opptaksmønster i en fase 1-studie
(Journal article; Peer reviewed, 2019)Kameratredning med nalokson i nesespray kan forebygge dødsfall ved opioidoverdoser. For å få best mulig opptak av nalokson i nesen må sprayen gis med et lavt volum med høy medikamentkonsentrasjon. Målet med studien var å ... -
Naloxone for opioid overdose - Pharmacological aspects and dosing in clinical practice
(Doctoral theses at NTNU;2020:236, Doctoral thesis, 2020)Dødsfall fra opioidoverdoser er et stort folkehelseproblem og utdeling av nesespray med motgiften nalokson var foreslått som et tiltak for å redde liv. I 2012 fantes det ingen godkjente nesesprayer på markedet. Istedenfor ... -
Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium
(Peer reviewed; Journal article, 2020)Compartmentalization of cellular signaling forms the molecular basis of cellular behavior. The primary cilium constitutes a subcellular compartment that orchestrates signal transduction independent from the cell body. ... -
Nanomaterials - Toxic or Therapeutic?
(Master thesis, 2020)Nanomaterialer (NMer), slik som nedbrytningsprodukter av plast og konstruerte medikament leveringspartikler, både slippes ut i miljøet og administreres til mennesker i økende grad. Dette gjør at man stiller spørsmål ved ... -
Nanoparticle delivery to the brain - By focused ultrasound and self-assembled nanoparticle-stabilized microbubbles
(Journal article, 2015)The blood–brain barrier (BBB) constitutes a significant obstacle for the delivery of drugs into the central nervous system (CNS). Nanoparticles have been able to partly overcome this obstacle and can thus improve drug ... -
Nanoparticle Dynamics in Composite Hydrogels Exposed to Low-Frequency Focused Ultrasound
(Peer reviewed; Journal article, 2023)Pulsed focused ultrasound (FUS) in combination with microbubbles has been shown to improve delivery and penetration of nanoparticles in tumors. To understand the mechanisms behind this treatment, it is important to evaluate ... -
Nanoparticle Mediated P-Glycoprotein Silencing for Improved Drug Delivery across the Blood-Brain Barrier: A siRNA-Chitosan Approach
(Journal article; Peer reviewed, 2013)Background: Neonatal intermittent hyperoxia-hypoxia (IHH) is involved in the pathogenesis of retinopathy of prematurity. Whether similar oxygen fluctuations will create pathological changes in the grey and white matter ... -
Nanoparticle-stabilized microbubbles for multimodal imaging and drug delivery
(Journal article, 2015)Microbubbles (MBs) are routinely used as contrast agents for ultrasound imaging. The use of ultrasound in combination with MBs has also attracted attention as a method to enhance drug delivery. We have developed a technology ... -
Nanoparticles, ultrasound and microbubble mediated drug delivery in cancer models
(Doctoral theses at NTNU;2020:97, Doctoral thesis, 2020)Denne avhandlingen omhandler forbedring av kreftbehandling gjennom økt levering av cellegift til kreftvev ved bruk av nanopartikler eller ultralyd kombinert med mikrobobler. Ved å kapsle cellegift inn i nanopartikler kan ... -
Nanoplastics - A Potential Threat To Human Health?
(Master thesis, 2019)Den økende bruken av nanomaterialer i alt fra forbruksprodukter til medisiner har ført til en økende offentlig interesse for hvilke følger eksponeringen kan ha for mennesker og helse. Det å forstå hvilke inflammatoriske ... -
Nanoplastics affect the inflammatory cytokine release by primary human monocytes and dendritic cells
(Peer reviewed; Journal article, 2022)So far, the human health impacts of nano- and microplastics are poorly understood. Thus, we investigated whether nanoplastics exposure induces inflammatory processes in primary human monocytes and monocyte-derived dendritic ... -
Nanostructured lipid carriers for controlled and triggered drug delivery : synthesis and advanced characterisation
(Master thesis, 2016)The emerging field of nanomedicine allows development of targeted drug delivery systems that improves the efficiency and bioavailability of important therapeutics in the clinic. Translation of engineered nanoparticles for ... -
Narcissism in patients admitted to psychiatric acute wards: its relation to violence, suicidality and other psychopathology
(Journal article; Peer reviewed, 2008)Background: The objective was to examine various aspects of narcissism in patients admitted to acute psychiatric wards and to compare their level of narcissism to that of an age- and gendermatched sample from the general ... -
A Narrative Case Study of How Individuals Construct Meaning Concerning Their Situation Through Their Meetings with Work Counsellors
(Journal article; Peer reviewed, 2023)Unemployed individuals with health problems may need extensive work counselling to return to work. Narrative meaning-making processes provide possibilities for healing and change; however, we do not know enough about how ... -
Narrative exposure therapy for refugees and asylum seekers diagnosed with PTSD – a randomized controlled multicenter treatment study
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:321, Doctoral thesis, 2014) -
Narrative Imagination: Staff's stories of relational change
(Journal article; Peer reviewed, 2017)Milieu therapy is an occupation-based treatment aimed at enhancing recovery in mental health patients that is grounded in the healing function of being and doing habitual and creative occupations together, thus transcending ... -
A narrative study of mental health recovery: Exploring unique, open-ended and collective processes.
(Peer reviewed; Journal article, 2020)Purpose: Guided by narrative theory and by use of a narrative-in-action approach, the aim of this study was to explore how mental health recovery unfolds through individuals’ engagement in everyday activities. Method: ... -
Narratives of natural recovery: Youth experiences of social inclusion through Green care
(Journal article; Peer reviewed, 2014)The aim of this study has been to investigate the effects of Green Care services for youth in vulnerable situations risking social exclusion. Green Care enterprises represent alternative arenas in which people can work ... -
Nasal naloxone - A pilot study of the pharmacokinetics of a concentrated formulation
(Master thesis, 2017)Introduction: Naloxone is the antidote against heroin and other opioids. As a measure to combat overdose deaths, nasal naloxone is wanted for bystander administration by lay people. The objective of this study was to ... -
Nasjonal anbefaling for utredning og behandling av døgnrytmelidelser
(Peer reviewed; Journal article, 2023)Nasjonal kompetansetjeneste for søvnsykdommer (fra 2023: Nasjonalt senter for søvnmedisin) nedsatte høsten 2022 en arbeidsgruppe for å utvikle en nasjonal anbefaling for utredning og behandling av døgnrytmelidelser. Gruppen ...