• The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network 

      Selenius, Jannica S.; Silveira, Patricia P.; Salonen, Minna K; Kautiainen, Hannu; von Bonsdorff, Mikaela; Kajantie, Eero Olavi; Lahti, Jari; Eriksson, Johan G.; Wasenius, N. S. (Peer reviewed; Journal article, 2021)
      To investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This ...
    • Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies 

      Dieckmann, Linda; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius; Lahti, Jari; Kvist, Tuomas; Laivuori, Hannele; Sammallahti, Sara; Villa, Pia M.; Suomalainen-König, Sanna; Rancourt, Rebecca C.; Plagemann, Andreas; Henrich, Wolfgang; Eriksson, Johan G.; Kajantie, Eero Olavi; Entringer, Sonja; Braun, Thorsten; Räikkönen, Katri; Binder, Elisabeth B.; Czamara, Darina (Peer reviewed; Journal article, 2022)
      The placenta is a central organ during early development, influencing trajectories of health and disease. DNA methylation (DNAm) studies of human placenta improve our understanding of how its function relates to disease ...
    • Risk-taking behavior of adolescents and young adults born preterm 

      Alenius, Suvi; Kajantie, Eero Olavi; Sund, Reijo; Nurhonen, Markku; Haaramo, Peija; Näsänen-Gilmore, Pieta; Vääräsmäki, Marja; Lemola, Sakari; Räikkönen, Katri; Schnitzlein, Daniel D.; Wolke, Dieter; Gissler, Mika; Hovi, Petteri (Peer reviewed; Journal article, 2023)
      Objectives To study sexually transmitted Chlamydia trachomatis infections (STCTs), teenage pregnancies, and payment defaults in individuals born preterm as proxies for engaging in risk-taking behavior. Study design Our ...
    • School grades and educational attainments of adolescents and young adults born preterm 

      Alenius, Suvi; Kajantie, Eero Olavi; Sund, Reijo; Nurhonen, Markku; Haaramo, Peija; Näsänen-Gilmore, Pieta; Lemola, Sakari; Räikkönen, Katri; Schnitzlein, Daniel D.; Wolke, Dieter; Gissler, Mika; Hovi, Petteri (Peer reviewed; Journal article, 2023)
      Attendance in special education (SE) is more common among individuals born preterm than among those born at term. Less is known about school grades of those born preterm in mainstream education (ME), and how these grades ...
    • Serum ceramides in early pregnancy as predictors of gestational diabetes 

      Mustaniemi, Sanna; Keikkala, Elina; Kajantie, Eero Olavi; Nurhonen, Markku; Jylhä, Antti; Morin-Papunen, Laure; Öhman, Hanna; Männistö, Tuija; Laivuori, Hannele; Eriksson, Johan G.; Laaksonen, Reijo; Vääräsmäki, Marja; Kaaja, Risto; Gissler, Mika; Pouta, Anneli (Peer reviewed; Journal article, 2023)
      Ceramides contribute to the development of type 2 diabetes but it is uncertain whether they predict gestational diabetes (GDM). In this multicentre case–control study including 1040 women with GDM and 958 non-diabetic ...
    • Social functioning in adults born very preterm: Individual participant meta-analysis 

      Ni, Yanyan; Mendonça, Marina; Baumann, Nicole; Eves, Robert; Kajantie, Eero Olavi; Hovi, Petteri; Tikanmaki, Marjaana; Raikkonen, Katri; Heinonen, Kati; Indredavik, Marit S.; Evensen, Kari-Anne I.; Johnson, Samantha; Marlow, Neil; Wolke, Dieter (Journal article; Peer reviewed, 2021)
      CONTEXT: There is a lack of research on individual perceptions of social experiences and social relationships among very preterm (VP) adults compared with term-born peers. OBJECTIVE: To investigate self-perceived social ...
    • The utilization of primary healthcare services among frail older adults – findings from the Helsinki Birth Cohort Study 

      Ikonen, Jenni N; Eriksson, Johan G; von Bonsdorff, Mikaela B; Kajantie, Eero Olavi; Arponen, Otso; Haapanen, Markus J (Peer reviewed; Journal article, 2022)
      Background The impact of frailty on primary healthcare service use, especially general practice office visits and remote contacts, is currently unknown. Further, little is known about the association of frailty with ...
    • The utilization of specialized healthcare services among frail older adults in the Helsinki Birth Cohort Study 

      Ikonen, Jenni N.; Eriksson, Johan G.; Salonen, Minna K.; Kajantie, Eero Olavi; Arponen, Otso; Haapanen, Markus J. (Peer reviewed; Journal article, 2021)
      Background The association between frailty and specialized healthcare utilization is not well studied. We, therefore, examined the utilization of specialized healthcare services among frail Finnish older adults. Methods A ...
    • Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis 

      Allotey, John; Snell, Kym I.E.; Smuk, Melanie; Hooper, Richard; Chan, Claire; Ahmed, Asif; Chappell, Lucy C.; von Dadelszen, Peter; Dodds, Julie; Green, Marcus; Kenny, Louise; Khalil, Asma; Khan, Khalid S.; Mol, Ben W.; Myers, Jenny; Poston, Lucilla; Thilaganathan, Basky; Staff, Anne Cathrine; Smith, Gordon C.S.; Ganzevoort, Wessel; Laivuori, Hannele; Odibo, Anthony O.; Ramírez, Javier A.; Kingdom, John; Daskalakis, George; Farrar, Diane; Baschat, AA; Seed, PT; Prefumo, F; da Silva Costa, F; Groen, H; Audibert, F; Masse, J; Skråstad, Ragnhild Bergene; Salvesen, Kjell Å; Haavaldsen, Camilla; Nagata, C; Rumbold, Alice R.; Heinonen, Seppo; Askie, LM; Smits, LJ; Vinter, CA; Magnus, Per; Kajantie, Eero Olavi; Villa, PM; Jenum, Anne Karen; Andersen, LB; Norman, JE; Ohkuchi, A; Eskild, Anne; Bhattacharya, Sohinee; McAuliffe, Fionnuala M.; Galindo, Alberto; Herraiz, Ignacio; Carbillon, , Lionel; Klipstein-Grobusch, Kerstin; Yeo, SeonAe; Teede, Helena J.; Browne, Joyce L; Moons, Karel G.M.; Riley, Richard D; Thangaratinam, Shakila (Peer reviewed; Journal article, 2020)
      Background: Pre-eclampsia is a leading cause of maternal and perinatal mortality and morbidity. Early identification of women at risk is needed to plan management. Objectives: To assess the performance of existing pre-eclampsia ...
    • Visual function in adults born preterm with very low birth weight—A two-country birth cohort study 

      Kulmala, Maarit; Jørgensen, Anna Perregaard Munch; Aakvik, Kristina Anna Djupvik; Jussinniemi, Laura; Benum, Silje Dahl; Ingvaldsen, Sigrid Hegna; Austeng, Dordi Kristine; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik; Majander, Anna; Morken, Tora Sund (Journal article; Peer reviewed, 2023)
      Purpose: The purpose of the study was to investigate visual function and vision-related general health in adults that were born preterm with very low birth weight (VLBW: birth weight < 1500 g) in their 30s–40s. Methods: ...