Browsing Fakultet for medisin og helsevitenskap (MH) by Title

Now showing items 5475-5494 of 15834

    • Genetic Susceptibility to Preeclampsia: Studies on the Nord-Trøndelag Health Study (HUNT) Cohort, an Australian/New Zealand Family Cohort and Decidua Basalis Tissue 

      Fenstad, Mona Høysæter (Doktoravhandlinger ved NTNU, 1503-8181; 2011:63, Doctoral thesis, 2011)
      Genetisk disposisjon for utvikling av svangerskapsforgiftning : Studier fra Helseundersøkelsen i Nord-Trøndelag, en familiekohort fra Australia/New Zealand og decidua basalis vev Svangerskapsforgiftning er en alvorlig ...

    • Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study 

      Fjukstad, Katrine Kveli; Athanasiu, Lavinia; Bahrami, Shahram; O`Connell, Kevin; van der Meer, Dennis; Bettella, Francesco; Dieset, Ingrid; Steen, Nils Eiel; Djurovic, Srdjan; Spigset, Olav; Andreassen, Ole Andreas (Peer reviewed; Journal article, 2021)
      Selective serotonin reuptake inhibitors (SSRIs) are prescribed both to patients with schizophrenia and bipolar disorder. Previous studies have shown associations between SSRI treatment and cardiometabolic alterations. The ...

    • Genetic variants related to physical activity or sedentary behaviour: a systematic review 

      Aasdahl, Lene; Nilsen, Tom Ivar Lund; Meisingset, Ingebrigt; Nordstoga, Anne Lovise; Evensen, Kari Anne Indredavik; Paulsen, Julie; Mork, Paul Jarle; Skarpsno, Eivind S. (Peer reviewed; Journal article, 2021)
      Background Research shows that part of the variation in physical activity and sedentary behaviour may be explained by genetic factors. Identifying genetic variants associated with physical activity and sedentary behaviour ...

    • Genetic variation and cognitive dysfunction in opioid-treated patients with cancer 

      Kurita, Geana Paula; Ekholm, Ola; Kaasa, Stein; Klepstad, Pål; Skorpen, Frank; Sjøgren, Per (Peer reviewed; Journal article, 2016)
      Background and purpose The effects of single‐nucleotide polymorphisms (SNPs) on the cognitive function of opioid‐treated patients with cancer until now have not been explored, but they could potentially be related to ...

    • Genetic Variation Of Platelet Glycoprotein VI And The Risk Of Venous Thromboembolism 

      Skille, Hanne; Paulsen, Benedikte; Hveem, Kristian; Gabrielsen, Maiken Elvestad; Brumpton, Ben Michael; Hindberg, Kristian; Gran, Olga Vikhammer; Rosendaal, Frits Richard; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article, 2019)

    • Genetic Variation/Evolution and Differential Host Responses Resulting from In-Patient Adaptation of Mycobacterium avium 

      Kannan, Nisha; Lai, Yi-Pin; Haug, Markus; Lilleness, M.K.; Bakke, Siril Skaret; Marstad, Anne; Hov, Håkon; Naustdal, Thor; Afset, Jan Egil; Ioerger, Thomas R.; Flo, Trude Helen; Steigedal, Magnus (Journal article; Peer reviewed, 2019)
      Members of the Mycobacterium avium complex (MAC) are characterized as nontuberculosis mycobacteria and are pathogenic mainly in immunocompromised individuals. MAC strains show a wide genetic variability, and there is growing ...

    • Genetic vs. Aquired fitness: Metabolic, Vascular and Cardiomyocyte Adaptations 

      Haram, Per Magnus (Doktoravhandlinger ved NTNU, 1503-8181; 2006:118, Doctoral thesis, 2006)

    • Genetically controlled mtDNA deletions prevent ROS damage by arresting oxidative phosphorylation 

      Stenberg, Ulf Simon; Li, Jing; Gjuvsland, Arne Bjørke; Persson, Karl; Demitz-Helin, Erik; Gonzalez-Pena, Carles; Yue, Jia-Xing; Gilchrist, Ciaran; Ärengård, Timmy; Ghiaci, Payam; Larsson-Berglund, Lisa; Zackrisson, Martin; Smits, Silvana; Hallin, Johan; Höög, Johanna L.; Molin, Mikael; Liti, Gianni; Omholt, Stig William; Warringer, Jonas (Journal article; Peer reviewed, 2022)

    • Genetically predicted cortisol levels and risk of venous thromboembolism 

      Allarai, Elias; Lee, Wei-Hsuan; Burgess, Stephen; Larsson, Susanna C.; Lindstrom, Sara; Wang, Lu; Smith, Erin N.; Gordon, William; Van Hylckama Vlieg, Astrid; De Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Brumpton, Ben Michael; Chasman, Daniel I.; Suchon, Pierre; Chen, Ming-Huei; Turman, Constance; Germain, Marine; Wiggins, Kerri L.; Macdonald, James; Brækkan, Sigrid Kufaas; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rabecca D.; Nielsen, Jonas B; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; Frazer, Kelly A.; Mccauley, Bryan M.; Taylor, Kent; Pankow, James S.; Reiner, Alexander P.; Gabrielsen, Maiken Elvestad; Deleuze, Jean-Francois; O'Donnell, Chris J.; Kim, Jihye; Mcknight, Barbara; Kraft, Peter; Hansen, John Bjarne; Rosendaal, Frits Richard; Heit, John A.; Psaty, Bruce M.; Tang, Weihong; Kooperberg, Charles; Hveem, Kristian; Ridker, Paul M.; Morange, Pierre-Emmanuel; Johnson, Andrew D.; Kabrhel, Christopher; Alexandretrégouët, David; Smith, Nicholas L. (Peer reviewed; Journal article, 2022)
      Introduction In observational studies, venous thromboembolism (VTE) has been associated with Cushing’s syndrome and with persistent mental stress, two conditions associated with higher cortisol levels. However, it remains ...

    • Genetically-controlled Vesicle-Associated Membrane Protein 1 expression may contribute to Alzheimer's pathophysiology and susceptibility 

      Sevlever, Daniel; Zou, Fang Geng; Ma, Li; Carrasquillo, Sebastian; Crump, Michael G; Culley, Oliver J; Hunter, Talisha A; Bisceglio, Gina; Younkin, Linda; Allen, Mariet; Carrasquillo, Minerva; Sando, Sigrid Botne; Aasly, Jan; Dickson, Dennis W; Graff-Radford, Neill; Petersen, Ronald C.; Morgan, Kevin; Belbin, Olivia (Journal article; Peer reviewed, 2015)
      Background Alzheimer’s disease is a neurodegenerative disorder in which extracellular deposition of β-amyloid (Aβ) oligomers causes synaptic injury resulting in early memory loss, altered homeostasis, accumulation of ...

    • Genetics and Molecular Pathways in Parkinson's disease and Parkinsonism 

      Gustavsson, Karl Emil (Doctoral theses at NTNU;2018:36, Doctoral thesis, 2018)
      In this thesis I used a wide range of genetic methodologies and biological strategies to unravel the genetic bases of parkinsonian disorders and their clinical relevance. First, in Paper I, we present the discovery of a ...

    • Genmodifisert maislinje MON810. Uttalelse fra Faggruppe for genmodifiserte organismer i Vitenskapskomiteen for mattrygghet 09.11.07 

      Berdal, Knut G; Clarke, Jihong; Klemsdal, Sonja; Klungland, Helge; Lid, Elin Thingnæs; Linnestad, Casper; Mikalsen, Arne; Myhr, Anne Ingeborg; Nerland, Audun Helge; Nes, Ingolf; Nielsen, Kaare Magne; Sorteberg, Hilde-Gunn Opsahl; Stabbetorp, Odd Egil; Thrane, Vibeke (VKM Report;, Research report, 2007)

    • Genome editing in food and feed production – implications for risk assessment 

      Bodin, Johanna Eva; Thorstensen, Tage; Alsheikh, Muath K; Basic, Dean; Edvardsen, Rolf Brudvik; Dalen, Knut Tomas; das Neves, Carlos Gonçalo; Duale, Nur; Eklo, Ole Martin; Ergon, Åshild Gunilla; Jevnaker, Anne-Marthe Ganes; Hindar, Kjetil; Håvarstein, Leiv Sigve; Malmstrøm, Martin; Nielsen, Kaare Magne; Olsen, Siri Lie; Rueness, Eli Knispel; Sanden, Monica; Sipinen, Ville Erling; Vikse, Rose; von Krogh, Kristine; Våge, Dag Inge; Wargelius, Anna; Wendell, Micael; Yazdankhah, Siamak Pour; Alexander, Jan; Bruzell, Ellen Merete; Hemre, Gro Ingunn; Vandvik, Vigdis; Agdestein, Angelika; Elvevoll, Edel O.; Hessen, Dag Olav; Hofshagen, Merete; Husøy, Trine; Knutsen, Helle Katrine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Rafoss, Trond; Skjerdal, Olaug Taran; Steffensen, Inger-Lise Karin; Strand, Tor Arne; Velle, Gaute; Wasteson, Yngvild (Peer reviewed; Journal article, 2021)
      The Norwegian Scientific Committee for Food and Environment (VKM) initiated this work to examine the extent to which organisms developed by genome-editing technologies pose new challenges in terms of risk assessment. This ...

    • Genome editing in food and feed production – implications for risk assessment. Scientific Opinion of the Scientific Steering Committee of the Norwegian Scientific Committee for Food and Environment 

      Bodin, Johanna Eva; Thorstensen, Tage; Alsheikh, Muath K; Basic, Dean; Edvardsen, Rolf Brudvik; Dalen, Knut Tomas; Duale, Nur; Eklo, Ole Martin; Ergon, Åshild Gunilla; Jevnaker, Anne-Marthe Ganes; Hindar, Kjetil; Håvarstein, Leiv Sigve; Malmstrøm, Martin; Nielsen, Kaare Magne; Olsen, Siri Lie; Rueness, Eli Knispel; Sanden, Monica; Sipinen, Ville Erling; von Krogh, Kristine; Våge, Dag Inge; Wargelius, Anna; Wendell, Per Hans Micael; Yazdankhah, Siamak Pour; Alexander, Jan; Bruzell, Ellen Merete; Hemre, Gro Ingunn; Vandvik, Vigdis; Agdestein, Angelika; Elvevoll, Edel O.; Hessen, Dag Olav; Hofshagen, Merete; Husøy, Trine; Knutsen, Helle Katrine; Krogdahl, Åshild; Nilsen, Asbjørn Magne; Rafoss, Trond; Skjerdal, Olaug Taran; Steffensen, Inger-Lise Karin; Strand, Tor Arne; Velle, Gaute; Wasteson, Yngvild (Journal article; Peer reviewed, 2021)
      The Norwegian Scientific Committee for Food and Environment (VKM) initiated this work to examine the extent to which organisms developed by genome-editing technologies pose new challenges in terms of risk assessment. This ...

    • Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study 

      Williams, Camilla J.; Li, Zhixiu; Harvey, Nicholas; Lea, Rodney A.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Papadimitriou, Ioannis; Jacques, Macsue; Croci, Ilaria; Stensvold, Dorthe; Wisløff, Ulrik; Taylor, Jenna L.; Gajanand, Trishan; Cox, Emily R.; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Howden, Erin J.; Keating, Shelley E.; Yan, Xu; Bishop, David J.; Bye, Anja; Haupt, Larisa M.; Griffiths, Lyn R.; Ashton, Kevin J.; Brown, Matthew A.; Torquati, Luciana; Eynon, Nir; Coombes, Jeff S. (Peer reviewed; Journal article, 2021)
      Background Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is ...

    • Genome-scale metabolic modelling when changes in environmental conditions affect biomass composition 

      Schulz, Christian; Kumelj, Tjasa; Karlsen, Emil; Almaas, Eivind (Peer reviewed; Journal article, 2021)
      Genome-scale metabolic modeling is an important tool in the study of metabolism by enhancing the collation of knowledge, interpretation of data, and prediction of metabolic capabilities. A frequent assumption in the use ...

    • Genome-scale metabolic models reveal determinants of phenotypic differences in non-Saccharomyces yeasts 

      Pettersen, Jakob Peder; Castillo, Sandra; Jouhten, Paula; Almaas, Eivind (Peer reviewed; Journal article, 2023)
      Background - Use of alternative non-Saccharomyces yeasts in wine and beer brewing has gained more attention the recent years. This is both due to the desire to obtain a wider variety of flavours in the product and to reduce ...

    • Genome-scale reconstructions to assess metabolic phylogeny and organism clustering 

      Schulz, Christian; Almaas, Eivind (Peer reviewed; Journal article, 2020)
      Approaches for systematizing information of relatedness between organisms is important in biology. Phylogenetic analyses based on sets of highly conserved genes are currently the basis for the Tree of Life. Genome-scale ...

    • Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions 

      Khoury, Samar; Parisien, Marc; Thompson, Scott J.; Vachon-Presseau, Etienne; Roy, Mathieu; Mitchell, Amy; Winsvold, Bendik K S; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Fors, Egil Andreas; Heuch, Ingrid; Nielsen, Jonas Bille; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Kania, Artur; Mogil, Jeffrey S.; Diatchenko, Luda (Peer reviewed; Journal article, 2021)
      Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is ...

    • Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles 

      Hautakangas, Heidi; Winsvold, Bendik K S; Ruotsalainen, Sanni; Bjornsdottir, Gyda; Harder, Aster V. E.; Kogelman, Lisette J. A.; Thomas, Laurent; Noordam, Raymond; Benner, Christian; Gormley, Padhraig; Artto, Ville; Banasik, Karina; Bjornsdottir, Anna; Boomsma, Dorret I.; Brumpton, Ben Michael; Burgdorf, Kristoffer Sølvsten; Buring, Julie E.; Chalmer, Mona Ameri; de Boer, Irene; Dichgans, Martin; Erikstrup, Christian; Färkkilä, Markus; Gabrielsen, Maiken Elvestad; Ghanbari, Mohsen; Hagen, Knut; Häppölä, Paavo; Hottenga, Jouke-Jan; Hrafnsdottir, Maria G.; Hveem, Kristian; Johnsen, Marianne Bakke; Kähönen, Mika; Kristoffersen, Espen Saxhaug; Kurth, Tobias; Lehtimäki, Terho; Lighart, Lannie; Magnusson, Sigurdur H.; Malik, Rainer; Pedersen, Ole Birger; Pelzer, Nadine; Penninx, Brenda W. J. H.; Ran, Caroline; Ridker, Paul M.; Rosendaal, Frits Richard; Sigurdardottir, Gudrun R.; Skogholt, Anne Heidi; Sveinsson, Olafur A.; Thorgeirsson, Thorgeir E.; Ullum, Henrik; Zwart, John Anker Henrik (Peer reviewed; Journal article, 2022)
      Migraine affects over a billion individuals worldwide but its genetic underpinning remains largely unknown. Here, we performed a genome-wide association study of 102,084 migraine cases and 771,257 controls and identified ...