Blar i Fakultet for medisin og helsevitenskap (MH) på tidsskrift "Cell reports"

Viser treff 21-27 av 27

    • Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity 

      Alves de Souza, Rodrigo W.; Gallo, David; Lee, Ghee Rye; Katsuyama, Eri; Schaufler, Alexa; Weber, Janick; Csizmadia, Eva; Tsokos, George C.; Koch, Lauren G.; Britton, Steven L.; Wisløff, Ulrik; Brum, Patricia C.; Otterbein, Leo E. (Peer reviewed; Journal article, 2021)
      Physical exercise has profound effects on quality of life and susceptibility to chronic disease; however, the regulation of skeletal muscle function at the molecular level after exercise remains unclear. We tested the ...

    • SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing 

      Kroustallaki, Pinelopi; Lirussi, Lisa; Carracedo, Sergio; You, Panpan; Esbensen, Qin Ying; Götz, Alexandra; Jobert, Laure; Alsøe, Lene; Sætrom, Pål; Gagos, Sarantis; Nilsen, Hilde (Journal article; Peer reviewed, 2019)
      Telomerase biogenesis is a complex process where several steps remain poorly understood. Single-strand-selective uracil-DNA glycosylase (SMUG1) associates with the DKC1-containing H/ACA ribonucleoprotein complex, which is ...

    • Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice 

      Bjørge, Monica Dahl; Hildrestrand, Gunn Annette; Scheffler, Katja; Suganthan, Rajikala; Rolseth, Veslemøy; Kusnierczyk, Anna; Rowe, Alexander D.; Vågbø, Cathrine Broberg; Vetlesen, Susanne; Eide, Lars; Slupphaug, Geir; Yusaku, Nakabeppu; Timothy, Bredy; Klungland, Arne; Bjørås, Magnar (Journal article; Peer reviewed, 2015)
      Ogg1 and Mutyh DNA glycosylases cooperate to prevent mutations caused by 8-oxoG, a major premutagenic DNA lesion associated with cognitive decline. We have examined behavior and cognitive function in mice deficient of these ...

    • Task-dependent mixed selectivity in the subiculum 

      Ledergerber Wäfler, Debora; Battistin, Claudia; Blackstad, Jan Sigurd; Gardner, Richard; Witter, Menno; Moser, May-Britt; Roudi, Yasser; Moser, Edvard Ingjald (Peer reviewed; Journal article, 2021)
      CA1 and subiculum (SUB) connect the hippocampus to numerous output regions. Cells in both areas have place-specific firing fields, although they are more dispersed in SUB. Weak responses to head direction and running speed ...

    • Theta phase-coordinated memory reactivation reoccurs in a slow-oscillatory rhythm during NREM sleep 

      Schreiner, Thomas; Doeller, Christian Fritz Andreas; Jensen, Ole; Rasch, Björn; Staudigl, Tobias (Journal article; Peer reviewed, 2018)
      It has been proposed that sleep’s contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated ...

    • Type I Interferon Induction by Neisseria gonorrhoeae: Dual Requirement of Cyclic GMP-AMP Synthase and Toll-like Receptor 4 

      Andrade, Warrison A; Agarwal, Sarika; Mo, Shunyan; Shaffer, Scott A; Dillard, Joseph P; Schmidt, Tobias; Hornung, Veit; Fitzgerald, Katherine A.; Kurt-Jones, Evelyn A.; Golenbock, Douglas T (Journal article; Peer reviewed, 2016)
      The innate immune system is the first line of defense against Neisseria gonorrhoeae (GC). Exposure of cells to GC lipooligosaccharides induces a strong immune response, leading to type I interferon (IFN) production via ...

    • Zebrafish dorsal habenula is required for updating learned behaviors 

      Palumbo, Fabrizio; Serneels, Bram; Pelgrims, Robbrecht; Yaksi, Emre (Peer reviewed; Journal article, 2020)
      Operant learning requires multiple cognitive processes, such as learning, prediction of potential outcomes, and decision-making. It is less clear how interactions of these processes lead to the behavioral adaptations that ...