Blar i Fakultet for medisin og helsevitenskap (MH) på forfatter "Kajantie, Eero Olavi"
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Early Childhood Growth and Risk of Adult Cerebrovascular Disease: The NFBC1966
Kivelä, Milja; Paananen, Markus; Kajantie, Eero Olavi; Ojaniemi, Marja; Nedelec, Rozenn; Rusanen, Harri; Miettunen, Jouko; Rissanen, Ina (Journal article; Peer reviewed, 2022) -
Early-Life Factors as Predictors of Age-Associated Deficit Accumulation Across 17 Years From Midlife Into Old Age
Haapanen, Markus J.; Jylhävä, Juulia; Kortelainen, Lauri; Mikkola, Tuija M.; Salonen, Minna; Wasenius, Niko S.; Kajantie, Eero Olavi; Eriksson, Johan G.; von Bonsdorff, Mikaela B. (Journal article; Peer reviewed, 2022) -
Effect of High-Dose vs Standard-Dose Vitamin D Supplementation on Neurodevelopment of Healthy Term Infants: A Randomized Clinical Trial
Tuovinen, Soile; Räikkönen, Katri; Holmlund-Suila, Elisa; Hauta-Alus, Helena; Helve, Otto; Rosendahl, Jenni; Enlund-Cerullo, Maria; Kajantie, Eero Olavi; Valkama, Saara; Viljakainen, Heli; Mäkitie, Outi; Andersson, Sture; Heinonen, Kati (Peer reviewed; Journal article, 2021)Importance Vitamin D may be important for neurodevelopment. The optimal daily dose of vitamin D for early brain development is not known. Objectives To test whether a higher (1200 IU) vs standard (400 IU) dose of ... -
Effect of Vitamin D3 Supplementation in the First 2 Years of Life on Psychiatric Symptoms at Ages 6 to 8 Years: A Randomized Clinical Trial
Sandboge, Samuel; Räikkönen, Katri; Lahti-Pulkkinen, Marius; Hauta-Alus, Helena; Holmlund-Suila, Elisa; Girchenko, Polina; Kajantie, Eero Olavi; Mäkitie, Outi; Andersson, Sture; Heinonen, Kati (Peer reviewed; Journal article, 2023)Importance Vitamin D is associated with neurodevelopment, but causality, critical windows, and potentials for modification remain unknown. Objective To determine the impact of high-dose (1200 IU) vs standard-dose (400 ... -
Expiratory airflow in late adolescence and early adulthood in individuals born very preterm or with very low birthweight compared with controls born at term or with normal birthweight: a meta-analysis of individual participant data.
Doyle, Lex W.; Andersson, Sture; Bush, Andy; Cheong, Jeanie L.Y.; Clemm, Hege Synnøve Havstad; Evensen, Kari Anne Indredavik; Gough, Aisling; Halvorsen, Thomas; Hovi, Petteri; Kajantie, Eero Olavi; Lee, Katherine J.; McGarvey, Lorcan; Narang, Indra; Näsänen-Gilmore, Pieta; Steinshamn, Sigurd Loe; Vollsæter, Maria; Vrijlandt, Elianne J.L.E.; APIC, international network (Journal article; Peer reviewed, 2019)Maximal expiratory airflow peaks early in the third decade of life, then gradually declines with age. The pattern of airflow through adulthood for individuals born very preterm (at <32 weeks’ gestation) or ... -
Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia
Wedenoja, Satu; Yoshihara, Masahito; Teder, Hindrek; Sariola, Hannu; Gissler, Mika; Katayama, Shintaro; Wedenoja, Juho; Häkkinen, Inka M.; Ezer, Sini; Linder, Nina; Lundin, Johan; Skoog, Tiina; Sahlin, Ellika; Iwarsson, Erik; Pettersson, Karin; Kajantie, Eero Olavi; Mokkonen, Mikael; Heinonen, Seppo; Laivuori, Hannele; Krjutškov, Kaarel; Kere, Juha (Peer reviewed; Journal article, 2020)Background Fetal immune tolerance is crucial for pregnancy success. We studied the link between preeclampsia, a severe pregnancy disorder with uncertain pathogenesis, and fetal human leukocyte antigen G (HLA-G) and other ... -
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth
Beaumont, Robin N.; Flatley, Christopher; Vaudel, Marc; Wu, Xiaoping; Chen, Jing; Moen, Gunn-Helen Øiseth; Skotte, Line; Helgeland, Øyvind; Solé-Navais, Pol; Banasik, Karina; Albiñana, Clara; Ronkainen, Justiina; Fadista, João; Stinson, Sara Elizabeth; Trajanoska, Katerina; Wang, Carol A.; Westergaard, David; Srinivasan, Sundararajan; Sánchez-Soriano, Carlos; Bilbao, Jose Ramon; Allard, Catherine; Groleau, Marika; Kuulasmaa, Teemu; Leirer, Daniel J.; White, Frédérique; Jacques, Pierre-Étienne; Cheng, Haoxiang; Hao, Ke; Andreassen, Ole; Åsvold, Bjørn Olav; Atalay, Mustafa; Bhatta, Laxmi; Bouchard, Luigi; Brumpton, Ben Michael; Brunak, Søren; Bybjerg-Grauholm, Jonas; Ebbing, Cathrine; Elliott, Paul; Engelbrechtsen, Line; Erikstrup, Christian; Estarlich, Marisa; Franks, Stephen; Gaillard, Romy; Geller, Frank; Grove, Jakob; Hougaard, David M.; Kajantie, Eero Olavi; Morgen, Camilla S.; Nøhr, Ellen Aagaard; Nyegaard, Mette; Palmer, Colin N. A.; Pedersen, Ole Birger; Rivadeneira, Fernando; Sebert, Sylvain; Shields, Beverley M.; Stoltenberg, Camilla; Surakka, Ida; Thørner, Lise Wegner; Ullum, Henrik; Vaarasmaki, Marja; Vilhjalmsson, Bjarni J.; Willer, Cristen J.; Lakka, Timo A.; Gybel-Brask, Dorte; Bustamante, Mariona; Hansen, Torben; Pearson, Ewan R.; Reynolds, Rebecca M.; Ostrowski, Sisse R.; Pennell, Craig E.; Jaddoe, Vincent W. V.; Felix, Janine F.; Hattersley, Andrew T.; Melbye, Mads; Lawlor, Deborah A.; Hveem, Kristian; Werge, Thomas; Nielsen, Henriette Svarre; Magnus, Per Minor; Evans, David M.; Jacobsson, Bo; Järvelin, Marjo-Riitta; Zhang, Ge; Hivert, Marie-France; Johansson, Stefan; Freathy, Rachel M.; Feenstra, Bjarke; Njølstad, Pål Rasmus (Peer reviewed; Journal article, 2023)A well-functioning placenta is essential for fetal and maternal health throughout pregnancy. Using placental weight as a proxy for placental growth, we report genome-wide association analyses in the fetal (n = 65,405), ... -
Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing
Czamara, Darina; Cruceanu, Cristiana; Lahti-Pulkkinen, Marius; Dieckmann, Linda; Ködel, Maik; Sauer, Susann; Rex-Haffner, Monika; Sammallahti, Sara; Kajantie, Eero Olavi; Laivuori, Hannele; Lahti, Jari; Räikkönen, Katri; Binder, Elisabeth B. (Peer reviewed; Journal article, 2022)Several studies have shown that children from pregnancies with estimated first-trimester risk based on fetal nuchal translucency thickness and abnormal maternal serum pregnancy protein and hormone levels maintain a higher ... -
Gestational Age, Parent Education, and Education in Adulthood
Bilsteen, Josephine; Alenius, Suvi; Bråthen, Magne; Børch, Klaus; Ekstrøm, Claus Thorn; Kajantie, Eero Olavi; Lashkarian, Mariam; Nurhonen, Markku; Risnes, Kari Ravndal; Sandin, Sven; Wel, Kjetil A. van der; Wolke, Dieter; Nybo Andersen, Anne-Marie (Journal article; Peer reviewed, 2021)BACKGROUND: Adults born preterm (<37 weeks) have lower educational attainment than those born term. Whether this relationship is modified by family factors such as socioeconomic background is, however, less well known. We ... -
Gestational diabetes is associated with the risk of offspring's congenital anomalies: a register-based cohort study
Kinnunen, Jenni; Nikkinen, Hilkka; Keikkala, Elina; Mustaniemi, Sanna; Gissler, Mika; Laivuori, Hannele; Eriksson, Johan G.; Kaaja, Risto; Pouta, Anneli; Kajantie, Eero Olavi; Vääräsmäki, Marja (Peer reviewed; Journal article, 2023)Background Gestational diabetes mellitus (GDM) is a common pregnancy-related disorder and a well-known risk factor for adverse pregnancy outcomes. There are conflicting findings on the association of GDM with the risk of ... -
Health-related quality of life from 20 to 32 years of age in very low birth weight individuals: a longitudinal study
Berdal, Elias Kjølseth; Wollum, Arnt Erik Karlsen; Hollund, Ingrid Marie Husby; Iversen, Johanne Marie; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2022)Background Preterm birth with very low birth weight (VLBW, birth weight < 1500 g) is associated with health problems later in life. How VLBW individuals perceive their physical and mental health-related quality of life ... -
Health-related quality of life in young adults born small for gestational age: a prospective cohort study
Mehl, Cathrin Vano; Hollund, Ingrid Marie Husby; Iversen, Johanne Marie; Lydersen, Stian; Mork, Paul Jarle; Kajantie, Eero Olavi; Evensen, Kari Anne Indredavik (Peer reviewed; Journal article, 2022)Background Individuals born small for gestational age (SGA) have an increased risk of several adverse health outcomes, but their health-related quality of life (HRQoL) across young adulthood has yet to be studied. The ... -
Healthy ageing from birth to age 84 years in the Helsinki Birth Cohort Study, Finland: a longitudinal study
Mikkola, Tuija M; Kautiainen, Hannu; von Bonsdorff, Mikaela B; Wasenius, Niko S; Salonen, Minna K; Haapanen, Markus J; Kajantie, Eero Olavi; Eriksson, Johan G (Peer reviewed; Journal article, 2023)Background The true prevalence of healthy ageing on a population level is unknown. In this study we aimed to examine the upper limit for the prevalence of healthy ageing, by quantifying the probability of surviving and ... -
Higher carotid-radial pulse wave velocity is associated with non-melancholic depressive symptoms in men–findings from Helsinki Birth Cohort Study
Eriksson, Mia D.; Eriksson, Johan G.; Kautiainen, Hannu; Salonen, Minna K.; Mikkola, Tuija M.; Kajantie, Eero Olavi; Wasenius, N. S.; von Bonsdorff, Mikaela; Korhonen, Päivi; Laine, Merja K. (Peer reviewed; Journal article, 2021)Background: Depression and cardiovascular disease (CVD) are major causes of global disease burden that are interrelated through mostly unknown mechanisms. We studied the relationship of melancholic and non-melancholic ... -
Higher hemoglobin levels are an independent risk factor for gestational diabetes
Sissala, Niina; Mustaniemi, Sanna; Kajantie, Eero Olavi; Vääräsmäki, Marja; Koivunen, Peppi (Peer reviewed; Journal article, 2022)Incidence of gestational diabetes (GDM) has increased rapidly. It poses significant risks for both mother and fetus affecting also negatively their longer-term metabolic heath. We asked whether early pregnancy maternal ... -
Identifying small for gestational age preterm infants from the Finnish Medical Birth Register using eight growth charts
Hocquette, Alice; Pulakka, Anna; Metsälä, Johanna; Heikkilä, Katriina; Zeitlin, Jennifer; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2022) -
Increased interaction and procedural flexibility favoured participation: Study across European cohorts of preterm born individuals
Marques, Sandra CS.; Doetsch, Julia Nadine; Teixeira, Raquel; Abate, Georgia; Brødsgaard, Anne; Brubakk, Ann-Mari; Colombo, Grazia; Cuttini, Marina; Evensen, Kari Anne Indredavik; Hennissen, Vicky; Indredavik, Marit Sæbø; Kajantie, Eero Olavi; Lebeer, Jo; van der Pal, Sylvia; Pedersen, Pernille; Sarrechia, Iemke; Virtanen, Eeva; Barros, Henrique (Peer reviewed; Journal article, 2022)Objective To understand participation and attrition phenomena variability in European cohorts of individuals born preterm through in-depth exploration of the interplay of situational elements involved. Methods Mul ... -
Increased Oral Care Needs and Third Molar Symptoms in Women with Gestational Diabetes Mellitus: A Finnish Gestational Diabetes Case-Control Study
Pukkila, Jenni; Mustaniemi, Sanna; Lingaiah, Shilpa; Lappalainen, Olli-Pekka; Kajantie, Eero Olavi; Pouta, Anneli; Kaaja, Risto; Eriksson, Johan G.; Laivuori, Hannele; Gissler, Mika; Vääräsmäki, Marja; Keikkala, Elina (Peer reviewed; Journal article, 2022)(1) Hyperglycemia and oral pathology accelerate each other in diabetes. We evaluated whether gestational diabetes mellitus (GDM) is associated with self-reported increased oral health care needs and oral symptoms, including ... -
Independent and concomitant associations of gestational diabetes and maternal obesity to perinatal outcome: A register-based study
Ijas, Hilkka; Koivunen, Sanna; Raudaskoski, Tytti; Kajantie, Eero Olavi; Gissler, Mika; Vaarasmaki, Marja (Peer reviewed; Journal article, 2019)Aims Gestational diabetes (GDM) is often accompanied by maternal overweight. Our aim was to evaluate the separate and concomitant effects of GDM and maternal overweight/obesity on perinatal outcomes. Methods We used ... -
Long-term motor outcomes of very preterm and/or very low birth weight individuals without cerebral palsy: A review of the current evidence
Evensen, Kari Anne Indredavik; Ustad, Tordis; Tikanmäki, Marjaana; Haaramo, Peija; Kajantie, Eero Olavi (Peer reviewed; Journal article, 2020)We reviewed literature on long-term motor outcomes of individuals aged five years or older born very preterm (VP: ≤32 weeks of gestation) or with very low birth weight (VLBW: ≤1500g), without cerebral palsy (CP). PubMed ...