Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 13053-13072 av 15027
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Symptoms of depression and risk of abdominal aortic aneurysm: A HUNT study
(Journal article; Peer reviewed, 2019)Background Depression is associated with cardiovascular diseases, but the evidence is scarce regarding depression and risk of abdominal aortic aneurysms (AAA). The aim was to determine whether individuals with depressive ... -
Symptoms of epilepsy and organic brain dysfunctions in patients with acute, brief depression combined with other fluctuating psychiatric symptoms: a controlled study from an acute psychiatric department
(Journal article; Peer reviewed, 2009)Background: In psychiatric acute departments some patients present with brief depressive periods accompanied with fluctuating arrays of other psychiatric symptoms like psychosis, panic or mania. For the purpose of the ... -
Symptoms – prevalence and electronic assessment
(Doctoral theses at NTNU;2020:352, Doctoral thesis, 2020)Symptomer er definert som en subjektiv opplevelse av sykdomstegn som bare kan oppleves og iakttas av den syke selv. En rekke forskjellige symptomer er vanlige i en generell befolkning, utgjør en hyppig årsak for kontakt ... -
Synaptic connectivity of principal cells in layer II of the lateral entorhinal cortex
(Doctoral theses at NTNU;2019:279, Doctoral thesis, 2019) -
Synaptic input as a directional cue for migrating interneuron precursors
(Journal article; Peer reviewed, 2017)During CNS development, interneuron precursors have to migrate extensively before they integrate in specific microcircuits. Known regulators of neuronal motility include classical neurotransmitters, yet the mechanisms that ... -
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice
(Journal article; Peer reviewed, 2015)Ogg1 and Mutyh DNA glycosylases cooperate to prevent mutations caused by 8-oxoG, a major premutagenic DNA lesion associated with cognitive decline. We have examined behavior and cognitive function in mice deficient of these ... -
Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections
(Journal article; Peer reviewed, 2021)Background: There is an urgent need for new antivirals with powerful therapeutic potential and tolerable side effects. Methods: Here, we tested the antiviral properties of interferons (IFNs), alone and with other drugs in ... -
Synergistic Role between p53 and JWA: Prognostic and Predictive Biomarkers in Gastric Cancer
(Journal article; Peer reviewed, 2012)Expression of p53 appears to be correlated to prognosis in patients with malignancy, but its role in gastric carcinoma has remained controversial. Recently we reported that JWA, an ADP-ribosylation-like factor 6 interacting ... -
Syntese av fenylpropanoider ved bruk av trekomponentsyntese med Bestmann-ylid
(Master thesis, 2022)Fenylpropanoider er plante sekundærmetabolitter og har i de siste årene fått oppmerksomhet da de har vist forskjellige biologiske effekter. Målet for dette master prosjektet var å danne et kjemisk bibliotek av fenylpropanoid ... -
Syntetiske studier av chrysogeamide A og B
(Master thesis, 2020)En av de største utfordringene i dagens samfunn er utviklingen av antibiotikaresistens hos bakterier. For å forhindre at bakterielle infeksjoner blir like dødelig som før oppdagelsen av antibiotika er det helt avgjørende ... -
Synthesis and in vitro cellular interactions of superparamagnetic iron nanoparticles with a crystalline gold shell
(Journal article; Peer reviewed, 2014)Fe@Au core–shell nanoparticles (NPs) exhibit multiple functionalities enabling their effective use in applications such as medical imaging and drug delivery. In this work, a novel synthetic method was developed and optimized ... -
Synthesis of Scopularide A and B
(Master thesis, 2020)Scopularid A og B er en del av en familie av sykloheksadepsipeptider som har vist å ha betydelig effekt mot tumorvekst hos visse typer kreftceller. For å studere denne effekten i større detalj, så har det blitt utprøvd en ... -
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
(Peer reviewed; Journal article, 2019)The global spread of antimicrobial resistance and the increasing number of immune‐compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host ... -
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
(Peer reviewed; Journal article, 2019)The global spread of antimicrobial resistance and the increasing number of immune‐compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host ... -
Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53
(Journal article; Peer reviewed, 2019)Non-homologous end joining (NHEJ) is a DNA repair pathway that senses, processes and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. During NHEJ, core Ku70 and Ku80 subunits bind DSBs as a heterodimer ... -
Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70
(Journal article; Peer reviewed, 2017)DNA double-strand breaks (DSBs) are recognized and repaired by the Classical Non-Homologous End-Joining (C-NHEJ) and Homologous Recombination pathways. C-NHEJ includes the core Ku70 and Ku80 (or Ku86) heterodimer that binds ... -
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
(Peer reviewed; Journal article, 2022)Bacterial and mitochondrial DNA, sharing an evolutionary origin, act as danger-associated molecular patterns in infectious and sterile inflammation. They both contain immunomodulatory CpG motifs. Interactions between CpG ... -
Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents
(Peer reviewed; Journal article, 2021)Imidazopyridinones and 7-azaoxindoles are two classes of heterocyclic compounds with only limited previous use in organic and medicinal chemistry. Various synthetic methods and routes have been evaluated to identify safe ... -
Systematic assessment of prescribed medications and short-term risk of myocardial infarction - a pharmacopeia-wide association study from Norway and Sweden
(Journal article; Peer reviewed, 2019)Wholesale, unbiased assessment of Scandinavian electronic health-care databases offer a unique opportunity to reveal potentially important undiscovered drug side effects. We examined the short-term risk of acute myocardial ... -
A systematic review and psychometric evaluation of resilience measurement scales for people living with dementia and their carers
(Peer reviewed; Journal article, 2022)Psychometrically sound resilience outcome measures are essential to establish how health and care services or interventions can enhance the resilience of people living with dementia (PLWD) and their carers. This paper ...