Blar i Fakultet for medisin og helsevitenskap (MH) på tittel
Viser treff 11119-11138 av 15162
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Proteins associated with core biomarkers in early Alzheimer`s disease: A pilot study of levels in cerebrospinal fluid, serum or plasma
(Master thesis, 2014)Background:The cerebrospinal fluid (CSF) biomarkers amyloid-beta 42 (Aβ42), total tau (T-tau) and phosphorylated tau (P-tau) are considered to reflect core pathological features of Alzheimer’s disease (AD), and have ... -
Proteogenomic Analysis to Identify Missing Proteins from Haploid Cell Lines
(Journal article, 2018)Chromosome-centric Human Proteome Project aims at identifying and characterizing protein products encoded from all human protein-coding genes. As of early 2017, 19,837 protein-coding genes have been annotated in the neXtProt ... -
Proteome alterations associated with transformation of multiple myeloma to secondary plasma cell leukemia
(Peer reviewed; Journal article, 2017)Plasma cell leukemia is a rare and aggressive plasma cell neoplasm that may either originate de novo (primary PCL) or by leukemic transformation of multiple myeloma (MM) to secondary PCL (sPCL). The prognosis of sPCL is ... -
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases
(Peer reviewed; Journal article, 2022)Proteome-wide Mendelian randomization (MR) shows value in prioritizing drug targets in Europeans but with limited evidence in other ancestries. Here, we present a multi-ancestry proteome-wide MR analysis based on ... -
Proteomic analysis reveals mechanisms underlying increased efficacy of bleomycin by photochemical internalization in bladder cancer cells
(Peer reviewed; Journal article, 2023)Photochemical internalization (PCI) is a promising new technology for site-specific drug delivery, developed from photodynamic therapy (PDT). In PCI, light-induced activation of a photosensitizer trapped inside endosomes ... -
Proteomic approaches to improve cancer therapy – Identifying factors contributing to melphalan resistance in multiple myeloma and to PDT mediated cytotoxicity
(Doktoravhandlinger ved NTNU, 1503-8181; 2014:147, Doctoral thesis, 2014) -
The Proteomic Landscape of Resting and Activated CD4+ T Cells Reveal Insights into Cell Differentiation and Function
(Peer reviewed; Journal article, 2020)CD4+ T cells (T helper cells) are cytokine-producing adaptive immune cells that activate or regulate the responses of various immune cells. The activation and functional status of CD4+ T cells is important for adequate ... -
Proteomics Analysis of Proteins Involved in DNA Base Repair and Cancer Therapy
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:72, Doctoral thesis, 2012)Proteomikkbasert analyse av proteiner involvert i DNA reparasjon og kreftbehandling DNA reparasjon er grunnleggende for å opprettholdelse levende organismers genom. Forskning i løpet av det siste tiåret har vesentlig økt ... -
Protese vs osteosyntese; gjenvinning av fysisk funksjon hos hoftebruddspasienter over 60 år
(Bachelor thesis, 2021)Ettersom antallet eldre øker vil også forekomsten av hoftebrudd øke. Hvilken operasjonsmetode som er mest hensiktsmessig er debattert og praktiseres ulikt. Denne litteraturstudien ser nærmere på operasjonsmetodene for ... -
Protesepasienters erfaringer med preoperativ informasjon - en systematisk litteraturstudie
(Bachelor thesis, 2017)Hensikt: Hensikten med denne litteraturstudien er å belyse hofte- og kneprotesepasienters erfaring med preoperativ informasjon. Metode: Oppgaven er en systematisk litteraturstudie. Databasene Cinahl Complete og Medline ... -
Prothrombotic genotypes and risk of venous thromboembolism in occult cancer
(Peer reviewed; Journal article, 2021)Background Studies have reported that the combination of some prothrombotic genotypes and overt cancer yields a synergistic effect on VTE risk. Whether individual prothrombotic genotypes or number of risk alleles in a ... -
Protocol for the Cognitive Interventions and Nutritional Supplements (CINS) trial: A randomized controlled multicenter trial of a brief intervention (BI) versus a BI plus cognitive behavioral treatment (CBT) versus nutritional supplements for patients with long-lasting muscle and back pain
(Journal article; Peer reviewed, 2011)Background: Brief intervention programs are clinically beneficial, and cost efficient treatments for low back pain, when offered at 8-12 weeks, compared with treatment as usual. However, about 30% of the patients do not ... -
Protocol for the development of a core outcome set for pelvic girdle pain, including methods for measuring the outcomes: the PGP-COS study
(Journal article; Peer reviewed, 2018)Background Pelvic Girdle Pain (PGP) is an important cause of disability and economic cost worldwide. There is a need for effective preventative and management strategies. Emerging studies measure a variety of outcomes ... -
Protocol for the PreventIT feasibility randomised controlled trial of a lifestyle-integrated exercise intervention in young older adults
(Peer reviewed; Journal article, 2019)Introduction The European population is rapidly ageing. In order to handle substantial future challenges in the healthcare system, we need to shift focus from treatment towards health promotion. The PreventIT project has ... -
Protocol of a randomised, controlled trial comparing immediate curative therapy with conservative treatment in men aged ≥75 years with non-metastatic high-risk prostate cancer (SPCG 19/GRand-P)
(Peer reviewed; Journal article, 2024)Background Older men (aged ≥75 years) with high risk, non-metastatic prostate cancer (PCa) are increasingly treated with curative therapy (surgery or radiotherapy). However, it is unclear if curative therapy prolongs ... -
Proton magnetic resonance metabolomic characterization of ovarian serous carcinoma effusions: chemotherapy-related effects and comparison with malignant mesothelioma and breast carcinoma
(Journal article; Peer reviewed, 2013)Malignant serous effusions are a common manifestation of advanced cancer, associated with significant morbidity and mortality. The aim of this study was to identify the metabolic differences between ovarian serous carcinoma ... -
Proton pump inhibitors and fracture risk. The HUNT study, Norway.
(Journal article; Peer reviewed, 2019)Summary Proton pump inhibitors (PPIs) have been linked to increased risk of fracture; the data have, however, been diverging. We did not find any increased risk of fractures among users of PPIs in a Norwegian population ... -
Proton Pump Inhibitors and Gastric Neoplasia in Man
(Doktoravhandlinger ved NTNU, 1503-8181; 2012:255, Doctoral thesis, 2012) -
Protonterapiens potensiale som behandling av retinoblastom
(Bachelor thesis, 2012)NORSK: I denne oppgaven skal vi se på protonterapiens potensiale som cancerbehandling. Det vi kommer til å se på når det kommer til protonterapi er fysikken bak denne teknikken, nøyaktigheten den kan gi, og eventuelle ...