Browsing Fakultet for medisin og helsevitenskap (MH) by Title
Now showing items 9556-9575 of 15033
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A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
(Peer reviewed; Journal article, 2022)Ischemic injury worsens upon return of blood and innate immunity including the complement system play a central role in ischemia-reperfusion injury (IRI) as in thoracic aortic surgery. Complement component1 inhibitor ... -
A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings
(Peer reviewed; Journal article, 2023)Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We ... -
Novel Synergistic Anti-Enteroviral Drug Combinations
(Peer reviewed; Journal article, 2022)Background: Enterovirus infections affect people around the world, causing a range of illnesses, from mild fevers to severe, potentially fatal conditions. There are no approved treatments for enterovirus infections. Methods: ... -
Novel UCHL1 mutations reveal new insights into ubiquitin processing
(Journal article; Peer reviewed, 2017)Recessive loss of function of the neuronal ubiquitin hydrolase UCHL1 has been implicated in early-onset progressive neurodegeneration (MIM no. 615491), so far only in one family. In this study a second family is characterized, ... -
Novel Y-Chromosome Long Non-Coding RNAs Expressed in Human Male CNS During Early Development
(Peer reviewed; Journal article, 2019)Global microarray gene expression analyses previously demonstrated differences in female and male embryos during neurodevelopment. In particular, before sexual maturation of the gonads, the differences seem to concentrate ... -
NR4A2 Is Regulated by Gastrin and Influences Cellular Responses of Gastric Adenocarcinoma Cells
(Journal article; Peer reviewed, 2013) -
NR4A2 Is Regulated by Gastrin and Influences Cellular Responses of Gastric Adenocarcinoma Cells
(Journal article; Peer reviewed, 2013)The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in ... -
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells
(Peer reviewed; Journal article, 2013)The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ... -
NR4A2 is regulated by Gastrin and involved in gastrin-induced migration and invasion of gastric adenocarcinoma cells
(Peer reviewed; Journal article, 2013)The peptide hormone gastrin is known to play a role in differentiation, growth and apoptosis of cells in the gastric mucosa. In this study we demonstrate that gastrin induces Nuclear Receptor 4A2 (NR4A2) expression in the ... -
NREM Sleep Parasomnias Commencing in Childhood: Trauma and Atopy as Perpetuating Factors
(Peer reviewed; Journal article, 2022)Objective/Background: Phenotyping of non-rapid-eye-movement (NREM) parasomnias is currently poorly undertaken. This study aimed to determine whether there are differences phenotypically among childhood-, adolescent-, and ... -
NRF2 drives an oxidative stress response predictive of breast cancer
(Peer reviewed; Journal article, 2022)Many breast cancer patients are diagnosed with small, well-differentiated, hormone receptor-positive tumors. Risk of relapse is not easily identified in these patients, resulting in overtreatment. To identify metastasis-related ... -
NTNU intranasal naloxone trial (NINA-1) study protocol for a double-blind, double-dummy, non-inferiority randomised controlled trial comparing intranasal 1.4 mg to intramuscular 0.8 mg naloxone for prehospital use
(Peer reviewed; Journal article, 2020)Abstract Introduction Intranasal naloxone is widely used to treat opioid overdoses. The advantage of nasal administration compared to injection lies in its suitability for administration by lay people as it is needless. ... -
Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis
(Peer reviewed; Journal article, 2021)Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of ... -
Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis
(Journal article; Peer reviewed, 2021)Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of ... -
Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA
(Journal article; Peer reviewed, 2012)Proliferating cell nuclear antigen (PCNA) is an essential protein for DNA replication, DNA repair, cell cycle regulation, chromatin remodeling, and epigenetics. Many proteins interact with PCNA through the PCNA interacting ... -
Nudging in screening: Literature review and ethical guidance
(Journal article; Peer reviewed, 2018)Objectives Nudging is the purposeful alteration of choices presented to people that aims to make them choose in predicted ways. While nudging has been used to assure high uptake and good outcome of screening programs, it ... -
Nudos mentales : Salud mental : Una introducción
(Book, 2012-04-23)Boken er primært rettet mot studenter innenfor områdene helse- og sosialfag. Den vil også være nyttig for mennesker med psykiske problemer og deres pårørende, og for helsepersonell for øvrig. Et viktig mål med denne boken ... -
Number of Chronic Nighttime Insomnia Symptoms and Risk of Chronic Widespread Pain and Pain-Related Disability: The HUNT Study
(Peer reviewed; Journal article, 2019)Study Objectives: To examine the association between the number of chronic nighttime insomnia symptoms and the risk of chronic widespread pain (CWP) and pain-related disability. Methods: A prospective study of 10,847 ... -
Nurse-administered intravitreal injections of anti-VEGF: study protocol for noninferiority randomized controlled trial of safety, cost and patient satisfaction
(Journal article; Peer reviewed, 2016)Background: Intravitreal injections (IVI) of anti-vascular endothelial growth factor (anti-VEGF) now improve or stabilize visual acuity in a number of previously untreatable eye diseases, of which the main are age-related ... -
Nurse-patient interaction and self-transcendence: assets for a meaningful life in nursing home residents?
(Peer reviewed; Journal article, 2020)Background Due to the shift to an older population worldwide and an increased need for 24-h care, finding new and alternative approaches to increase wellbeing among nursing home (NH) residents is highly warranted. To guide ...