Blar i Institutt for kjemi på emneord "Chemistry, Organisk kjemi"
Viser treff 1-13 av 13
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Bioassay-guided isolation and identification of anti-inflammatory compounds in Sclerochloa Dura
(Master thesis, 2018)Sclerochloa dura was known to have anti-inflammatory properties and the aim of this thesis is to isolate and identify compounds that are present in fractions and has high inhibition level against arachidonic acid (AA) when ... -
Regioselective Protection and Functionalization of C-6 in The Synthesis Towards Sulfoquinovoses
(Master thesis, 2018)The main goal of this thesis was to explore and compare two protection strategies yielding 2,3,4-tri-O-benzyl-α-D-glucopyranosides. Further work was done to functionalize the primary 6- hydroxyl position to a sulfonic acid ... -
Studies on Gold-Nitrone Chemistry
(Master thesis, 2017)The gold(I)-nitrone catalysed cyclotrimerization of diaryl propargyl acetals was studied. Gold(I)-nitrone and gold(I)/gold(III)-oxadiazole complexes were also synthesised. -
Synthesis of building blocks for (S)-pindolol and vitamin K2 by use of lipase catalysis
(Master thesis, 2018)The objective of this thesis has been to synthesize an enantiopure building block of beta-blocker (S)-pindolol. This has been attempted by organic synthesis followed by lipase catalysis using candida antarctica lipase B ... -
Synthesis of Cationic Amphiphiles Based on L-Tartaric Acid Scaffolds for Antimicrobial Screening
(Master thesis, 2018)Infectious diseases are still one of the main causes of death nowadays. The development of new antibiotics it is still as necessary as it was when penicillin was first discovered in 1929. As bacteria grow resistant to ... -
Synthesis of conjugated unsaturated Amino Acids
(Master thesis, 2016)Of the three main groups of biomolecules - lipids, carbohydrates and proteins - lipids and carbohydrates containing polyene functionalities have already been investigated. This thesis describes a first approach to the ... -
Synthesis of Enantiopure Precursors for Clenbuterol
(Master thesis, 2017)The primary goal of this thesis was to synthesize enantiopure (R)-clenbuterol and its precursors by using enzymes as chiral catalysts. As a secondary goal, the substrate acceptance of ketoreductase 228 (KRED 228) was ... -
Synthesis of enantiopure β-blocker (S)-metoprolol and derivatives by lipase catalysis
(Master thesis, 2016)The goal of this thesis was to synthesize the enantiomerically pure β-blocker (S)-metoprolol through the use of biocatalysis and elucidate potential factors that may influence the selectivity of enzymes. The model substrate ... -
Synthesis of Phenothiazine Derivatives as Potential Non-Fullerene Acceptors for Organic Solar Cells
(Master thesis, 2018)Global emissions need to decline steeply towards 2020, according to the International Energy Agency (IEA). As stated by the IEA, solar photovoltaics accounted for 27% of the overall renewable energy growth in 2017. Organic ... -
Synthesis of Selectively Fully Protected Glucose Derivatives via a Furanose-to-Pyranose Rearrangement Method
(Master thesis, 2018)Towards the total synthesis of a natural anti-inflammatory compound present in the plant Sclerochloa dura, three full protection strategies were developed for selectively full protected glucose derivatives, available for ... -
Synthesis of Small Cationic Amphiphiles for Antimicrobial Screening - Transition Metal Catalyzed Benzene Synthesis and Subsequent Functionalization
(Master thesis, 2016)The goal of this project has been to synthesize small cationic amphiphiles with bulky aromatic substituents on a benzene scaffold, for antimicrobial screening. The aromatic and cationic substituents were chosen based on ... -
Synthesis of Small Cationic Amphiphiles for Antimicrobial Screening - Transition Metal Catalyzed Pyridine Synthesis and Subsequent Functionalization
(Master thesis, 2016)The objective of the present thesis has been the synthesis of small cationic peptidomimetics based on a pharmacophore model devloped by Strøm et al. The peptedomimetics were synthesized by functionalization of substituted ... -
Synthesis of stable isotope labelled cathinone derivatives as internal standards for forensic and pharmaceutical analysis.
(Master thesis, 2016)The synthetic work presented in this thesis has focused on identifying efficient routes towards stable isotope labelled cathinone derivatives. These compounds will act as internal standards for forensic and pharmaceutical ...