Blar i Institutt for kjemi på tidsskrift "Bioorganic & Medicinal Chemistry Letters"

Viser treff 1-2 av 2

    • Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines 

      Reiersølmoen, Ann Christin; Aarhus, Thomas Ihle; Eckelt, Sarah; Nørsett, Kristin Gabestad; Sundby, Eirik; Hoff, Bård Helge (Journal article; Peer reviewed, 2019)
      The epidermal growth factor receptor represents an important target in cancer therapy, and low molecular weight inhibitors based on quinazolines have reached the marked. Herein we report on a new scaffold, 5-aryl-7H-pyrr ...

    • Synthesis and antimicrobial evaluation of cationic low molecular weight amphipathic 1,2,3-triazoles 

      Bakka, Thomas Aleksander; Strøm, Morten B.; Andersen, Jeanette hammer; Gautun, Odd Reidar (Journal article; Peer reviewed, 2017)
      A library of 28 small cationic 1,4-substituted 1,2,3-triazoles was prepared for studies of antimicrobial activity. The structures addressed the pharmacophore model of small antimicrobial peptides and an amphipathic motif ...