Blar i Institutt for kjemi på tidsskrift "Bioorganic & Medicinal Chemistry Letters"
Viser treff 1-2 av 2
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Potent and selective EGFR inhibitors based on 5-aryl-7H-pyrrolopyrimidin-4-amines
(Journal article; Peer reviewed, 2019)The epidermal growth factor receptor represents an important target in cancer therapy, and low molecular weight inhibitors based on quinazolines have reached the marked. Herein we report on a new scaffold, 5-aryl-7H-pyrr ... -
Synthesis and antimicrobial evaluation of cationic low molecular weight amphipathic 1,2,3-triazoles
(Journal article; Peer reviewed, 2017)A library of 28 small cationic 1,4-substituted 1,2,3-triazoles was prepared for studies of antimicrobial activity. The structures addressed the pharmacophore model of small antimicrobial peptides and an amphipathic motif ...