Browsing Institutt for fysikk by Journals "Translational Neurodegeneration"

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    • ApoE Alzheimer’s Disease Aβ-amyloid plaque morphology varies according to APOE isotype 

      Caesar, Ina; Nilsson, K. Peter R.; Hammarström, Per; Lindgren, Olof Mikael; Prokop, Stefan; Heppner, Frank L.; Schmeidler, James; Haroutunian, Vahram; Holtzman, David M.; Hof, Patrick R.; Gandy, Sam (Peer reviewed; Journal article, 2023)
      Background: The apolipoprotein E (APOE, gene; apoE, protein) ε4 allele is the most commonly identified genetic risk factor for typical late-onset sporadic Alzheimer’s disease (AD). Each APOE ε4 allele roughly triples the ...