Blar i Institutt for fysikk på forfatter "Lale, Rahmi"
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Controlling microgel fabrication and advancing understanding of bacterial transcriptional regulation by droplet-based microfluidics
Ahmed, Husnain (Doctoral theses at NTNU;2022:263, Doctoral thesis, 2022)ENGLISH Miniaturization of biological and chemical assays by the invention of Lab-on-a-chip technology has already made significant impacts in scientific domains such as biotechnology, biophysics and biomedicine. Droplet ... -
DNA Condensation by Peptide-Conjugated PAMAM Dendrimers. Influence of Peptide Charge
Dannert, Corinna; Mardal, Ingrid; Lale, Rahmi; Stokke, Bjørn Torger; Dias, Rita (Peer reviewed; Journal article, 2023)Nucleic acid delivery to cells is an important therapeutic strategy that requires the transport of nucleic acids to intracellular compartments and their protection from enzymatic degradation. This can be achieved through ... -
In vitro studies of DNA condensation by bridging protein in a crowding environment
Ramisetty, Sravani Keerthi; Langlete, Petter; Lale, Rahmi; Dias, Rita de Sousa (Journal article; Peer reviewed, 2017)The macromolecules of the bacterial cell occupy 20–40% of the total cytosol volume, and crowded environments have long been known to compact and stabilize DNA. Nevertheless, investigations on DNA-protein binding are generally ... -
Microscale tools for the development of bacterial microarrays
Arnfinnsdottir, Nina Bjørk (Doctoral thesis at NTNU;2016:61, Doctoral thesis, 2016)Heterogeneity within bacterial populations is a phenomenon that has gained much interest over the last decades. It has been shown that even isogeneous colonies under homogeneous conditions can display different phenotypes. ... -
The Design of Simple Bacterial Microarrays: Development towards Immobilizing Single Living Bacteria on Predefined Micro-Sized Spots on Patterned Surfaces
Arnfinnsdottir, Nina Bjørk; Ottesen, Vegar; Lale, Rahmi; Sletmoen, Marit (Journal article; Peer reviewed, 2015)In this paper we demonstrate a procedure for preparing bacterial arrays that is fast, easy, and applicable in a standard molecular biology laboratory. Microcontact printing is used to deposit chemicals promoting bacterial ... -
A Titratable Cell Lysis-on-Demand System for Droplet-Compartmentalised Ultrahigh-Throughput Screening in Functional Metagenomics and Directed Evolution
Wong, Che Fai Alex; Van Vliet, L.; Bhujbal, Swapnil Vilas; Guo, Chengzhi; Sletmoen, Marit; Stokke, Bjørn Torger; Hollfelder, Florian; Lale, Rahmi (Journal article; Peer reviewed, 2021)Water-in-oil emulsion droplets are an attractive format for ultrahigh-throughput screening in functional metagenomics and directed evolution applications that allow libraries with more than 107 members to be characterized ...