Blar i Institutt for bioteknologi og matvitenskap på tidsskrift "Scientific Reports"
Viser treff 1-20 av 28
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An orthogonal system for heterologous expression of actinobacterial lasso peptides in Streptomyces hosts
(Journal article; Peer reviewed, 2018)Lasso peptides are ribosomally synthesized and post-translationally modified peptides produced by bacteria. They are characterized by an unusual lariat-knot structure. Targeted genome scanning revealed a wide diversity of ... -
Anaerobic digestion of pig manure supernatant at high ammonia concentrations characterized by high abundances of Methanosaeta and non-euryarchaeotal archaea
(Journal article; Peer reviewed, 2017)We examined the effect of ammonium and temperature on methane production in high rate upflow anaerobic sludge bed reactors treating pig manure supernatant. We operated four reactors at two ammonium concentrations (‘low’ ... -
Ancient acquisition of "alginate utilization loci" by human gut microbiota
(Journal article; Peer reviewed, 2018)In bacteria from the phylum Bacteroidetes, the genes coding for enzymes involved in polysaccharide degradation are often colocalized and coregulated in so-called “polysaccharide utilization loci” (PULs). PULs dedicated to ... -
Aquaculture rearing systems induce no legacy effects in Atlantic cod larvae or their rearing water bacterial communities
(Peer reviewed; Journal article, 2022)The microbial rearing quality influences the survival of marine larvae. Microbially matured water treatment systems (MMS) provide a more favourable rearing water microbiome than flow-through systems (FTS). It has previously ... -
A comparative study of Atlantic salmon chilled in refrigerated seawater versus on ice: from whole fish to cold-smoked fillets
(Peer reviewed; Journal article, 2020)Water and salt uptake, and water holding capacity (WHC) of whole gutted Atlantic salmon superchilled at sub-zero temperatures in refrigerated seawater (RSW) were compared to traditional ice storage. Following the entire ... -
Correlation between microbiota and growth in Mangrove Killifish (Kryptolebias marmoratus) and Atlantic cod (Gadus morhua)
(Journal article; Peer reviewed, 2016)The vertebrate gut is host to large communities of bacteria, and one of the beneficial contributions of this commensal gut microbiota is the increased nutritional gain from feed components that the host cannot degrade on ... -
Correlations of age and growth rate with microbiota composition in Atlantic cod (Gadus morhua) larvae
(Journal article; Peer reviewed, 2017)Little information is available on the link between host development (growth rate and ontogeny) and the composition of the microbiota in fish larvae. This study was carried out to examine potential correlations of microbiota ... -
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry
(Journal article; Peer reviewed, 2019)The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during early life ... -
Dynamic responses to silicon in Thalassiosira pseudonana - Identification, characterisation and classification of signature genes and their corresponding protein motifs
(Journal article; Peer reviewed, 2017)The diatom cell wall, or frustule, is a highly complex, three-dimensional structure consisting of nanopatterned silica as well as proteins and other organic components. While some key components have been identified, ... -
Effect of design geometry, exposure energy, cytophilic molecules, cell type and load in fabrication of single-cell arrays using micro-contact printing
(Journal article; Peer reviewed, 2020)In this study a range of factors influencing the fabrication of single-cell arrays (SCAs) are identified and investigated. Micro-contact printing was used to introduce spots coated with polyethyleneimine or Matrigel on ... -
Efficient Grafting of Cyclodextrin to Alginate and Performance of the Hydrogel for Release of Model Drug
(Journal article; Peer reviewed, 2019)Controlling the rate of release of molecules from a hydrogel is of high interest for various drug delivery systems and medical devices. A strategy to alter the release profiles of soluble and poorly soluble active ingredients ... -
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
(Peer reviewed; Journal article, 2020)Cell replacement therapies hold great therapeutic potential. Nevertheless, our knowledge of the mechanisms governing the developmental processes is limited, impeding the quality of differentiation protocols. Generating ... -
Functional characterization of a lytic polysaccharide monooxygenase from Schizophyllum commune that degrades non-crystalline substrates
(Journal article; Peer reviewed, 2023)Lytic polysaccharide monooxygenases (LPMOs) are mono-copper enzymes that use O2 or H2O2 to oxidatively cleave glycosidic bonds. LPMOs are prevalent in nature, and the functional variation among these enzymes is a topic of ... -
Functional characterization of three Azotobacter chroococcum alginate-modifying enzymes related to the Azotobacter vinelandii AlgE mannuronan C-5-epimerase family
(Peer reviewed; Journal article, 2020)Bacterial alginate initially consists of 1-4-linked beta-D-mannuronic acid residues (M) which can be later epimerized to alpha-L-guluronic acid (G). The family of AlgE mannuronan C-5-epimerases from Azotobacter vinelandii ... -
Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function
(Journal article; Peer reviewed, 2017)Chitin is an important structural component of numerous fungal pathogens and parasitic nematodes. The human macrophage chitotriosidase (HCHT) is a chitinase that hydrolyses glycosidic bonds between the N-acetyl-D-glucosamine ... -
The impact of phage treatment on bacterial community structure is minor compared to antibiotics
(Peer reviewed; Journal article, 2023)Phage treatment is suggested as an alternative to antibiotics; however, there is limited knowledge of how phage treatment impacts resident bacterial community structure. When phages induce bacterial lysis, resources become ... -
Lipid and DHA-production in Aurantiochytrium sp. – Responses to nitrogen starvation and oxygen limitation revealed by analyses of production kinetics and global transcriptomes
(Journal article; Peer reviewed, 2019)Thraustochytrids of the genera Schizochytrium and Aurantiochytrium accumulate oils rich in the essential, marine n3 fatty acid docosahexaenoic acid (DHA). DHA production in Aurantiochytrium sp T66 was studied with the aim ... -
Mapping anaerobic sludge bed community adaptations to manure supernatant in biogas reactors
(Journal article; Peer reviewed, 2018)In upflow anaerobic sludge bed (UASB) reactors, biomass present as granules allows for long solids retention time. Here, granules from a process treating pulp and paper industrial wastewater were successfully applied as ... -
New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18
(Journal article; Peer reviewed, 2017)Marine actinobacteria are drawing more and more attention as a promising source of new natural products. Here we report isolation, genome sequencing and metabolic profiling of new strain Streptomyces sp. MP131-18 isolated ... -
Nitrifying biofilms deprived of organic carbon show higher functional resilience to increases in carbon supply
(Peer reviewed; Journal article, 2020)In nitrifying biofilms, the organic carbon to ammonia nitrogen (C/N) supply ratio can influence resource competition between heterotrophic and nitrifying bacteria for oxygen and space. We investigated the impact of acute ...