• Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis 

      Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit (Peer reviewed; Journal article, 2021)
      Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of ...
    • Nucleoside Analogues Are Potent Inducers of Pol V-mediated Mutagenesis 

      Sumabe, Balagra Kasim; Ræder, Synnøve Brandt; Røst, Lisa M.; Sharma, Animesh; Donkor, Eric S.; Mosi, Lydia; Duodu, Samuel; Bruheim, Per; Otterlei, Marit (Journal article; Peer reviewed, 2021)
      Drugs targeting DNA and RNA in mammalian cells or viruses can also affect bacteria present in the host and thereby induce the bacterial SOS system. This has the potential to increase mutagenesis and the development of ...
    • Structure–Activity Relationships of Low Molecular Weight Alginate Oligosaccharide Therapy against Pseudomonas aeruginosa 

      Pritchard, Manon F.; Powell, Lydia C.; Adams, Jennifer Y. M.; Menzies, Georgina; Khan, Saira; Tøndervik, Anne; Sletta, Håvard; Aarstad, Olav Andreas; Skjåk-Bræk, Gudmund; McKenna, Stephen; Buurma, Niklaas J.; Farnell, Damian J. J.; Rye, Philip D.; Hill, Katja E.; Thomas, David W. (Peer reviewed; Journal article, 2023)
      Low molecular weight alginate oligosaccharides have been shown to exhibit anti-microbial activity against a range of multi-drug resistant bacteria, including Pseudomonas aeruginosa. Previous studies suggested that the ...