Blar i Institutt for biologi på forfatter "Edvardsen, Rolf Brudvik"
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CRISPR/Cas9-mediated editing of Δ5 and Δ6 desaturases impairs Δ8-desaturation and docosahexaenoic acid synthesis in Atlantic salmon (Salmo salar L.)
Datsomor, Alex Kojo; Olsen, Rolf Erik; Madaro, Angelico; Bones, Atle M.; Edvardsen, Rolf Brudvik; Wargelius, Anna; Winge, Per (Journal article; Peer reviewed, 2019)The in vivo functions of Atlantic salmon fatty acyl desaturases (fads2), Δ6fads2-a, Δ6fads2-b, Δ6fads2-c and Δ5fads2 in long chain polyunsaturated fatty acid (LC-PUFA) synthesis in salmon and fish in general remains to be ... -
Effect of diet on molecular relationships between Atlantic cod larval muscle growth dynamics, metabolism, and antioxidant defense system
Vo, Tu Anh; Galloway, Trina Falck; Arukwe, Augustine; Edvardsen, Rolf Brudvik; Hamre, Kristin; Karlsen, Ørjan; Rønnestad, Ivar; Kjørsvik, Elin (Peer reviewed; Journal article, 2022)We studied molecular effects (RNAseq and qPCR) of first feeding prey types (copepods or rotifers/Artemia) on skeletal muscle myogenesis and growth dynamics (proliferation, differentiation), metabolism (glycolysis, ... -
Impact of Antioxidant Feed and Growth Manipulation on the Redox Regulation of Atlantic Salmon Smolts
Yin, Peng; Bjørnsson, Bjørn Thrandur; Fjelldal, Per Gunnar; Saito, Takaya; Remø, Sofie C.; Edvardsen, Rolf Brudvik; Hansen, Tom Johnny; Sharma, Sandeep; Olsen, Rolf Erik; Hamre, Kristin (Peer reviewed; Journal article, 2022)Accumulating evidence indicates a close relationship between oxidative stress and growth rate in fish. However, the underlying mechanisms of this relationship remain unclear. This study evaluated the combined effect of ... -
Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Jin, Yang; Datsomor, Alex Kojo; Olsen, Rolf Erik; Vik, Jon Olav; Torgersen, Jacob Seilø; Edvardsen, Rolf Brudvik; Wargelius, Anna; Winge, Per; Grammes, Fabian (Peer reviewed; Journal article, 2020)Background With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon ...