Browsing Fakultet for naturvitenskap (NV) by Subject "Industriell kjemi og bioteknologi, Bioteknologi"
Now showing items 1-20 of 45
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Analysis of DNA Repair Proteins and Chromatin Remodeling Factors Using iPOND
(Master thesis, 2012)Most chemotherapeutic treatments rely on induction of severe DNA damage to kill the cancer cells. However, DNA repair pathways can repair the induced lesions, leading to survival of the tumor cells. Thus, inhibition of DNA ... -
Biological and Chemical Stability of Various Preparations of Garlic Extracts
(Master thesis, 2018)The beneficial effects of garlic (Allium Sativum) on cancer and on the cardiovascular system, as well as direct anti-bacterial and anti-viral properties, has been confirmed by multiple research papers, where organosulfur ... -
Characterization of genotype and beer fermentation properties of Norwegian Farmhouse Ale Yeasts
(Master thesis, 2016)Eight different Norwegian Farmhouse Ale Yeasts from Voss, Stranda, Lærdal, Hornindal and Olden were donated to IBT for analysis. The yeast were phenotypically characterized and two beer styles were produced under laboratory ... -
Characterization of Substrate Binding and Hybrid Forming Abilities of Galectin-3
(Master thesis, 2018)Glycans have over the last decade become a hot topic in biochemistry, cell biology and related research areas. Glycoproteins are today known to have critical roles in the organization and function of eukaryotic cells. Their ... -
Composite Hydrogels of Alginate and Cellulose Nanofibrils - A study of mechanical properties
(Master thesis, 2018)The main focus of this thesis was to attain more information about how alginate - CNF composite hydrogels are affected by each of the two polysaccharides, in order to gain additional knowledge which could be used to ... -
Conservation and Evolution of Pairwise Gene Co-Expression Correlations in HIV and TB Co-infected Individuals - A Network-based Analysis of Whole-Blood RNA samples
(Master thesis, 2014)Network analysis of gene co-expression data has been shown to be a strong tool to elucidate biological information from large datasets. In this analysis the goal has been to see if the method developed by Voigt, Nowick & ... -
Construction of XylS/Pm Expression Vectors for Bacillus subtilis - Evaluated in Bacillus subtilis and Lactobacillus plantarum
(Master thesis, 2017)Today, Escherichia coli (E.coli) is widely used as recombinant protein expression host. However, other species could be more suitable to express some recombinant proteins. In the present study, plasmids with XylS/Pm ... -
Degradation of Calcium Gels of Alginate and Periodate Oxidised Alginate
(Master thesis, 2016)The extracellular matrix (ECM) functions as a structural scaffold for cells and controls cellular function through cell-matrix interactions. These interactions are required by most cells in order to maintain viable and ... -
Development of an Analytical Method for the Determination of the Antigen Binding Capacity of Radiolabeled Antibodies
(Master thesis, 2012)The foundation of Algeta's second alpha-pharmaceutical platform is thorium-227, a radionuclide that emits alpha particles with high energy. By linking thorium-227 to tumor binding monoclonal antibodies, Algeta has the ... -
Docosahexanoic Acid (DHA) Production in the Aurantiochytrium Species T66 and S61
(Master thesis, 2016)Enhanced growth of aquaculture is completely dependent of a sufficient supply of the essential omega-3 fatty acid, docosahexanoic acid (DHA), which has beneficial effects on human health. Increasing DHA demand requires new ... -
Effekt av endring i fermenteringsbetingelser på smak, i produksjon av øl
(Master thesis, 2015)Ved produksjon av øl er det hovedsaklig fire ingredienser som brukes: vann, malt, humle og gjær. Gjæren står for fermenteringen av sukker til alkohol, men bidrar også med produksjon av andre smaksstoffer, for eksempel ... -
Endringer i biokjemi og kvalitetsparametre ved lagring og varmebehandling av atlantisk makrell (Scomber scombrus)
(Master thesis, 2017)Atlantisk makrell er en pelagisk fisk som finnes i norske farvann. Makrell er rik på viktige næringsstoffer som lipider og proteiner, og er en god matressurs i et sunt kosthold. Under prosessering og lagring kan verdifulle ... -
Epidemic Network Modeling for the Prediction of the Transmission of Gonorrhea in Norway
(Master thesis, 2018)The number of gonorrhea infections among men who have sex with men (MSM) in Norway continues to rise, and in 2017 the number of infections increased with more than 50 % relative to 2016. This has resulted in various campaigns ... -
Evaluation of Pseudomonas putida and Pseudoalteromonas haloplanktis as Alternative Hosts for Recombinant Gene Expression - by Evaluating the xylS/Pm Expression System with mCherry as Reporter Gene
(Master thesis, 2017)Modern therapeutic proteins, such as insulin, are almost exclusively produced in E. coli. One of the challenges when producing recombinant proteins is solubility: a large fraction of the product is often found in an insoluble ... -
Evaluation of the Pm/XylS expression system for production of IFN-alpha-2b in Cupriavidus necator and Escherichia coli
(Master thesis, 2016)Recombinant bacteria are used for production of human proteins such as the medical important cytokine Interferon-alpha-2b (IFN-α-2b). In the present study, Escheriachia coli (E.coli) and Cupriavidus necator (C.necator) ... -
Evaluation of the XylS/Pm Expression Cassette in Corynebacterium glutamicum
(Master thesis, 2018)For bacteria, the most common expression system for recombinant protein production is Escherichia coli (E. coli). However, a large fraction of recombinant proteins produced in E. coli are in an insoluble form which sometimes ... -
Extraction and characterization of protein from Alaria esculenta, Palmaria palmata and Saccharina latissima
(Master thesis, 2016)Global population growth stimulates the search for new, sustainable ingredients in food and feed. The largest potential for production growth is found in the ocean, including cultivation and harvesting of macroalgae. Today, ... -
Fabrication of Cellular Microarrays
(Master thesis, 2017)Cellular microarrays are known for their use as a tool to investigate variations between single cells in terms of how they respond to different physiological parameters. The work of this thesis focused on developing a ... -
Genotypic and Phenotypic Characterization of Norwegian Farmhouse Ale Yeast Cultures: A Domestication-Driven Evolution
(Master thesis, 2017)There is an immense gap in our knowledge regarding biodiversity of yeasts and the available untapped yeasts that can be found in nature. Studying both domesticated and wild species is important as it can enable us to better ... -
Identification of Antimicrobial Drug Targets from Robustness Properties of Metabolic Networks
(Master thesis, 2015)A reaction universe containing all 13,849 metabolic reactions known to exist was constructed and found to share many topological properties with real-world metabolic networks. Integration of the reaction universe into 43 ...