Browsing Fakultet for naturvitenskap (NV) by Title
Now showing items 10965-10984 of 12512
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Synthesis, identification, chiral separation and crystal structure of (3R,4R,7S,8S)-3,4,7,8-tetrachlorodecane and its stereoisomers
(Peer reviewed; Journal article, 2023)Chlorinated paraffins (CPs) are a notoriously known class of compounds that stand amongst the most wide-spread persistent organic pollutants. Therefore, their reliable, repeatable, and reproducible quantitative analysis ... -
Synthesis, Morphological and Photophysical Characterization of Squaraine Based Chromophores
(Master thesis, 2019)I dette studiet har squaraine-kinolin kromoforer blitt undersøkt mot deres fotofysiske, elektrokjemiske og morfologiske egenskaper. Effekten av forskjellige alkylkjeder på stoffenes adferd ble undersøkt ved bruk av absorpsjon ... -
Synthetic Applications of Nitropyridine Derivatives
(Doktoravhandlinger ved NTNU, 1503-8181; 2010:238, Doctoral thesis, 2010)The present work represents a continuation of the investigation of the chemistry of nitropyridine derivatives, based on the methodology for nitration of pyridines developed by Professor Jan M. Bakke and co-workers at NTNU. ... -
Synthetic biology for drug discovery: construction of biosensors for detection of endogenously produced bacterial secondary metabolites
(Master thesis, 2013)Streptomycete bacteria are a great source of natural bioactive secondary metabolites, some of which are being used as antibiotics and anticancer drugs. Many streptomycetes have the genomic potential for producing 20-30 ... -
Synthetic Biology of Antibiotic Production: Assembly and Re-factoring of Secondary Metabolite Biosynthesis Gene Clusters for Heterologous Expression in Genetically Engineered Bacterial Host
(Master thesis, 2014)The issues in new antibiotic discovery are pressing, because the frequent re-discovery of antibiotic scaffolds leads to few novel antibiotics discovered, besides, with the widespread use of antibacterial agents, multi-resistant ... -
Synthetic biology: Generation of new GFP variants with improved characteristics
(Master thesis, 2015)This project aimed to create new fluorescent protein (FPs) variants using the GFPmut3b, EYFP and mRFP1 through fusing two FPs together. The proximity of these fused FPs was expected to result in altered light absorption ... -
Synthetic Efforts to Investigate Structure-Property Relationships in Dyes for Dye- Sensitized Solar Cells
(Doctoral theses at NTNU;2022:300, Doctoral thesis, 2022)With the backdrop of human-induced global warming in mind, the need for sustainable energy has never been larger. The Intergovernmental Panel on Climate Change presented in their recent assessment report that global warming ... -
Synthetic Efforts to Investigate the Effect of Planarizing the Triarylamine Geometry in Dyes for Dye-Sensitized Solar Cells
(Peer reviewed; Journal article, 2022)The geometry of a dye for dye-sensitized solar cells (DSSCs) has a major impact on its optical and electronic properties. The dye structure also dictates the packing properties and how well the dye insulates the metal–oxide ... -
Synthetic exploration towards total synthesis of Fusolanone B
(Master thesis, 2021)γ-pyronet Fusolanone B (28), tidligere isolert av sopp, har vist potensiale som mulig antibiotika. I dette prosjektet er en retrosyntese inspirert av biosyntese av polyketider blitt utført, og to ulike reaksjonsveier har ... -
Synthetic promoter design and genetic recoding of the chloroplast in Chlamydomonas reinhardtii
(Master thesis, 2020) -
Synthetic strategies towards 4,6-disubstituted pyrrolo[2,3-d]pyrimidines as potential CSF-1R inhibitors
(Master thesis, 2019)Målet med denne masteroppgaven var å syntetisere nye 4,6-disubstituerte pyrrolo[2,3-d]pyrimidiner som hemmere for CSF-1R (”colony stimulating factor 1 receptor”) tyrosinkinase. En ny strategi for syntese av disse er også ... -
Synthetic Strategies Towards 4,6-Disubstituted Pyrrolopyrimidines and Evaluation of their Potential as Colony Stimulating Factor 1 Receptor Kinase Inhibitors
(Doctoral theses at NTNU;2024:60, Doctoral thesis, 2024)Due to their central role in regulating vital cellular processes, protein kinases are increasingly attractive targets in modern drug development. Small molecule drugs have become valuable tools for selectively modulating ... -
Synthetic Strategies towards Imidazopyridinones and 7-Azaoxindoles and their Evaluation as Antibacterial Agents
(Peer reviewed; Journal article, 2021)Imidazopyridinones and 7-azaoxindoles are two classes of heterocyclic compounds with only limited previous use in organic and medicinal chemistry. Various synthetic methods and routes have been evaluated to identify safe ... -
Synthetic Strategies Towards Substituted Purines and Their CSF1R Activity
(Master thesis, 2018)Overexpression of colony stimulating factor 1 (CF1R) has been implicated in a number of disease states, such as cancer, inflammatory disorders and bone disease. Inhibition of the colony stimulating factor 1 receptor kinase ... -
Synthetic Strategies Towards Substituted Pyrrolopyridines as Possible CSF1R Inhibitors
(Master thesis, 2017) -
Synthetic Studies Toward a chemical library of Piperine analogs
(Master thesis, 2022)Kalium 5-hydroksypenta-2,4-dienalsalt ble fremstilt basert på litteraturprosedyrene. Dette fungerer som det første utgangsmaterialet i fem-karbon homologeringsprosessen og amideringsreaksjonene for å gi henholdsvis dienal- ... -
Synthetic Studies Toward Dysoxylactam A
(Master thesis, 2021)Naturproduktet dysoxylactam A (1) ble isolert fra barken av Dysoxylum Hongkongense i 2019 og ble funnet til å være en potent inhibitor av P-gp i kreftceller. Målet for dette master prosjektet var å utvikle en ny tilnærming ... -
Synthetic Studies toward Gold(I)-catalyzed preparation of Trifluoromethyl Compounds
(Master thesis, 2015)In this project gold(I)-catalyzed reactions on triple bonds has been investigated, with the trifluoromethyl group incorporated. Initially the goal was to develop a new gold(I)-catalyzed trifluoromethylation reaction, as ... -
A system for the high-throughput measurement of the shear modulus distribution of human red blood cells
(Peer reviewed; Journal article, 2020)Reduced deformability of red blood cells (RBCs) can affect the hemodynamics of the microcirculation and reduce oxygen transport efficiency. It is also well known that reduced RBC deformability is a signature of various ... -
System Identification of Unmanned Aerial Vehicles
(Master thesis, 2012)The least squares method has been applied to estimate parameters inan aerodynamic model of a simulated aircraft, using data that can beexpected to available from sensors on an Unmanned Aerial Vehicle. Acombination of two ...