Blar i NTNU Open på forfatter "Wendisch, Volker F."
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Characterization of D-arabitol as newly discovered carbon source of Bacillus methanolicus
Lopez, Marina Gil; Irla, Marta Katarzyna; Fernandes de Brito, Luciana; Wendisch, Volker F. (Journal article; Peer reviewed, 2019)Bacillus methanolicus is a Gram-positive, thermophilic, methanol-utilizing bacterium. As a facultative methylotroph, B. methanolicus is also known to utilize D-mannitol, D-glucose and, as recently discovered, sugar alcohol ... -
Corrigendum: Genome-Based Genetic Tool Development for Bacillus methanolicus: Theta- and Rolling Circle-Replicating Plasmids for Inducible Gene Expression and Application to Methanol-Based Cadaverine Production
Irla, Marta Katarzyna; Heggeset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer; Brautaset, Trygve; Wendisch, Volker F. (Journal article; Peer reviewed, 2019) -
Detailed transcriptome analysis of the plant growth promoting Paenibacillus riograndensis SBR5 by using RNA-seq technology
Brito, Luciana Fernandes; Irla, Marta Katarzyna; Kalinowski, Jörn; Wendisch, Volker F. (Journal article; Peer reviewed, 2017)Background The plant growth promoting rhizobacterium Paenibacillus riograndensis SBR5 is a promising candidate to serve as crop inoculant. Despite its potential in providing environmental and economic benefits, the species ... -
Dynamic Co-Cultivation Process of Corynebacterium glutamicum Strains for the Fermentative Production of Riboflavin.
Perez-Garcia, Fernando; Burgardt, Arthur; Kallman, Dina; Wendisch, Volker F.; Bar, Nadav (Journal article, 2021)Residual streams from lignocellulosic processes contain sugar mixtures of glucose, xylose, and mannose. Here, the industrial workhorse Corynebacterium glutamicum was explored as a research platform for the rational utilization ... -
Genome-based genetic tool development for Bacillus methanolicus: Theta-and rolling circle-replicating plasmids for inducible gene expression and application to methanol-based cadaverine production
Irla, Marta; Heggset, Tonje Marita Bjerkan; Nærdal, Ingemar; Paul, Lidia; Haugen, Tone; Le, Simone Balzer; Brautaset, Trygve; Wendisch, Volker F. (Peer reviewed; Journal article, 2016)Bacillus methanolicus is a thermophilic methylotroph able to overproduce amino acids from methanol, a substrate not used for human or animal nutrition. Based on our previous RNA-seq analysis a mannitol inducible promoter ... -
Genomic and Transcriptomic Investigation of the Physiological Response of the Methylotroph Bacillus methanolicus to 5-Aminovalerate
Haupka, Carsten; Fernandes de Brito, Luciana; Busche, Tobias; Wibberg, Daniel; Wendisch, Volker F. (Peer reviewed; Journal article, 2021)The methylotrophic thermophile Bacillus methanolicus can utilize the non-food substrate methanol as its sole carbon and energy source. Metabolism of L-lysine, in particular its biosynthesis, has been studied to some detail, ... -
L-lysine production by Bacillus methanolicus: Genome-based mutational analysis and L-lysine secretion engineering
Nærdal, Ingemar; Netzer, Roman; Irla, Marta; Krog, Anne; Heggset, Tonje Marita Bjerkan; Wendisch, Volker F.; Brautaset, Trygve (Journal article; Peer reviewed, 2017)Bacillus methanolicus is a methylotrophic bacterium with an increasing interest in academic research and for biotechnological applications. This bacterium was previously applied for methanol-based production of l-glutamate, ... -
Metabolic engineering of Corynebacterium glutamicum for de novo production of 3-hydroxycadaverine
Prell, Carina; Vonderbank, Sophie-Ann; Meyer, Florian; Perez-Garcia, Fernando; Wendisch, Volker F. (Peer reviewed; Journal article, 2022)Functionalization of amino acids and their derivatives opens up the possibility to produce novel compounds with additional functional groups, which can expand their application spectra. Hydroxylation of polyamide building ... -
Methanol as a carbon substrate in the bio-economy: metabolic engineering of aerobic methylotrophic bacteria for production of value-added chemicals
Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F. (Journal article; Peer reviewed, 2017)Bacteria are widely used as cell factories for production of enzymes and chemicals, mostly from sugars. Methylotrophic bacteria can utilize the one-carbon compound methanol as sole carbon source for growth, and metabolic ... -
Methanol-based acetoin production by genetically engineered Bacillus methanolicus
Drejer, Eivind Bøe; Chan, Dennis; Haupka, Carsten; Wendisch, Volker F.; Brautaset, Trygve; Irla, Marta Katarzyna (Journal article; Peer reviewed, 2019)Methanol is an attractive alternative non-food feedstock for industrial fermentations that can be used instead of sugar-based raw materials. Here, the thermophilic and methylotrophic bacterium Bacillus methanolicus MGA3 ... -
Methanol-based cadaverine production by genetically engineered Bacillus methanolicus strains
Nærdal, Ingemar; Pfeifenschneider, Johannes; Brautaset, Trygve; Wendisch, Volker F. (Journal article; Peer reviewed, 2015)Methanol is regarded as an attractive substrate for biotechnological production of value-added bulk products, such as amino acids and polyamines. In the present study, the methylotrophic and thermophilic bacterium Bacillus ... -
Methanol-based γ-aminobutyric acid (GABA) production by genetically engineered Bacillus methanolicus strains
Irla, Marta; Nærdal, Ingemar; Brautaset, Trygve; Wendisch, Volker F. (Journal article; Peer reviewed, 2017)The use of methanol as a carbon source for biotechnological processes has recently attracted great interest due to relatively low price, high abundance, high purity of methanol, and the fact that it is a non-food raw ... -
Methanol-essential growth of corynebacterium glutamicum: Adaptive laboratory evolution overcomes limitation due to methanethiol assimilation pathway
Hennig, Guido; Haupka, Carsten; Fernandes de Brito, Luciana; Rückert, Christian; Cahoreau, Edern; Heux, Stéphanie; Wendisch, Volker F. (Peer reviewed; Journal article, 2020)Methanol is a sustainable substrate for biotechnology. In addition to natural methylotrophs, metabolic engineering has gained attention for transfer of methylotrophy. Here, we engineered Corynebacterium glutamicum for ... -
Transaldolase in Bacillus methanolicus: biochemical characterization and biological role in ribulose monophosphate cycle
Pfeifenschneider, Johannes; Markert, Benno; Stolzenberger, Jessica; Brautaset, Trygve; Wendisch, Volker F. (Peer reviewed; Journal article, 2020)Background The Gram-positive facultative methylotrophic bacterium Bacillus methanolicus uses the sedoheptulose-1,7-bisphosphatase (SBPase) variant of the ribulose monophosphate (RuMP) cycle for growth on the C1 carbon ... -
Transcriptome analysis of thermophilic methylotrophic Bacillus methanolicus MGA3 using RNA-sequencing provides detailed insights into its previously uncharted transcriptional landscape
Irla, Marta; Neshat, Armin; Brautaset, Trygve; Rückert, Christian; Kalinowski, Jörn; Wendisch, Volker F. (Journal article; Peer reviewed, 2015)Background Bacillus methanolicus MGA3 is a thermophilic, facultative ribulose monophosphate (RuMP) cycle methylotroph. Together with its ability to produce high yields of amino acids, the relevance of this microorganism ...