Blar i NTNU Open på forfatter "Waugh, Courtney"
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Deregulation of microRNA-155 and its transcription factor NF-kB by polychlorinated biphenyls during viral infection
Waugh, Courtney; Arukwe, Augustine; Jaspers, Veerle (Journal article; Peer reviewed, 2018)Polychlorinated biphenyls (PCBs), and similar environmental contaminants, have been linked to virus outbreaks and increased viral induced mortality since the 1970s. Yet the mechanisms behind this increased susceptibility ... -
Immunomodulation by metals and environmental pollutants in seabirds breeding on Svalbard
Lundgren, Silje Strand (Master thesis, 2018)This master thesis investigated the levels of arsenic, cadmium, chromium, copper, mercury, lead, selenium and zinc in plasma and feathers of black-legged kittiwakes (Rissa tridcatyla) (n = 17), as well as feathers of ... -
Infection with koala retrovirus subgroup B (KoRV-B), but not KoRV-A, is associated with chlamydial disease in free-ranging koalas (Phascolarctos cinereus)
Waugh, Courtney; Hanger, Jon; Loader, Jo; King, Andrew; Hobbs, Mathew; Johnson, Rebecca; Timms, Peter (Journal article; Peer reviewed, 2017)The virulence of chlamydial infection in wild koalas is highly variable between individuals. Some koalas can be infected (PCR positive) with Chlamydia for long periods but remain asymptomatic, whereas others develop clinical ... -
Influence of perfluoroalkyl acids and other parameters on circulating thyroid hormones and immune-related microRNA expression in free-ranging nestling peregrine falcons
Sun, Jiachen; Letcher, Robert J.; Waugh, Courtney; Jaspers, Veerle; Covaci, Adrian; Fernie, Kim (Peer reviewed; Journal article, 2021)Exposure to certain perfluoroalkyl acids (PFAAs) can have considerable effects on the endocrine and immune systems, although such effects remain largely uncharacterized in wildlife. Using an apex avian predator, we ... -
Levels of Perfluoroalkyl and Polyfluoroalkyl Substances (PFASs) in Northern Goshawk (Accipiter gentilis) nestlings from Norway and Spain and potential effect on innate immune system signalling pathways
Castaño Ortiz, Jose Maria (Master thesis, 2018)Per- and polyfluoroalkyl substances (PFASs) are environmentally persistent and bioaccumulative chemicals, which reach high levels in apex predators like birds of prey. Immunomodulation is among the most concerning toxic ... -
No evidence of avian influenza antibodies in two species of raptor nestlings inhabiting Norway
Lee, Megan Marie; Jaspers, Veerle; Løseth, Mari Engvig; Briels, Nathalie; Nygård, Torgeir; Bustnes, Jan Ove; Waugh, Courtney (Journal article; Peer reviewed, 2019)Background: Since 2016, incursions of highly pathogenic avian influenza virus (HPAIV) H5N8 clade 2.3.4.4b have caused unprecedented clinical signs and mortality in white-tailed eagles (WTE; Haliaeetus albicilla) across ... -
PFOS mediates immunomodulation in an avian cell line that can be mitigated via a virus infection
Castaño-Ortiz, Jose M.; Jaspers, Veerle; Waugh, Courtney (Journal article; Peer reviewed, 2019)Background Per- and polyfluoroalkyl substances (PFASs) are environmentally persistent and bioaccumulative chemicals. Immunomodulation is among the most concerning of toxic effects linked with PFAS exposure in mammalian ... -
Prevalence of Chlamydia pecorum in Juvenile Koalas ( Phascolarctos cinereus ) and Evidence for Protection from Infection via Maternal Immunization
Russell, Isabelle; Timms, Peter; Hanger, Jonathan; Loader, Joanne; Gillett, Amber; Waugh, Courtney (Journal article; Peer reviewed, 2018)Chlamydia pecorum in koalas (Phascolarctos cinereus) is considered a sexually transmitted infection. Analysis of samples from koala joeys (<1 yr) suggested that mother-to-young direct transmission was also occurring. ... -
Signals from the south; humpback whales carry messages of Antarctic sea‐ice ecosystem variability
Nash, Susan M. Bengtson; Castrillon, Juliana; Eisenmann, Pascale; Fry, Brian; Shuker, Jon D.; Cropp, Roger A.; Dawson, Amanda; Bignert, Anders; Bohlin-Nizzetto, Pernilla; Waugh, Courtney; Polkinghorne, Bradley J.; Luche, Greta Dalle; McLagan, David (Journal article; Peer reviewed, 2018)Southern hemisphere humpback whales (Megaptera novaeangliae) rely on summer prey abundance of Antarctic krill (Euphausia superba) to fuel one of the longest‐known mammalian migrations on the planet. It is hypothesized that ... -
The Impact of Toxic Elements and Persistent Organic Pollutants on Avian Influenza Prevalence in Arctic Seabirds
Lee, Megan (Master thesis, 2018)As climate change alters northern environments, the dynamics of Arctic disease are predicted to undergo shifts. These shifts may also be influenced by the immunomodulatory properties of anthropogenic contaminants present ... -
Therapeutic effect of a Chlamydia pecorum recombinant major outer membrane protein vaccine on ocular disease in koalas (Phascolarctos cinereus)
Nyari, Sharon; Booth, Rosemary; Quigley, Bonnie L.; Waugh, Courtney; Timms, Peter (Journal article; Peer reviewed, 2019)Chlamydia pecorum is responsible for causing ocular infection and disease which can lead to blindness in koalas (Phascolarctos cinereus). Antibiotics are the current treatment for chlamydial infection and disease in koalas, ...