• A multi-center comparison of vO2peak trainability between interval training and moderate intensity continuous training 

      Williams, Camilla J.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Voisin, Sarah; Li, Zhixiu; Harvey, Nicholas; Croci, Ilaria; Taylor, Jenna L; Gajanand, Trishan; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Pattyn, Nele; Howden, Erin J.; Keating, Shelley E.; Bye, Anja; Stensvold, Dorthe; Wisløff, Ulrik; Papadimitriou, Ioannis; Yan, Xu; Bishop, David J.; Eynon, Nir; Coombes, Jeff S. (Journal article; Peer reviewed, 2019)
      There is heterogeneity in the observed VO2peak response to similar exercise training, and different exercise approaches produce variable degrees of exercise response (trainability). The aim of this study was to combine ...
    • Genome wide association study of response to interval and continuous exercise training: the Predict-HIIT study 

      Williams, Camilla J.; Li, Zhixiu; Harvey, Nicholas; Lea, Rodney A.; Gurd, Brendon J.; Bonafiglia, Jacob T.; Papadimitriou, Ioannis; Jacques, Macsue; Croci, Ilaria; Stensvold, Dorthe; Wisløff, Ulrik; Taylor, Jenna L.; Gajanand, Trishan; Cox, Emily R.; Ramos, Joyce S.; Fassett, Robert G.; Little, Jonathan P.; Francois, Monique E.; Hearon, Christopher M.; Sarma, Satyam; Janssen, Sylvan L.J.E.; Van Craenenbroeck, Emeline M.; Beckers, Paul; Cornelissen, Véronique A.; Howden, Erin J.; Keating, Shelley E.; Yan, Xu; Bishop, David J.; Bye, Anja; Haupt, Larisa M.; Griffiths, Lyn R.; Ashton, Kevin J.; Brown, Matthew A.; Torquati, Luciana; Eynon, Nir; Coombes, Jeff S. (Peer reviewed; Journal article, 2021)
      Background Low cardiorespiratory fitness (V̇O2peak) is highly associated with chronic disease and mortality from all causes. Whilst exercise training is recommended in health guidelines to improve V̇O2peak, there is ...
    • High-Intensity Interval Training in Patients with Heart Failure with Reduced Ejection Fraction 

      Ellingsen, Øyvind; Halle, Martin; Conraads, Viviane; Støylen, Asbjørn; Dalen, Håvard; Delagardelle, Charles; Larsen, Alf Inge; Hole, Torstein; Mezzani, Alessandro; Van Craenenbroeck, Emeline M.; Videm, Vibeke; Beckers, Paul; Christle, Jeffrey W.; Winzer, Ephraim; Mangner, Norman; Woitek, Felix; Höllriegel, Robert; Pressler, Axel; Monk-Hansen, Tea; Snoer, Martin; Feiereisen, Patrick; Valborgland, Torstein; Kjekshus, John; Hambrecht, Rainer; Gielen, Stephan; Karlsen, Trine; Prescott, Eva; Linke, Axel (Journal article; Peer reviewed, 2017)
      Background: Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart ...
    • Iron Deficiency Impacts Diastolic Function, Aerobic Exercise Capacity, and Patient Phenotyping in Heart Failure With Preserved Ejection Fraction: A Subanalysis of the OptimEx-Clin Study 

      Gevaert, Andreas B.; Mueller, Stephan; Winzer, Ephraim B.; Duvinage, André; Van de Heyning, Caroline M.; Pieske-Kraigher, Elisabeth; Beckers, Paul J.; Edelmann, Frank; Wisløff, Ulrik; Pieske, Burkert; Adams, Volker; Halle, Martin; Van Craenenbroeck, Emeline M. (Peer reviewed; Journal article, 2022)
      Aims: Iron deficiency (ID) is linked to reduced aerobic exercise capacity and poor prognosis in patients with heart failure (HF) with reduced ejection fraction (HFrEF); however, data for HF with preserved ejection fraction ...
    • Lifestyle interventions to change trajectories of obesity-related cardiovascular risk from childhood onset to manifestation in adulthood: a joint scientific statement of the task force for childhood health of the European Association of Preventive Cardiology and the European Childhood Obesity Group 

      Hanssen, Henner; Moholdt, Trine; Bahls, Martin; Biffi, Alessandro; Siegrist, Monika; Lewandowski, Adam J.; Biondi-Zoccai, Giuseppe; Cavarretta, Elena; Kokkvoll, Ane Sofie; Løchen, Maja-Lisa; Maestrini, Viviana; Pinto, Rita Salvador; Palermi, Stefano; Thivel, David; Wojcik, Malgorzata; Hansen, Dominique; Van Craenenbroeck, Emeline M.; Weghuber, Daniel; Kraenkel, Nicolle; Tiberi, Monica (Peer reviewed; Journal article, 2023)
      There is an immediate need to optimize cardiovascular (CV) risk management and primary prevention of childhood obesity to timely and more effectively combat the health hazard and socioeconomic burden of CV disease from ...
    • Ubiquitin-proteasome-system and enzymes of energy metabolism in skeletal muscle of patients with HFpEF and HFrEF 

      Adams, Volker; Wunderlich, Sebastian; Mangner, Norman; Hommel, Jennifer; Esefeld, Katrin; Gielen, Stephan; Halle, Martin; Ellingsen, Øyvind; Van Craenenbroeck, Emeline M.; Wisløff, Ulrik; Pieske, Burkert; Linke, Axel; Winzer, Ephraim (Peer reviewed; Journal article, 2021)
      Background Skeletal muscle (SM) alterations contribute to exercise intolerance in heart failure patients with preserved (HFpEF) or reduced (HFrEF) left ventricular ejection fraction (LVEF). Protein degradation via the ...