Blar i NTNU Open på forfatter "Valderhaug, Vibeke Devold"
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Criticality as a measure of developing proteinopathy in engineered human neural networks
Valderhaug, Vibeke Devold; Heiney, Kristine; Huse Ramstad, Ola; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna (Journal article, 2020)A patterned spread of proteinopathy represents a common characteristic of many neurodegenerative diseases. In Parkinson’s disease (PD), misfolded forms of alpha-synuclein proteins aggregate and accumulate in hallmark ... -
Early functional changes associated with alpha-synuclein proteinopathy in engineered human neural networks
Valderhaug, Vibeke Devold; Heiney, Kristine; Huse Ramstad, Ola; Bråthen, Geir; Kuan, Wei-Li; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna (Peer reviewed; Journal article, 2021)A patterned spread of proteinopathy represents a common characteristic of many neurodegenerative diseases. In Parkinson’s disease (PD), misfolded forms of α-synuclein proteins accumulate in hallmark pathological inclusions ... -
Formation of neural networks with structural and functional features consistent with small-world network topology on surface-grafted polymer particles
Valderhaug, Vibeke Devold; Glomm, Wilhelm; Sandru, Eugenia Mariana; Yasuda, Masahiro; Sandvig, Axel; Sandvig, Ioanna (Journal article; Peer reviewed, 2019)In vitro electrophysiological investigation of neural activity at a network level holds tremendous potential for elucidating underlying features of brain function (and dysfunction). In standard neural network modelling ... -
Hallmarks of Criticality in Neuronal Networks Depend on Cell Type and the Temporal Resolution of Neuronal Avalanches
Heiney, Kristine; Valderhaug, Vibeke Devold; Huse Ramstad, Ola; Sandvig, Ioanna; Sandvig, Axel; Nichele, Stefano (Peer reviewed; Journal article, 2021)The human brain has a remarkable capacity for computation, and it has been theorized that this capacity arises from the brain self-organizing into the critical state, a dynamical state poised between ordered and dis- ordered ... -
Method to Obtain Neuromorphic Reservoir Networks from Images of in Vitro Cortical Networks
Mello, Gustavo; Pontes-Filho, Sidney; Sandvig, Ioanna; Valderhaug, Vibeke Devold; Zouganeli, Evi; Huse Ramstad, Ola; Sandvig, Axel; Nichele, Stefano (Chapter, 2020)In the brain, the structure of a network of neurons defines how these neurons implement the computations that underlie the mind and the behavior of animals and humans. Provided that we can describe the network of neurons ... -
Morphological characterization of antennal-lobe projection neurons in the olfactory pathway of heliothine moths
Valderhaug, Vibeke Devold (Master thesis, 2015)The olfactory sensory system is a phylogenetically old system highly important for both the survival and reproduction in most animals. Its organization and function shows striking similarities across phyla, making it ... -
Structural and functional alterations associated with the LRRK2 G2019S mutation revealed in structured human neural networks
Valderhaug, Vibeke Devold; Huse Ramstad, Ola; van de Wijdeven, Rosanne Francisca; Heiney, Kristine; Nichele, Stefano; Sandvig, Axel; Sandvig, Ioanna (Journal article, 2020)Mutations in the LRRK2 gene have been widely linked to Parkinson’s disease. The G2019S variant has been shown to contribute uniquely to both familial and sporadic forms of the disease. LRRK2-related mutations have been ... -
Structural and functional dynamics of healthy and perturbed neuronal networks in vitro
Weir, Janelle Shari (Master thesis, 2019)Rapid advancement in the field of morphogenic neuroengineering has led to interesting research perspectives in the area of in vitro neural network modeling using human induced pluripotent stem cell (hiPSC) derived neural ... -
Structure-function relationships in biological neural networks and the influence of neurodegenerative processes on such dynamics
Valderhaug, Vibeke Devold (Doctoral theses at NTNU;2020:77, Doctoral thesis, 2020) -
Towards Making a Cyborg: A Closed-Loop Reservoir-Neuro System
Aaser, Peter; Knudsen, Martinius; Huse Ramstad, Ola; van de Wijdeven, Rosanne; Nichele, Stefano; Sandvig, Ioanna; Tufte, Gunnar; Bauer, Ulrich Stefan; Halaas, Øyvind; Hendseth, Sverre; Sandvig, Axel; Valderhaug, Vibeke Devold (Chapter; Peer reviewed, 2017)The human brain is a remarkable computing machine, i.e. vastly parallel, self-organizing, robust, and energy efficient. To gain a better understanding into how the brain works, a cyborg (cybernetic organism, a combination ...