Blar i NTNU Open på forfatter "Tian, Erming"
-
An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells
Sousa, Mirta; Zub, Kamila Anna; Aas, Per Arne; Hanssen-Bauer, Audun; Demirovic, Aida; Sarno, Antonio; Tian, Erming; Liabakk, Nina-Beate; Slupphaug, Geir (Journal article; Peer reviewed, 2013)Alterations in checkpoint and DNA repair pathways may provide adaptive mechanisms contributing to acquired drug resistance. Here, we investigated the levels of proteins mediating DNA damage signaling and -repair in RPMI8226 ... -
Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro
Våtsveen, Thea Kristin; Sponaas, Anne Marit; Tian, Erming; Zhang, Qing; Misund, Kristine; Sundan, Anders; Børset, Magne; Waage, Anders; Brede, Gaute (Journal article; Peer reviewed, 2016)Background: Multiple myeloma is an incurable complex disease characterized by clonal proliferation of malignant plasma cells in a hypoxic bone marrow environment. Hypoxia-dependent erythropoietin (EPO)-receptor (EPOR) ... -
Identification of the source of elevated hepatocyte growth factor levels in multiple myeloma patients
Rampa, Christoph Samuel; Tian, Erming; Våtsveen, Thea Kristin; Buene, Glenn; Slørdahl, Tobias Schmidt; Børset, Magne; Waage, Anders; Sundan, Anders (Journal article; Peer reviewed, 2014)Background Hepatocyte growth factor (HGF) is a pleiotropic cytokine which can lead to cancer cell proliferation, migration and metastasis. In multiple myeloma (MM) patients it is an abundant component of the bone marrow. ... -
The Genetic Impacts in the Oncogenesis of Multiple Myeloma
Tian, Erming (Doktoravhandlinger ved NTNU, 1503-8181; 2008:288, Doctoral thesis, 2008)The Genetic Impacts in the Oncogenesis of Multiple Myeloma “Genenes innvirkning på onkogenesen av myelomatose” Myelomatose er kreft i plasmaceller, som er sluttstadiet i utviklingen av B-cellene, de immunglobulinproduserende ...