Browsing NTNU Open by Author "Stubhaug, Audun"
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A tonic heat test stimulus yields a larger and more reliable conditioned pain modulation effect compared to a phasic heat test stimulus
Lie, Marie; Matre, Dagfinn; Hansson, Per; Stubhaug, Audun; Zwart, John-Anker; Nilsen, Kristian Bernhard (Journal article; Peer reviewed, 2017)Introduction: The interest in conditioned pain modulation (CPM) as a clinical tool for measuring endogenously induced analgesia is increasing. There is, however, large variation in the CPM methodology, hindering comparison ... -
Absorption and pharmacokinetics of bupivacaine after bilateral topical administration in tonsillar fossae for posttonsillectomy pain relief
Berg, Kristin Sandal; Seines, Ellisiv; Gál, Peter; Løberg-Emanuelsen, Lise; Stubhaug, Audun; Nielsen, Erik Waage; Spigset, Olav (Journal article; Peer reviewed, 2024)No previous studies have investigated the systemic absorption of bupivacaine when used topically for posttonsillectomy pain. The present study was undertaken to investigate the pharmacokinetics of bupivacaine after ... -
A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain
Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Peer reviewed; Journal article, 2022)Objectives - To examine the possible bidirectional association between insomnia and comorbid chronic low back pain (LBP) and lower limb pain and to explore whether high-sensitivity C-reactive protein (hsCRP) amplifies these ... -
A bidirectional study of the association between insomnia, high-sensitivity C-reactive protein, and comorbid low back pain and lower limb pain
Ho, Kevin Kwan Ngai; Skarpsno, Eivind S.; Nilsen, Kristian Bernhard; Ferreira, Paulo Herrique; Pinheiro, Marina; Hopstock, Laila Arnesdatter; Johnsen, Marianne Bakke; Steingrímsdóttir, Ólöf Anna; Nielsen, Christopher Sivert; Stubhaug, Audun; Simic, Milena (Journal article; Peer reviewed, 2022) -
Comparing objective cognitive impairments in patients with peripheral neuropathic pain or fibromyalgia
Jacobsen, Henrik Børsting; Stiles, Tore C; Stubhaug, Audun; Landrø, Nils Inge; Hansson, Per (Peer reviewed; Journal article, 2021)Existing studies on cognitive impairments in chronic pain do not investigate peripheral neuropathic pain (PNP) or compare pain conditions in a satisfactory manner. Here we aimed to compare executive dysfunctions in PNP ... -
Improvement in Psoriasis Area and Severity Index Score predicts improvement in skin pain over time in patients with psoriasis
Ljoså, Tone Marte; Stubhaug, Audun; Mørk, Cato; Moum, Torbjørn Åge; Wahl, Astrid Klopstad (Journal article; Peer reviewed, 2013)Pain and discomfort are common and often severe skin symptoms in patients with psoriasis. However, no studies have investigated skin pain and discomfort over time, or factors that explain changes in these symptoms. The ... -
Neuropsychological functions of verbal recall and psychomotor speed significantly affect pain tolerance
Jacobsen, Henrik Børsting; Stubhaug, Audun; Schirmer, Henrik; Landrø, Nils Inge; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Nielsen, Christopher Sivert (Peer reviewed; Journal article, 2019)Background: Effects from cognitive performance on pain tolerance have been documented, however, sample sizes are small and confounders often overlooked. We aimed to establish that performance on neuropsychological tests ... -
Pilot field testing of the chronic pain classification for ICD-11: The results of ecological coding
Barke, Antonia; Korwisi, Beatrice; Casser, Hans-Raimund; Fors, Egil Andreas; Geber, Christian; Schug, Stephan A.; Stubhaug, Audun; Ushida, Takahiro; Wetterling, Thomas; Rief, Winfried; Treede, Rolf-Detlef (Journal article; Peer reviewed, 2018)Background A task force of the International Association for the Study of Pain (IASP) has developed a classification of chronic pain for the ICD-11 consisting of seven major categories. The objective was to test whether ... -
Predicting the outcome of persistent sciatica using conditioned pain modulation: 1-year results from a prospective cohort study
Fjeld, Olaf Randall; Grotle, Margreth; Matre, Dagfinn; Pedersen, Linda Margareth; Lie, Marie; Småstuen, Milada Cvancarova; Storheim, Kjersti; Heuch, Ingrid; Stubhaug, Audun; Zwart, John-Anker; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2019)Background and aims Recovery in patients hospitalised with severe sciatica is unpredictable. Prognostic tools to aid clinicians in the early identification of patients at risk of developing chronic sciatic pain are warranted. ... -
Recommendations on practice of conditioned pain modulation (CPM) testing
Yarnitsky, D.; Bouhassira, D.; Drewes, A.M.; Filingim, R.B.; Granot, M.; Hansson, Per; Landau, R.; Marchand, S.; Matre, Dagfinn; Stubhaug, Audun; Nilsen, Kristian Bernhard; Treede, R.D.; Wilder-Smith, O.H.G. (Peer reviewed; Journal article, 2015)Protocols for testing conditioned pain modulation (CPM) vary betweendifferent labs/clinics. In order to promote research and clinical applicationof this tool, we summarize the recommendations of interested researchersconsensus ...