Browsing NTNU Open by Author "Størkersen, Øystein"
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18F-Fluciclovine PET/MRI for preoperative lymph node staging in high-risk prostate cancer patients
Selnæs, Kirsten Margrete; Krüger-Stokke, Brage; Elschot, Mattijs; Willoch, Frode; Størkersen, Øystein; Sandsmark, Elise; Moestue, Siver Andreas; Tessem, May-Britt; Halvorsen, Dag; Kjøbli, Eirik; Angelsen, Anders; Langørgen, Sverre; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2018)Objective To investigate the diagnostic potential of simultaneous 18F-fluciclovine PET/MRI for pelvic lymph node (LN) staging in patients with high-risk prostate cancer. Methods High-risk prostate cancer patients (n=28) ... -
A PET/MRI study towards finding the optimal [18F]Fluciclovine PET protocol for detection and characterisation of primary prostate cancer.
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Tessem, May-Britt; Moestue, Siver Andreas; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2016)Purpose: [18F]Fluciclovine PET imaging shows promise for the assessment of prostate cancer. The purpose of this PET/MRI study is to optimise the PET imaging protocol for detection and characterisation of primary prostate ... -
Combined 18F-Fluciclovine PET/MRI shows potential for detection and characterization of high-risk prostate cancer
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Giskeødegård, Guro F.; Tessem, May-Britt; Moestue, Siver Andreas; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2017)The objective of this study is to investigate if quantitative imaging features derived from combined 18F-Fluciclovine Positron Emission Tomograpy (PET) / multiparametric Magnetic Resonance Imaging (MRI) show potential for ... -
Diffusion-weighted MRI for early detection and characterization of prostate cancer in the transgenic adenocarcinoma of the mouse prostate model
Hill, Deborah Katherine; Kim, Eugene; Teruel, Jose Ramon; Jamin, Yann; Widerøe, Marius; Søgaard, Caroline Danielsen; Størkersen, Øystein; Nava Rodriguez, Daniel; Heindl, Andreas; Yuan, Yinyin; Bathen, Tone Frost; Moestue, Siver Andreas (Journal article; Peer reviewed, 2016)Purpose To improve early diagnosis of prostate cancer to aid clinical decision-making. Diffusion-weighted magnetic resonance imaging (DW-MRI) is sensitive to water diffusion throughout tissues, which correlates with ... -
Disease-specific outcomes of Radical Prostatectomies in Northern Norway; A case for the impact of perineural infiltration and postoperative PSA-doubling time
Andersen, Sigve; Richardsen, Elin; Nordby, Yngve; Ness, Nora; Størkersen, Øystein; Al-Shibli, Khalid; Dønnem, Tom; Bertilsson, Helena; Busund, Lill-Tove; Angelsen, Anders; Bremnes, Roy M. (Journal article; Peer reviewed, 2014)Background: Prostate cancer is the most common male malignancy and a mayor cause of mortality in the western world. The impact of clinicopathological variables on disease related outcomes have mainly been reported from a ... -
En bloc radical cystectomy: An overview of the technique and oncological results
Kjøbli, Eirik; Salvesen, Øyvind Olav; Langørgen, Sverre; Størkersen, Øystein; Wibe, Arne; Arum, Carl-Jørgen (Journal article; Peer reviewed, 2022)Objectives To reduce recurrence after radical cystectomy (RC), we developed a technique based on the principles of the circumferential resection margin used during total mesorectal excision for rectal cancer, namely, en ... -
Impact of prebiopsy MRI on prostate cancer staging: Results from the Norwegian Prostate Cancer Registry
Haug, Erik Skaaheim; Myklebust, Tor Åge; Juliebø-Jones, Patrick; Reisæter, Lars Anders Rokne; Aas, Kirsti; Berg, Arne Stenrud; Muller, Christoph Rainer; Hofmann, Bjørn Morten; Størkersen, Øystein; Nilsen, Kim L.; Johannessen, Tom Børge; Beisland, Christian (Peer reviewed; Journal article, 2023)The aim of this study is to evaluate the 2015 introduction of prebiopsy magnetic resonance imaging of the prostate (MRI-P) as the standard of care for diagnosing prostate cancer (PCa) by the Norwegian public health care ... -
Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma
Andersen, Maria Karoline; Rise, Kjersti; Giskeødegård, Guro F.; Richardsen, Elin; Bertilsson, Helena; Størkersen, Øystein; Bathen, Tone Frost; Rye, Morten Beck; Tessem, May-Britt (Journal article; Peer reviewed, 2018)Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive tumors. The aim of this study was to detect differentially ... -
Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migration
Vandsemb, Esten Nymoen; Bertilsson, Helena; Abdollahi, Pegah; Størkersen, Øystein; Våtsveen, Thea Kristin; Rye, Morten Beck; Rø, Torstein Baade; Børset, Magne; Slørdahl, Tobias Schmidt (Journal article; Peer reviewed, 2016)Background: PRL-3 is a phosphatase implicated in oncogenesis in multiple cancers. In some cancers, notably carcinomas, PRL-3 is also associated with inferior prognosis and increased metastatic potential. In this study we ... -
Prediction of recurrence from metabolites and expression of TOP2A and EZH2 in prostate cancer patients treated with radiotherapy
Hansen, Ailin Falkmo; Høiem, Therese Stork; Selnæs, Kirsten Margrete; Bofin, Anna M.; Størkersen, Øystein; Bertilsson, Helena; Wright, Alan J.; Giskeødegård, Guro F.; Bathen, Tone Frost; Rye, Morten Beck; Tessem, May-Britt (Peer reviewed; Journal article, 2023)Background The dual upregulation of TOP2A and EZH2 gene expression has been proposed as a biomarker for recurrence in prostate cancer patients to be treated with radical prostatectomy. A low tissue level of the metabolite ...