Browsing NTNU Open by Author "Sliwka, Hans-Richard"
Now showing items 1-7 of 7
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Cationic polyene phospholipids as DNA carriers for ocular gene therapy
Machado, Susana; Calado, Sofia; Bitoque, Diogo; Oliveira, Ana Vanessa; Øpstad, Christer Lorentz; Zeeshan, Muhammad; Sliwka, Hans-Richard; Partali, Vassilia; Pungente, Michael; Silva, Gabriela (Journal article; Peer reviewed, 2014)Recent success in the treatment of congenital blindness demonstrates the potential of ocular gene therapy as a therapeutic approach. The eye is a good target due to its small size, minimal diffusion of therapeutic agent ... -
Detecting commercial fraud in Atlantic salmon (Salmo salar) using NMR spectroscopy
Møller, Ida Aksland (Master thesis, 2018)One way to preserve food is to freeze it, and today, frozen food is cheaper than fresh food. Because of this difference in value, the food industry can see economic benefits in misleading the consumer by labelling frozen-thawed ... -
Key to xenobiotic carotenoids
Sliwka, Hans-Richard; Partali, Vassilia (Journal article; Peer reviewed, 2012)A listing of carotenoids with heteroatoms (X = F, Cl, Br, I, Si, N, S, Se, Fe) directly attached to the carotenoid carbon skeleton has been compiled. The 178 listed carotenoids with C,H,X atoms demonstrate that the ... -
Novel cationic carotenoid lipids as delivery vectors of antisense oligonucleotides for exon skipping in duchenne muscular dystrophy
Popplewell, Linda; Abu-Dayya, Aseel; Khanna, Tushar; Flinterman, Marcella; Abdul Khalique, nada; Raju, Liji; Øpstad, Christer Lorentz; Sliwka, Hans-Richard; Partali, Vassilia; Dickson, George; Pungente, Michael (Journal article; Peer reviewed, 2012)Duchenne Muscular Dystrophy (DMD) is a common, inherited, incurable, fatal muscle wasting disease caused by deletions that disrupt the reading frame of the DMD gene such that no functional dystrophin protein is produced. ... -
Syntheses and properties of long chain polyenes - Syntheses and properties of cationic and anionic polyene lipids
Zeeshan, Muhammad (Doctoral Theses at NTNU, 1503-8181; 2012-271, Doctoral thesis, 2012) -
Synthesis and preliminary investigations of the siRNA delivery potential of novel, single-chain rigid cationic carotenoid lipids
Pungente, Michael; Jubeli, Emile; Øpstad, Christer Lorentz; Al-Kawaz, Mais; Barakat, Nour; Ibrahim, Tarek; Abdul Khalique, Nada; Raju, Liji; Jones, Rachel; Leopold, Philip; Sliwka, Hans-Richard; Partali, Vassilia (Journal article; Peer reviewed, 2012)The success of nucleic acid delivery requires the development of safe and efficient delivery vectors that overcome cellular barriers for effective transport. Herein we describe the synthesis of a series of novel, ... -
Synthesis of conjugated unsaturated Amino Acids
Buvik, Vanja (Master thesis, 2016)Of the three main groups of biomolecules - lipids, carbohydrates and proteins - lipids and carbohydrates containing polyene functionalities have already been investigated. This thesis describes a first approach to the ...