Blar i NTNU Open på forfatter "Nyrnes, Siri Ann"
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Assessment of Early Diastolic Intraventricular Pressure Difference in Children by Blood Speckle-Tracking Echocardiography
Sørensen, Kristian; Fadnes, Solveig; Mertens, Luc; Henry, Matthew; Segers, Patrick; Løvstakken, Lasse; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2023)Background: The lack of reliable echocardiographic techniques to assess diastolic function in children is a major clinical limitation. Our aim was to develop and validate the intraventricular pressure difference (IVPD) ... -
Blood Speckle-Tracking Based on High–Frame Rate Ultrasound Imaging in Pediatric Cardiology
Nyrnes, Siri Ann; Fadnes, Solveig; Wigen, Morten Smedsrud; Mertens, Luc; Løvstakken, Lasse (Peer reviewed; Journal article, 2020)Background: Flow properties play an important role in cardiac function, remodeling, and morphogenesis but cannot be displayed in detail with today’s echocardiographic techniques. The authors hypothesized that blood ... -
Cardiac function in newborns of obese women and the effect of exercise during pregnancy. A randomized controlled trial
Nyrnes, Siri Ann; Garnæs, Kirsti Krohn; Salvesen, Øyvind; Timilsina, Anita Sharma; Moholdt, Trine; Ingul, Charlotte Bjørk (Journal article; Peer reviewed, 2018)Background The prevalence of maternal obesity is rising. Pre-pregnancy obesity is associated with later cardiovascular disease in the child and the underlying pathogenesis begins in early life. Therefore, pregnancy and ... -
Continuous monitoring of cerebral blood flow during general anaesthesia in infants
Vik, Sigrid Dannheim; Torp, Hans Garman; Jarmund, Anders Hagen; Kiss, Gabriel Hanssen; Follestad, Turid; Støen, Ragnhild; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2023)Background: General anaesthesia is associated with neurocognitive deficits in infants after noncardiac surgery. Disturbances in cerebral perfusion as a result of systemic hypotension and impaired autoregulation may be a ... -
Detailed flow visualization in fetal and neonatal hearts using 2-D speckle tracking
Fadnes, Solveig; Nyrnes, Siri Ann; Wigen, Morten Smedsrud; Tegnander, Eva; Løvstakken, Lasse (Journal article, 2016)Two-dimensional blood speckle tracking has shown promise for measuring the complex flow patterns in neonatal hearts when based on linear array and high-frame-rate plane wave imaging. For phased array pediatric imaging, ... -
Detection of Cerebral High-Intensity Transient Signals by NeoDoppler during Cardiac Catheterization and Cardiac Surgery in Infants
Leth-Olsen, Martin; Døhlen, Gaute; Torp, Hans; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2022)There is a risk of gaseous and solid micro-embolus formation during transcatheter cardiac interventions and surgery in children with congenital heart disease (CHD). Our aim was to study the burden of high-intensity transient ... -
Effect of supervised exercise training during pregnancy on neonatal and maternal outcomes among overweight and obese women. Secondary analyses of the ETIP trial: A randomised controlled trial
Garnæs, Kirsti Krohn; Nyrnes, Siri Ann; Salvesen, Kjell Å; Salvesen, Øyvind; Mørkved, Siv; Moholdt, Trine (Journal article; Peer reviewed, 2017)Background Maternal obesity associates with complications during pregnancy and childbirth. Our aim was to investigate if exercise during pregnancy in overweight/obese women could influence birth weight or other neonatal ... -
Effects of tilt on cerebral hemodynamics measured by NeoDoppler in healthy neonates
Jarmund, Anders Hagen; Ødegård, Siv Steinsmo; Torp, Hans; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2021)Background: Today, there are conflicting descriptions of how neonates respond to tilt. Examining physiologic responses of cerebral blood flow velocities (BFVs) in challenging situations like a tilt requires equipment that ... -
Femoral nailing associated with bone marrow emboli in pigs induced a specific increase in blood IL-6 and broad inflammatory responses in the heart and lungs
Kristiansen, Steinar; Storm, Benjamin Stage; Emblem, Åse; Grønli, Renathe Henriksen; Pettersen, Kristin; Hilmo, Jonas Larsen; Jarmund, Anders Hagen; Leth-Olsen, Martin; Nyrnes, Siri Ann; Nilsen, Bent Aksel; Nielsen, Erik Waage; Mollnes, Tom Eirik (Journal article; Peer reviewed, 2024)Introduction: Bone marrow embolization may complicate orthopedic surgery, potentially causing fat embolism syndrome. The inflammatory potential of bone marrow emboli is unclear. We aimed to investigate the inflammatory ... -
Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain
Kristiansen, Steinar; Jarmund, Anders Hagen; Hilmo, Jonas Larsen; Mollnes, Tom Eirik; Leth-Olsen, Martin; Nyrnes, Siri Ann; Nilsen, Bent Aksel; Grønli, Renathe Henriksen; Faldaas, Bjørn Ove; Storm, Benjamin Stage; Espenes, Arild; Nielsen, Erik Waage (Journal article; Peer reviewed, 2024)Background: Shaft fractures of the femur are commonly treated with intramedullary nailing, which can release bone marrow emboli into the bloodstream. Emboli can travel to the lungs, impairing gas exchange and causing ... -
In vivo intracardiac vector flow imaging using phased array transducers for pediatric cardiology
Fadnes, Solveig; Wigen, Morten Smedsrud; Nyrnes, Siri Ann; Løvstakken, Lasse (Journal article; Peer reviewed, 2017)Two-dimensional blood speckle tracking (ST) has shown promise for measuring complex flow patterns in neonatal hearts using linear arrays and high-frame-rate plane wave imaging. For general pediatric applications, however, ... -
Instant Detection of Cerebral Blood Flow Changes in Infants with Congenital Heart Disease during Transcatheter Interventions
Leth-Olsen, Martin; Døhlen, Gaute; Torp, Hans; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2024)Background: Transcatheter interventions are increasingly used in children with congenital heart disease. However, these interventions can affect cardiac output and cerebral circulation. In this pilot study, we aimed to ... -
Live born recipient of twin-twin transfusion syndrome with anomalous mitral arcade
Ødegård, Siv Steinsmo; Kahrs, Birgitte Heiberg; Lang, Astri Maria; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2019)We present a case report of anomalous mitral arcade in a live born former recipient of twin-twin transfusion syndrome. At 33+0 week of gestation fetal ultrasound demonstrated that she had a large mitral insufficiency, ... -
Low frequency cerebral arterial and venous flow oscillations in healthy neonates measured by NeoDoppler
Ødegård, Siv Steinsmo; Torp, Hans; Follestad, Turid; Leth-Olsen, Martin; Støen, Ragnhild; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2022)Background: A cerebroprotective effect of low frequency oscillations (LFO) in cerebral blood flow (CBF) has been suggested in adults, but its significance in neonates is not known. This observational study evaluates normal ... -
NeoDoppler: New ultrasound technology for continous cerebral circulation monitoring in neonates.
Vik, Sigrid Dannheim; Torp, Hans; Follestad, Turid; Støen, Ragnhild; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2019)BACKGROUND: There is a strong need for continuous cerebral circulation monitoring in neonatal care, since suboptimal cerebral blood flow may lead to brain injuries in preterm infants and other critically ill neonates. ... -
New ultrasound flow modalities for evaluation of congenital heart defects
Nyrnes, Siri Ann (Doktoravhandlinger ved NTNU, 1503-8181; 2014:275, Doctoral thesis, 2014) -
Perioperative Detection of Cerebral Fat Emboli From Bone Using High-Frequency Doppler Ultrasound
Jarmund, Anders Hagen; Kristiansen, Steinar; Leth-Olsen, Martin; Vogt, Ella Christina Stray; Nervik, Ingunn; Torp, Hans; Nielsen, Erik Waage; Nyrnes, Siri Ann (Peer reviewed; Journal article, 2024) -
Pulmonary Hypertension in Children is associated with Abnormal Flow patterns in the Main Pulmonary Artery as demonstrated by Blood Speckle Tracking
Mawad, Wadi; Fadnes, Solveig; Løvstakken, Lasse; Henry, Matthew; Mertens, Luc; Nyrnes, Siri Ann (Journal article; Peer reviewed, 2022)Background Paediatric pulmonary arterial hypertension (PAH) is characterized by increased pulmonary vascular resistance resulting in increased pulmonary artery (PA) and right ventricular pressure (RV). This is associated ... -
Randomised controlled trial of preconception lifestyle intervention on maternal and offspring health in people with increased risk of gestational diabetes: study protocol for the BEFORE THE BEGINNING trial
Sujan, Md Abu Jafar; Skarstad, Hanna Margrethe Storheil; Rosvold, Guro; Fougner, Stine Lyngvi; Nyrnes, Siri Ann; Iversen, Ann-Charlotte; Follestad, Turid; Salvesen, Kjell Åsmund Blix; Moholdt, Trine (Peer reviewed; Journal article, 2023)Introduction: Gestational diabetes mellitus (GDM) is associated with increased risk for type 2 diabetes in the mother and cardiometabolic diseases in the child. The preconception period is an optimal window to adapt the ... -
Right ventricular energetics using blood speckle tracking in pediatric congenital heart disease
Mawad, Wadi (Doctoral theses at NTNU;2024:190, Doctoral thesis, 2024)This thesis is composed of three studies of right ventricular (RV) energetics in pediatric patients with congenital heart disease (CHD), using blood speckle tracking (BST). The objectives were to describe the RV energetics ...