Blar i NTNU Open på forfatter "Nygaard, Unni Cecilie"
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Carbon nanofibers have IgE adjuvant capacity but are less potent than nanotubes in promoting allergic airway responses
Nygaard, Unni Cecilie; Samuelsen, Mari; Marioara, Calin Daniel; Løvik, Martinus (Journal article; Peer reviewed, 2013)There is a growing concern for the possible health impact of nanoparticles. The main objective of this study was to investigate the allergy-promoting capacity of four different carbon nanofiber (CNF) samples in an injection ... -
Cry1Ab Protein from Bacillus thuringiensis and MON810 cry1Ab-transgenic Maize Exerts No Adjuvant Effect After Airway Exposure
Andreassen, Monica; Bøhn, Thomas; Wikmark, Odd Gunnar; van den Berg, Johnnie; Løvik, Martinus; Traavik, Terje; Nygaard, Unni Cecilie (Journal article; Peer reviewed, 2015)The genetically modified (GM) maize event MON810 has been inserted with a processed version of the transgene, cry1Ab, derived from the soil bacterium Bacillus thuringiensis (Bt) to express proteins with insecticidal ... -
Early combination of material characteristics and toxicology is useful in the design of low toxicity carbon nanofiber
Jensen, Ellen K; Larsen, Sten Yngve; Nygaard, Unni Cecilie; Marioara, Calin Daniel; Syversen, Tore (Journal article; Peer reviewed, 2012)This paper describes an approach for the early combination of material characterization and toxicology testing in order to design carbon nanofiber (CNF) with low toxicity. The aim was to investigate how the adjustment of ... -
Exposure to bisphenol A, but not phthalates, increases spontaneous diabetes type 1 development in NOD mice
Bodin, Johanna; Bølling, Anette Kocbach; Wendt, Anna; Eliasson, Lena; Becher, Rune; Kuper, Frieke; Løvik, Martinus; Nygaard, Unni Cecilie (Journal article; Peer reviewed, 2015)Type 1 diabetes mellitus (T1DM) is an autoimmune destruction of insulin producing pancreatic beta-cells due to a genetic predisposition and can be triggered by environmental factors. We have previously shown that bisphenol ... -
Humoral and cellular immune responses in mice after airway administration of Bacillus thuringiensis Cry1Ab and MON810 cry1Ab-transgenic maize
Andreassen, Monica; Rocca, Elena; Bøhn, Thomas; Wikmark, Odd Gunnar; van der Berg, Johnnie; Løvik, Martinus; Traavik, Terje; Nygaard, Unni Cecilie (Journal article; Peer reviewed, 2014)Genetically modified (GM) crops may bring new proteins with immunogenic and allergenic properties into the food and feed chains. The most commonly grown GM maize, MON810 expresses a modified version of the insecticidal ... -
Immune cell profiles associated with exposure to phthalates (DEHP and DiNP) - A high-dimensional cell cytometry (CyTOF) approach
Ulriksen, Emilie Steinbakk (Master thesis, 2019)Bakgrunn: Forekomsten av immunrelaterte sykdommer har i løpet av de siste tiårene økt for personer som lever i den vestlige verden. Denne økningen, kan delvis skyldes økt eksponering fra kjemikalier fra hverdags produkter ... -
Investigations of immunogenic, allergenic and adjuvant properties of Cry1Ab protein after intragastric exposure in a food allergy model in mice
Andreassen, Monica; Bøhn, Thomas; Wikmark, Odd-Gunnar; Bodin, Johanna; Traavik, Terje; Løvik, Martinus; Nygaard, Unni Cecilie (Journal article; Peer reviewed, 2016-05-04)Background: In genetically modified (GM) crops there is a risk that the inserted genes may introduce new allergens and/or adjuvants into the food and feed chain. The MON810 maize, expressing the insecticidal Cry1Ab toxin, ...