Blar i NTNU Open på forfatter "Nilsen, Nadra"
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A role for the adaptor proteins TRAM and TRIF in toll-like receptor 2 signaling
Nilsen, Nadra; Gregory I., Vladimer; Stenvik, Jørgen; Ørning, Mathias Pontus; Zeid-Kilani, Maria Vanessa; Bugge, Marit; Bergstrøm, Bjarte; Conlon, Joseph; Husebye, Harald; Amy, Hise; Fitzgerald, Katherine A.; Espevik, Terje; Lien, Egil (Journal article; Peer reviewed, 2015)Toll-like receptors (TLRs) are involved in sensing invading microbes by host innate immunity. TLR2 recognizes bacterial lipoproteins/lipopeptides, and lipopolysaccharide activates TLR4. TLR2 and TLR4 signal via the ... -
Characterization of in vitro polarized human neutrophils - a model for testing how cancer cells affect neutrophil polarization
Seljeseth, Emilie (Master thesis, 2021)Nøytrofile er de mest tallrike leukocyttene i den menneskelige sirkulasjonen og de første cellene som rekrutteres til infeksjons- og betennelsessteder. Disse medfødte immuncellene er hovedaktører i vertsimmuniteten og har ... -
Detecting Toll-Like Receptor 8
Mevatne, Sebastian (Master thesis, 2020)Toll-lignende reseptorer (TLR)er er reseptorer i det iboende immunsystemet som kan binde et bredt utvalg av mikrobe-tilknyttede molekylære mønstre (MAMP)s. Ved deres aktivering, utløses et bredt spekter av cellulære ... -
Enhanced expression of CXCL10 in inflammatory bowel disease: Potential role of mucosal toll-like 3 receptor stimulation
Østvik, Ann Elisabet; Granlund, Atle; Bugge, Marit; Nilsen, Nadra; Torp, Sverre Helge; Waldum, Helge; Damås, Jan Kristian; Espevik, Terje; Sandvik, Arne Kristian (Journal article, 2013)We explored the gene expression in colonic biopsies of active and inactive inflammatory bowel disease (IBD), in an extensive material of ulcerative colitis (UC) and Crohn`s disease (CD). The chemokine CXCL10 and its receptor ... -
Induction of Inflammatory Chemokines: RANTES/CCL5, MCP-1/CCL2 and MIP-1β/CCL4 in Response to Toll-Like Receptor 2 Agonists
Shuja, Afsheen (Master thesis, 2012)Toll-Like Receptors (TLRs) belong to signaling class of pattern recognition receptors (PRRs) and are involved in the recognition of invariant pathogen associated molecular patterns (PAMPs), which are not found in vertebrates. ... -
Investigation of Pattern Recognition Receptor Expression and Cytokine Responses in CAL-1 and PMDC05 cell lines and human Plasmacytoid Dendritic Cells (pDCs)
Lau, Eileen (Master thesis, 2022)Abstract will be available on 2027-06-30 -
Metastatic Cancerous Intestinal Epithelial Cells express Toll-like receptor 3 and release RANTES/CCL5 and IP-10/CXCL10 in response to Double-stranded RNA
Bugge, Marit (Master thesis, 2011)Toll-like receptors (TLR)s are important for mounting an inflammatory response against invading microorganisms by recognizing pathogen-associated molecular patterns (PAMP)s, which are rare or absent in vertebrates. TLRs ... -
Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele
Etokebe, GE; Skjeldal, F; Nilsen, Nadra; Rodionov, Dmitrii; Knezevic, Jelena; Bulat-Kardum, Ljiljana; Espevik, Terje; Bakke, Oddmund; Dembic, Zlatko (Peer reviewed; Journal article, 2010)We have sequenced 416 Toll‐like receptor‐2 (TLR2) alleles in 208 subjects in a tuberculosis case–control study in Croatian Caucasian population. We found ten single nucleotide polymorphisms (SNP) among which three were ... -
Toll-Like Receptor 3 Signaling in Intestinal Epithelial Cells
Bugge, Marit (Doctoral thesis at NTNU;2016:77, Doctoral thesis, 2016)Toll-lignende reseptor 3 uttrykk og signalisering i kolonepitelceller: Toll-lignende reseptorer (TLRer) er viktige sensorer i menneskets medfødte immunforsvar og aktiveres av komponenter som representerer fare for verten, ...