• Automated Quantification of Human Osteoclasts Using Object Detection 

      Kohtala, Sampsa; Nedal, Tonje Marie Vikene; Carlo, Kriesi; Moen, Siv Helen; Ma, Qianli; Ødegaard, Kristin Sirnes; Standal, Therese; Steinert, Martin (Peer reviewed; Journal article, 2022)
      A balanced skeletal remodeling process is paramount to staying healthy. The remodeling process can be studied by analyzing osteoclasts differentiated in vitro from mononuclear cells isolated from peripheral blood or from ...
    • Comprehensive small RNA-sequencing of primary myeloma cells identifies miR-105-5p as a predictor of patient survival 

      Aass, Kristin Roseth; Nedal, Tonje Marie Vikene; Bouma, Siri Anshushaug; Tryggestad, Synne Stokke; Haukås, Einar; Slørdahl, Tobias Schmidt; Waage, Anders; Standal, Therese; Mjelle, Robin (Journal article; Peer reviewed, 2022)
    • IL-32 is induced by activation of toll-like receptors in multiple myeloma cells 

      Aass, Kristin Roseth; Tryggestad, Synne Stokke; Mjelle, Robin; Kastnes, Martin Haugrud; Nedal, Tonje Marie Vikene; Misund, Kristine; Standal, Therese (Peer reviewed; Journal article, 2023)
      Multiple myeloma (MM) is a hematological cancer characterized by accumulation of malignant plasma cells in the bone marrow. The patients are immune suppressed and suffer from recurrent and chronic infections. Interleukin-32 ...
    • Interactions between adipocytes and cancer cells in multiple myeloma 

      Rødningen, Eline (Master thesis, 2022)
      Abstract will be available on 2073-06-01
    • Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells 

      Aass, Kristin Roseth; Mjelle, Robin; Kastnes, Martin Haugrud; Tryggestad, Synne Stokke; van den Brink, Luca M; Roseth, Ingrid Aass; Westhrin, Marita; Zahoor, Muhammad; Moen, Siv Helen; Nedal, Tonje Marie Vikene; Buene, Glenn; Misund, Kristine; Sponaas, Anne-Marit; Ma, Qianli; Sundan, Anders; Groen, Richard WJ; Slørdahl, Tobias Schmidt; Waage, Anders; Standal, Therese (Journal article; Peer reviewed, 2021)
      Interleukin-32 (IL-32) is a nonclassical cytokine expressed in cancers, inflammatory diseases, and infections. Its expression is regulated by two different oxygen sensing systems; HIF1α and cysteamine dioxygenase (ADO), ...
    • Modification of glycosyltransferases in multiple myeloma 

      Johansen, Victoria (Master thesis, 2021)
      Myelomatose, også kjent som beinmargskreft, er en kreftsykdom som kjennetegnes av ukontrollert vekst av plasmaceller i beinmargen. Nesten alle myelomatosepasienter utvikler en beinsykdom som følge av kreftsykdommen, og ...
    • Multiple Myeloma: Cancer Cell Intrinsic- and Tumor Microenvironmental Factors 

      Nedal, Tonje Marie Vikene (Doctoral theses at NTNU;2024:33, Doctoral thesis, 2024)
      Myelomatose (MM) er en hematologisk kreftsykdom som skyldes ukontrollert vekst av maligne plasmaceller i beinmargen. Myelomatose utvikler seg via to asymptomatiske forstadier: monoklonal gammopati av usikker betydning ...
    • Paired miRNA- and messenger RNA-sequencing identifies novel miRNA-mRNA interactions in multiple myeloma 

      Aass, Kristin Roseth; Nedal, Tonje Marie Vikene; Tryggestad, Synne Stokke; Haukås, Einar; Slørdahl, Tobias Schmidt; Waage, Anders; Standal, Therese; Mjelle, Robin (Peer reviewed; Journal article, 2022)
      Multiple myeloma (MM) is an incurable cancer of terminally differentiated plasma cells that proliferate in the bone marrow. miRNAs are promising biomarkers for risk stratification in MM and several miRNAs are shown to have ...