Blar i NTNU Open på forfatter "Martín-Alonso, Mara"

Viser treff 1-3 av 3

    • E-cadherin cleavage by MT2-MMP regulates apical junctional signaling and epithelial homeostasis in the intestine 

      Gómez-Escudero, Jesús; Moreno, Vanessa; Martín-Alonso, Mara; Hernández de Riquer, M. Victoria; Feinberg, Tamar; Colmenar, Ángel; Calvo, Enrique; Camafeita, Emilio; Martínez, Fernando; J. Weiss, Stephen; Arroyo, Alicia G.; J. Oudhoff, Menno (Journal article; Peer reviewed, 2017)
      Cadherin-based intercellular adhesions are essential players in epithelial homeostasis, but their dynamic regulation during tissue morphogenesis and remodeling remain largely undefined. Herein, we characterize an unexpected ...

    • Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection 

      Parmar, Naveen; Burrows, Kyle; Vornewald, Pia M.; Lindholm, Håvard T.; Zwiggelaar, Rosalie T.; Díez-Sánchez, Alberto; Martín-Alonso, Mara; Fosslie, Madeleine; Vallance, Bruce A.; Dahl, John Arne; Zaph, Colby; Oudhoff, Menno J. (Peer reviewed; Journal article, 2021)
      Infectious and inflammatory diseases in the intestine remain a serious threat for patients world-wide. Reprogramming of the intestinal epithelium towards a protective effector state is important to manage inflammation and ...

    • LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium 

      Zwiggelaar, Rosalie; Lindholm, Håvard Takle; Fosslie, Madeleine Lystad; Pedersen, Marianne Terndrup; Ohta, Yuki; Díez-Sánchez, Alberto; Martín-Alonso, Mara; Ostrop, Jenny; Matono, Mami; Parmar, Naveen; Kvaløy, Emilie; Spanjers, Roos; Nazmi, Kamran; Rye, Morten Beck; Drabløs, Finn; Arrowsmith, Cheryl H; Dahl, John Arne; Jensen, Kim B.; Sato, Toshiro; Oudhoff, Menno (Journal article; Peer reviewed, 2020)
      Intestinal epithelial homeostasis is maintained by adult intestinal stem cells, which, alongside Paneth cells, appear after birth in the neonatal period. We aimed to identify regulators of neonatal intestinal epithelial ...