Browsing NTNU Open by Author "Loevenich, Simon"
Now showing items 1-6 of 6
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Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection
Loevenich, Simon; Malmo, Jostein; Liberg, Ann Magritt; Sherstova, Tatyana; Li, Youxian; Rian, Kristin; Johnsen, Ingvild Bjellmo; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2019)Human metapneumovirus (HMPV) may cause severe respiratory disease. The early innate immune response to viruses like HMPV is characterized by induction of antiviral interferons (IFNs) and proinflammatory immune mediators ... -
Characterization of signaling pathways regulating the expression of pro-inflammatory long form thymic stromal lymphopoietin upon human metapneumovirus infection
Li, Youxian; Lund, Cecilie; Nervik, Ida; Loevenich, Simon; Døllner, Henrik; Anthonsen, Marit Walbye; Johnsen, Ingvild Bjellmo (Journal article; Peer reviewed, 2018)Thymic stromal lymphopoietin (TSLP) is associated with several allergic diseases including asthma. Two isoforms of TSLP exist in humans, a long form (lfTSLP) and a short form (sfTSLP), displaying distinct immunological ... -
Cytokine profiles in human metapneumovirus infected children: Identification of genes involved in the antiviral response and pathogenesis
Malmo, Jostein; Moe, Nina; Krokstad, Sidsel; Ryan, Liv; Loevenich, Simon; Johnsen, Ingvild Bjellmo; Espevik, Terje; Nordbø, Svein Arne; Døllner, Henrik; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2016)Human metapneumovirus (hMPV) causes severe airway infection in children that may be caused by an unfavorable immune response. The nature of the innate immune response to hMPV in naturally occurring infections in children ... -
Human metapneumovirus driven IFN-β production antagonizes macrophage transcriptional induction of IL1-β in response to bacterial pathogens
Loevenich, Simon; Montaldo, Nicola Pietro; Wickenhagen, Arthur; Sherstova, Tatyana; van Loon, Barbara; Boyartchuk, Victor; Anthonsen, Marit Walbye (Journal article; Peer reviewed, 2023) -
Human Metapneumovirus Induces IRF1 via TANK-Binding Kinase 1 and Type I IFN
Loevenich, Simon; Spahn, Alix Saskia; Rian, Kristin; Boyartchuk, Victor; Anthonsen, Marit Walbye (Peer reviewed; Journal article, 2021)The innate immune and host-protective responses to viruses, such as the airway pathogen human metapneumovirus (HMPV), depend on interferons (IFNs) that is induced through TANK-binding kinase 1 (TBK1) and IFN regulatory ... -
Innate immune responses to human metapneumovirus - Exploring cellular models and molecular mechanisms of interferon regulation and action
Loevenich, Simon (Doctoral theses at NTNU;2020:101, Doctoral thesis, 2020)Luftveisinfeksjoner forårsaket av virus og bakterier er et betydelig folkehelseproblem. Særlig for barn, gamle mennesker og personer med lungesykdom eller svekket immunsystem kan disse infeksjonene være livstruende. For ...