Browsing NTNU Open by Author "Jin, Yang"
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A systemic study of lipid metabolism regulation in salmon fingerlings and early juveniles fed plant oil
Jin, Yang; Olsen, Rolf Erik; Gillard, Gareth B.; Østensen, Mari-Ann; Korsvoll, Sven A.; Santi, Nina; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)In salmon farming, the scarcity of fish oil has driven a shift towards the use of plant-based oil from vegetable or seed, leading to fish feed low in long-chain PUFA (LC-PUFA) and cholesterol. Atlantic salmon has the ... -
Atlantic salmon raised with diets low in long-chain polyunsaturated n-3 fatty acids in freshwater have a Mycoplasma-dominated gut microbiota at sea
Jin, Yang; Angell, Inga Leena; Sandve, Simen Rød; Snipen, Lars-Gustav; Olsen, Yngvar; Rudi, Knut (Journal article; Peer reviewed, 2019)Factors affecting the establishment of the gut microbiota in animals living in marine environments remain largely unknown. In terrestrial animals, however, it is well established that the juvenile environment has a major ... -
Comparative transcriptomics reveals domestication‐associated features of Atlantic salmon lipid metabolism
Jin, Yang; Olsen, Rolf Erik; Harvey, Thomas Nelson; Østensen, Mari-Ann; Li, Keshuai; Santi, Nina; Vadstein, Olav; Bones, Atle M.; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Peer reviewed; Journal article, 2020)Domestication of animals imposes strong targeted selection for desired traits but can also result in unintended selection due to new domestic environments. Atlantic salmon was domesticated in the 1970s and has subsequently ... -
CRISPR/Cas9-mediated ablation of elovl2 in Atlantic salmon (Salmo salar L.) inhibits elongation of polyunsaturated fatty acids and induces Srebp-1 and target genes
Winge, Per; Datsomor, Alex; Olsen, Rolf Erik; Jin, Yang; Vik, Jon Olav; Edvardsen, Rolf; Grammes, Fabian; Wargelius, Anna; Li, Keshuai (Journal article; Peer reviewed, 2019)Atlantic salmon can synthesize polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (20:5n-3), arachidonic acid (20:4n-6) and docosahexaenoic acid (22:6n-3) via activities of very long chain fatty acyl elongases ... -
Development of lipid metabolism in early life stages of Atlantic salmon (Salmo salar)
Jin, Yang (Doctoral theses at NTNU;2019:47, Doctoral thesis, 2019)Development of lipid metabolism in early life stages of Atlantic salmon (Salmo salar) Larval and juvenile stages are critical periods for Atlantic salmon (Salmo salar), which can have a major impact on growth and ... -
Diet and Life Stage-Associated Lipidome Remodeling in Atlantic Salmon
Jin, Yang; Harvey, Thomas Nelson; Bartosova, Zdenka; Hassani, Sahar; Bruheim, Per; Sandve, Simen Rød; Vik, Jon Olav (Peer reviewed; Journal article, 2021)Salmon is an important source of long-chain highly unsaturated fatty acids (LC-HUFAs) such as 22:6n-3 [docosahexaenoic acid (DHA)]. In the present study, we conducted two identical experiments on salmon in freshwater (FW) ... -
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry
Jalili, Mahsa; Jin, Yang; Bones, Atle M.; Olsen, Yngvar; Vadstein, Olav; Østensen, Mari-Ann; Buonocore, Francesco; Gerdol, Marco; Pallavicini, Alberto; Scapigliati, Giuseppe (Journal article; Peer reviewed, 2019)The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during early life ... -
Life-stage associated remodeling of lipid metabolism regulation in Atlantic salmon
Gillard, Gareth Benjamin; Harvey, Thomas Nelson; Gjuvsland, Arne Bjørke; Jin, Yang; Thomassen, Magny Sissel S.; Lien, Sigbjørn; Leaver, Michael; Torgersen, Jacob Seilø; Hvidsten, Torgeir Rhoden; Vik, Jon Olav; Sandve, Simen Rød (Journal article; Peer reviewed, 2018)Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before returning to spawn in freshwater. The transition to marine habitats is associated with dramatic changes in the environment, including water ... -
Molecular Regulation of Biosynthesis of Long Chain Polyunsaturated Fatty Acids in Atlantic Salmon
Datsomor, Alex Kojo; Gillard, Gareth Benjamin; Jin, Yang; Olsen, Rolf Erik; Sandve, Simen Rød (Peer reviewed; Journal article, 2022)Salmon is a rich source of health-promoting omega-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), such as eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). The LC-PUFA biosynthetic pathway ... -
Targeted mutagenesis of Δ5 and Δ6 fatty acyl desaturases induce dysregulation of lipid metabolism in Atlantic salmon (Salmo salar)
Jin, Yang; Datsomor, Alex Kojo; Olsen, Rolf Erik; Vik, Jon Olav; Torgersen, Jacob Seilø; Edvardsen, Rolf Brudvik; Wargelius, Anna; Winge, Per; Grammes, Fabian (Peer reviewed; Journal article, 2020)Background With declining wild fish populations, farmed salmon has gained popularity as a source for healthy long-chain highly unsaturated fatty acids (LC-HUFA). However, the introduction of plant oil in farmed salmon ... -
Time kinetics of fatty acids changes in total lipids and phospholipids of A. franciscana following enrichment and starvation, with a main focus on docosahexaenoic acid (DHA)
Jin, Yang (Master thesis, 2013)HUFA in PL has been considered to be easily digested by marine fish larvae, which will result in better growth, survival and development (e.g., pigmentation, stress resistance and gut maturation). As one of the most commonly ... -
Transcriptional development of phospholipid and lipoprotein metabolism in different intestinal regions of Atlantic salmon (Salmo salar) fry
Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Korsvoll, Sven Arild; Santi, Nina; Gjuvsland, Arne Bjørke; Vik, Jon Olav; Torgersen, Jacob Seilø; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)Background It has been suggested that the high phospholipid (PL) requirement in Atlantic salmon (Salmo salar) fry is due to insufficient intestinal de-novo synthesis causing low lipoprotein (LP) production and reduced ... -
Transcriptional regulation of lipid metabolism when salmon fry switches from endogenous to exogenous feeding
Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Li, Keshuai; Harvey, Thomas Nelson; Santi, Nina; Vadstein, Olav; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)The onset of first feeding is a critical period for Atlantic salmon (Salmo salar). The fish goes through a dramatic transition, from using the yolk sac as an energy and nutrient resource to rely on exogenous food. However, ...