Browsing NTNU Open by Author "Hestad, Knut"
Now showing items 1-20 of 23
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Adult neuropsychological testing in Zambia’s HIV positive population on combined antiretroviral therapy
Kabuba, Norma (Doctoral theses at NTNU;2018:232, Doctoral thesis, 2018)The effect of human immunodeficiency virus (HIV) on the central nervous system results in a number of cognitive problems. Although the introduction of combined antiretroviral therapy (CART) has resulted in the reduction ... -
APOE – a genetic marker of comorbidity in subjects with morbid obesity
Farup, Per Grønaas; Rootwelt, Helge; Hestad, Knut (Peer reviewed; Journal article, 2020)Background In population-based studies, the genetic variability of the APOE E alleles have been associated with health outcomes. Health problems are common in subjects with obesity. This study explored associations ... -
Betydelsen av depressiva och schizofrena symptom i neuropsykologiska utredningar
Stenberg, Jonas (Master thesis, 2010)Ett av huvudsyftena vid en neuropsykologisk undersökning är att bestämma huruvida en patients resultat tyder på hjärnskada eller inte. Forskning på psykiatriska patienter har visat att psykopatologi som schizofreni, och i ... -
Betydelsen av depressiva och schizofrena symptom i neuropsykologiska utredningar
Stenberg, Jonas (Master thesis, 2010)Ett av huvudsyftena vid en neuropsykologisk undersökning är att bestämma huruvida en patients resultat tyder på hjärnskada eller inte. Forskning på psykiatriska patienter har visat att psykopatologi som schizofreni, och i ... -
Cognitive Functions and Depression in Patients with Irritable Bowel Syndrome
Farup, Per Grønaas; Hestad, Knut (Journal article; Peer reviewed, 2015)Background. Irritable bowel syndrome (IBS) is associated with depression and depression with impaired cognitive functions. The primary aim was to study associations between depression and cognitive functions in patients ... -
Depression has a strong relationship to alterations in the immune, endocrine ad neural system
Hestad, Knut; Aukrust, P.; Tønseth, S; Reitan, Solveig Klæbo (Journal article; Peer reviewed, 2009)Epidemiological findings indicate a connection between depressive symptoms and changes in status of the immune system in depressed patients. This raises the possibility of causative connections. Theories on mechanisms for ... -
Effect of Age and Level of Education on Neurocognitive Impairment in HIV Positive Zambian Adults
Kabuba, Norma Namasiku Zewelanji; Menon, Anitha; Franklin, Donald R.; Lydersen, Stian; Heaton, Robert K.; Hestad, Knut (Journal article; Peer reviewed, 2018)Objective: Older age and lower education levels are known to be associated with worse neurocognitive (NC) performance in healthy adults, and individuals with HIV infection may experience accelerated brain/cognition aging. ... -
Faecal short-chain fatty acids - a diagnostic biomarker for irritable bowel syndrome?
Farup, Per Grønaas; Rudi, Knut; Hestad, Knut (Journal article; Peer reviewed, 2016)Background The diagnosis of irritable bowel syndrome (IBS) relies on symptom-based criteria. A valid and reliable biomarker that could confirm the diagnosis is desirable. This study evaluated the properties of faecal ... -
Functional Bowel Disorders Are Associated with a Central Immune Activation
Farup, Per Grønaas; Ueland, Thor; Rudi, Knut; Lydersen, Stian; Hestad, Knut (Journal article; Peer reviewed, 2017)Background. Subjects with depression and unexplained neurological symptoms have a high prevalence of gastrointestinal comorbidity probably related to the brain-gut communication. This study explored associations between ... -
High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders
Neupane, Sudan Prasad; Lien, Lars; Martinez, Priscilla; Aukrust, Pål; Ueland, Thor; Mollnes, Tom Eirik; Hestad, Knut; Bramness, Jørgen Gustav (Journal article; Peer reviewed, 2014)As major depression (MD) is often comorbid with alcohol-use disorders (AUD) and alcohol itself modulates the immune system, we examined serum levels of interleukin (IL)-6, IL-10, tumor necrosis factor (TNF), and interferon ... -
HIV- and AIDS-associated neurocognitive functioning in Zambia - a perspective based on differences between the genders
Kabuba, Norma Namasiku Zewelanji; Menon, J. A.; Franklin, D.R. jr.; Heaton, R. K.; Hestad, Knut (Journal article; Peer reviewed, 2016)Human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) are frequently associated with neurocognitive impairment (NCI). However, few studies have examined the interrelationship between ... -
Increased frontal electroencephalogram theta amplitude in patients with anorexia nervosa compared to healthy controls
Hestad, Knut; Weider, Siri; Nilsen, Kristian Bernhard; Indredavik, Marit Sæbø; Sand, Trond (Journal article; Peer reviewed, 2016)Objective: To conduct a blind study of quantitative electroencephalogram-band amplitudes in patients with anorexia nervosa (AN) and healthy controls. Methods: Twenty-one patients with AN and 24 controls were examined with ... -
Neurocognitive Outcome and Compensating Possibilities in Children and Adolescents Treated for Acute Lymphoblastic Leukemia With Chemotherapy Only
Lofstad, Grete Elisabeth; Reinfjell, Trude; Weider, Siri; Diseth, Trond H; Hestad, Knut (Journal article; Peer reviewed, 2019)Aim: To examine the neurocognitive outcomes in children and adolescents with acute lymphoblastic leukemia (ALL) in remission who were treated with systemic chemotherapy only (CTO). Methods: Neurocognitive performances ... -
Neuropsychological function in individuals with morbid obesity: A cross-sectional study
Sargénius, Hanna; Lydersen, Stian; Hestad, Knut (Journal article; Peer reviewed, 2017)Background:Previous research has shown cognitive dysfunction to be present in a significant number ofindividuals with obesity. The objective of this study was to assess the neuropsychological profile of morbidlyobese ... -
Neuropsychological manifestations in morbid obesity
Sargénius, Hanna Lovise (Doctoral theses at NTNU;2018:106, Doctoral thesis, 2018)Norsk samandrag: Framleis veit vi ikkje heilt sikkert kva som er dei eksakte underliggjande mekanismane til fedme. Eit spørsmål som stadig vert diskutert er kvifor nokre av oss har større vanskar med å halde ei sunn ... -
Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis
Hestad, Knut; Engedal, Knut; Aukrust, Pål; Farup, Per Grønaas; Mollnes, Tom Eirik; Ueland, Thor (Journal article; Peer reviewed, 2016-04-13)Introduction: Several reports indicate that inflammation may play a role in depression and demonstrate enhanced systemic levels of inflammatory mediators. We hypothesized that 44 patients with a diagnosis of depression ... -
Predicting acute side effects of stimulant medication in pediatric attention deficit/hyperactivity disorder: data from quantitative electroencephalography, event-related potentials, and a continuous-performance test
Øgrim, Kjell Geir; Hestad, Knut; Brunner, Jan; Kropotov, Yury (Journal article; Peer reviewed, 2013)Background: The aim of this study was to search for predictors of acute side effects of stimulant medication in pediatric attention deficit/hyperactivity disorder (ADHD), emphasizing variables from quantitative ... -
Predicting the clinical outcome of stimulant medication in pediatric attention-deficit/hyperactivity disorder: data from quantitative electroencephalography, event-related potentials, and a go/no-go test
Øgrim, Kjell Geir; Kropotov, Yury; Brunner, Jan; Candrian, Gian; Sandvik, Leiv; Hestad, Knut (Journal article; Peer reviewed, 2014)Background: We searched for predictors of the clinical outcome of stimulant medication in pediatric attention-deficit/hyperactivity disorder (ADHD), emphasizing variables from quantitative electroencephalography, event-related ... -
PTSD patients show increasing cytokine levels during treatment despite reduced psychological distress.
Toft, Helge Prytz; Bramness, Jørgen Gustav; Lien, Lars; Abebe, Dawit Shawel; Wampold, Bruce E.; Tilden, Terje; Hestad, Knut; Neupane, Sudan Prasad (Journal article; Peer reviewed, 2018)Background: A reciprocal relationship between activated innate immune system and changes in mood and behavior has been established. There is still a paucity of knowledge on how the immune system responds during psychiatric ... -
The effect of ApoE e4 on blood pressure in patients with and without depression
Hestad, Knut; Engedal, Knut; Whist, Jon Elling; Farup, Per Grønaas (Journal article; Peer reviewed, 2016)Introduction: Depression is considered an independent risk factor for hypertension, particularly for people with recurrent episodes or a long history of depression. Another risk factor for cardiovascular disease is the ...