• Best practice guidelines for blunt cerebrovascular injury (BCVI) 

      Brommeland, Tor; Helseth, Eirik; Aarhus, Mads; Moen, Kent Gøran; Dyrskog, Stig; Bergholt, Bo; Olivecrona, Zandra; Jeppesen, Elisabeth (Journal article; Peer reviewed, 2018)
      Blunt cerebrovascular injury (BCVI) is a non-penetrating injury to the carotid and/or vertebral artery that may cause stroke in trauma patients. Historically BCVI has been considered rare but more recent publications ...
    • Best practice guidelines for blunt cerebrovascular injury (BCVI) : 

      Brommeland, Tor; Helseth, Eirik; Aarhus, Mads; Moen, Kent Gøran; Dyrskog, Stig; Bergholt, Bo; Olivecrona, Zandra; Jeppesen, Elisabeth (Journal article; Peer reviewed, 2018)
      Blunt cerebrovascular injury (BCVI) is a non-penetrating injury to the carotid and/or vertebral artery that may cause stroke in trauma patients. Historically BCVI has been considered rare but more recent publications ...
    • Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study 

      Czeiter, Endre; Amrein, Krisztina; Gravesteijn, BY; Lecky, Fiona; Menon, David K; Mondello, Stefania; Newcombe, Virginia F; Richter, Sophie; Steyerberg, Ewout W; Vande Vyvere, Thijs; Verheyden, Jan; Xu, Haiyan; Yang, Zhihui; Maas, Andrew I.R.; Wang, Kevin KW; Buki, Andras; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa (Peer reviewed; Journal article, 2020)
      Background: Serum biomarkers may inform and improve care in traumatic brain injury (TBI). We aimed to correlate serum biomarkers with clinical severity, care path and imaging abnormalities in TBI, and explore their incremental ...
    • Brain death and postmortem organ donation: report of a questionnaire from the CENTER-TBI study 

      van Veen, Ernest; Van Der Jagt, Mathieu; Cnossen, Maryse C.; Maas, Andrew I. R.; De Beaufort, Inez D.; Menon, David K.; Citerio, Giuseppe; Stocchetti, Nino; Rietdijk, Wim J. R.; van Dijck, Jeroen T. J. M.; Kompanje, Erwin J. O.; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Peer reviewed, 2018)
      Background We aimed to investigate the extent of the agreement on practices around brain death and postmortem organ donation. Methods Investigators from 67 Collaborative European NeuroTrauma Effectiveness Research in ...
    • Changing care pathways and between-center practice variations in intensive care for traumatic brain injury across Europe: a CENTER-TBI analysis 

      Huijbers, Jilske; Wiegers, E; Lingsma, Hester F; Citerio, Giuseppe; Maas, Andrew I.R.; Menon, David K; Ercole, Ari; Nelson, David; van der Jagt, Mathieu; Steyerberg, Ewout; Helbok, Raimund; Lecky, Fiona; Peul, Wilco; Birg, Tatiana; Zoerle, Tomaso; Carbonara, Marco; Stocchetti, Nino; Andelic, Nada; Andreassen, Lasse; Lund, Stine Borgen; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Sandrød, Oddrun; Schirmer-Mikalsen, Kari; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Brorsson, Camilla; Azzolini, Maria Luisa; Bartels, Ronald; Beer, Ronny; Bellander, Bo-Michael; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Beqiri, Erta; Blaabjerg, Morten; Buki, Andras; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emaliana; Calvi, Maria Rosa; Cameron, Peter; Guillermo, Carbayo Lozano; Sundström, Nina; Tibboel, Dick; Ples, Horia; Sakowitz, Oliver; Ziverte, Agate (Peer reviewed; Journal article, 2020)
      Purpose: To describe ICU stay, selected management aspects, and outcome of Intensive Care Unit (ICU) patients with traumatic brain injury (TBI) in Europe, and to quantify variation across centers. Methods: This is a ...
    • Cognitive event-related potentials during the sub-acute phase of severe traumatic brain injury and their relationship to outcome 

      Hauger, Solveig Lægreid; Olafsen, Kjell; Schnakers, Caroline; Andelic, Nada; Nilsen, Kristian Bernhard; Helseth, Eirik; Funderud, Ingrid; Andersson, Stein; Schanke, Anne-Kristine; Løvstad, Marianne (Journal article; Peer reviewed, 2017)
      Predicting outcome in the early phase after severe traumatic brain injury (sTBI) is a major clinical challenge, particularly identifying patients with potential for good cognitive outcome.The current single-center prospective ...
    • Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury 

      Mikolic, Ana; van Klaveren, David; Oude Groeniger, Joost; Wiegers, E; Lingsma, Hester F; Zeldovich, Marina; von Steinbüchel, Nicole; Maas, Andrew I.R.; Roeters van Lennep, Jeanine; Polinder, Suzanne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina (Peer reviewed; Journal article, 2020)
      Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, ...
    • End-of-life practices in traumatic brain injury patients: Report of a questionnaire from the CENTER-TBI study 

      van Veen, Ernest; van der Jagt, Mathieu; Citerio, Guiseppe; Stocchetti, Nino; Epker, Jelle; Gommers, Diederik; Burdorf, Lex; Menon, David K; Maas, Andrew I.R.; Lingsma, Hester F; Kompanje, Erwin J.O.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)
      Purpose We aimed to study variation regarding specific end-of-life (EoL) practices in the intensive care unit (ICU) in traumatic brain injury (TBI) patients. Materials and methods Respondents from 67 hospitals ...
    • Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study 

      Andelic, Nada; Røe, Cecilie; Brunborg, Cathrine; Zeldovich, Marina; Løvstad, Marianne; Løke, Daniel; Borgen, Ida Maria Henriksen; Voormolen, Daphne; Howe, Emilie; Forslund, Marit Vindal; DAHL, HILDE MARGRETE; von Steinbuechel, Nicole; Helseth, Eirik; Røise, Olav; Frisvold, Shirin; Anke, Audny; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background Fatigue is one of the most commonly reported subjective symptoms following traumatic brain injury (TBI). The aims were to assess frequency of fatigue over the first 6 months after TBI, and examine whether fatigue ...
    • Global Characterisation of Coagulopathy in Isolated Traumatic Brain Injury (iTBI): A CENTER-TBI Analysis 

      Böhm, JK; Güting, Helge; Thorn, S; Schäfer, Nadine; Rambach, V; Schöchl, Herbert; Grottke, Oliver; Rossaint, Rolf; Stanworth, Simon; Curry, Nicola; Lefering, Rolf; Maegele, Marc; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background Trauma-induced coagulopathy in patients with traumatic brain injury (TBI) is associated with high rates of complications, unfavourable outcomes and mortality. The mechanism of the development of TBI-associated ...
    • Health-related quality of life after traumatic brain injury: deriving value sets for the QOLIBRI-OS for Italy, The Netherlands and The United Kingdom 

      Voormolen, Daphne; Polinder, Suzanne; von Steinbuechel, Nicole; Feng, Yan; Wilson, Lindsay; Oppe, Mark; Haagsma, Juanita; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Skandsen, Toril; Røe, Cecilie; Røise, Olav; Vik, Anne; Åkerlund, Cecilia; Adams, Hadie; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter;  Lozano, Guillermo Carbayo; Carbonara, Marco; Castaño-León, Ana M.; Chevallard, Giorgio; Chieregato, Arturo; Citerio, Giuseppe (Journal article; Peer reviewed, 2020)
      Purpose The Quality of Life after Brain Injury overall scale (QOLIBRI-OS) measures health-related quality of life (HRQoL) after traumatic brain injury (TBI). The aim of this study was to derive value sets for the QOLIBRI-OS ...
    • How do 66 European institutional review boards approve one protocol for an international prospective observational study on traumatic brain injury? Experiences from the CENTER-TBI study 

      Timmers, Marjolein; van Dijck, Jeroen T. J. M.; van Wijk, Roel P J; Legrand, Valerie; van Veen, Ernest; Maas, Andrew I.R.; Menon, David K; Citerio, Giuseppe; Stocchetti, Nino; Kompanje, Erwin J.O.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Cavallo, Simona (Peer reviewed; Journal article, 2020)
      Bakgrunn Den europeiske unionen (EU) har som mål å optimalisere pasientbeskyttelse og effektivitet i helseforskningen ved å harmonisere prosedyrer i alle medlemsstater. Likevel kreves ytterligere forbedringer for å øke ...
    • Machine learning algorithms performed no better than regression models for prognostication in traumatic brain injury 

      Gravesteijn, BY; Nieboer, Daan; Ercole, Ari; Lingsma, Hester F; Nelson, David; Van Calster, Ben; Steyerberg, Ewout W; Andelic, Nada; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne (Peer reviewed; Journal article, 2020)
      Objective We aimed to explore the added value of common machine learning (ML) algorithms for prediction of outcome for moderate and severe traumatic brain injury. Study Design and Setting We performed logistic regression ...
    • Post-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Study 

      Voomolen, DC; Haagsma, JA; Polinder, Suzanne; Maas, AIR; Steyerberg, Ewout W; Vulekovic, Peter; Sewalt, CA; Gravesteijn, BY; Covic, Amra; Andelic, Nada; Plass, AM; von Steinbüchel, Nicole; Vik, Anne; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin Kordasti; Helseth, Eirik; Skandsen, Toril; Røise, Olav; Håberg, Asta; Røe, Cecilie (Journal article; Peer reviewed, 2019)
      Abstract The aim of this study was to assess the occurrence of post-concussion symptoms and post-concussion syndrome (PCS) in a large cohort of patients after complicated and uncomplicated mild traumatic brain injury (mTBI) ...
    • Prediction of Global Functional Outcome and Post-Concussive Symptoms after Mild Traumatic Brain Injury: External Validation of Prognostic Models in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study 

      Mikolic, Ana; Polinder, Suzanne; Steyerberg, Ewout W; Retel Helmrich, Isabel; Giacino, Joseph T.; Maas, Andrew I.R.; van der Naalt, Joukje; Voormolen, Daphne; von Steinbüchel, Nicole; Wilson, Lindsay; Lingsma, Hester F; van Klaveren, David; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco (Peer reviewed; Journal article, 2020)
      The majority of traumatic brain injuries (TBIs) are categorized as mild, according to a baseline Glasgow Coma Scale (GCS) score of 13–15. Prognostic models that were developed to predict functional outcome and persistent ...
    • Prehospital Management of Traumatic Brain Injury across Europe: A CENTER-TBI Study 

      Gravesteijn, BY; Sewalt, Charlie; Stocchetti, Nino; Citerio, Giuseppe; Ercole, Ari; Lingsma, Hester F; Von Steinbuchel, Nicole; Steyerberg, Ewout W; Wilson, Lindsay; Maas, Andrew I.R.; Menon, David K; Lecky, Fiona E.; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Skandsen, Toril; Vik, Anne; Åkerlund, Cecilia; Amrein, Krisztina; Antoni, Anna; Audibert, Gerard; Azouvi, Philippe; Azzolini, Maria Luisa; Bartels, Ronald; Barzo, Pal; Beauvais, Romuald; Beer, Ronny; Bellander, Bo-Michael; Belli, Antonio; Benali, Habib; Berardino, Maurizio; Beretta, Luigi; Blaabjerg, Morten; Bragge, Peter; Brazinova, Alexandra; Brinck, Vibeke; Brooker, Joanne; Brorsson, Camilla; Buki, Andras; Bullinger, Monika; Cabeleira, Manuel; Caccioppola, Alessio; Calappi, Emiliana; Calvi, Maria Rosa; Cameron, Peter; Lozano, Guillermo Carbayo; Carbonara, Marco; Cavallo, Simona; Chevallard, Giorgio; Chieregato, Arturo (Peer reviewed; Journal article, 2020)
      Background: Prehospital care for traumatic brain injury (TBI) is important to prevent secondary brain injury. We aim to compare prehospital care systems within Europe and investigate the association of system characteristics ...
    • Quality indicators for patients with traumatic brain injury in European intensive care units: a CENTER-TBI study 

      Huijben, Jilske A.; Wiegers, E; Ercole, Ari; de Keizer, Nicolette; Maas, Andrew I. R.; Steyerberg, Ewout W.; Citerio, Giuseppe; Wilson, Lindsay; Polinder, Suzanne; Nieboer, Daan; Menon, David; Lingsma, Hester F.; Van Der Jagt, Mathieu; Andelic, Nada; Lund, Stine Borgen; Frisvold, Shirin; Helseth, Eirik; Røe, Cecilie; Røise, Olav; Schirmer-Mikalsen, Kari; Vik, Anne (Peer reviewed; Journal article, 2020)
      Background The aim of this study is to validate a previously published consensus-based quality indicator set for the management of patients with traumatic brain injury (TBI) at intensive care units (ICUs) in Europe and ...
    • Time of Injury and Relation to Alcohol Intoxication in Moderate-to-Severe Traumatic Brain Injury: A Decade-Long Prospective Study 

      Bjarkø, Vera Vik; Skandsen, Toril; Moen, Kent Gøran; Gulati, Sasha; Helseth, Eirik; Nilsen, Tom Ivar Lund; Vik, Anne (Journal article; Peer reviewed, 2018)
      Background Knowledge about the causes and time of injury for traumatic brain injury (TBI) is important for the development of efficient prevention policies. We aimed to study time of injury and relation to alcohol ...
    • Variation in general supportive and preventive intensive care management of traumatic brain injury: a survey in 66 neurotrauma centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study 

      Huijben, Jilske A.; Volovici, Victor; Cnossen, Maryse C.; Haitsma, Iain K.; Stocchetti, Nino; Maas, Andrew I. R.; Menon, David K.; Ercole, Ari; Citerio, Giuseppe; Nelson, David; Polinder, Suzanne; Steyerberg, Ewout W.; Lingsma, Hester F.; van der Jagt, Mathieu; Vik, Anne; Andelic, Nada; Andreassen, Lasse; Anke, Audny; Frisvold, Shirin; Helseth, Eirik; Roise, Olav; Skandsen, Toril; Håberg, Asta; Røe, Cecilie (Journal article; Peer reviewed, 2018)
      Background General supportive and preventive measures in the intensive care management of traumatic brain injury (TBI) aim to prevent or limit secondary brain injury and optimize recovery. The aim of this survey was to ...
    • Variation in neurosurgical management of traumatic brain injury: a survey in 68 centers participating in the CENTER-TBI study. 

      Van Essen, Thomas; den Boogert, HF; Cnossen, MC; De Ruiter, Godard CW; Haitsma, Ian; Polinder, S; Steyerberg, Ewout W.; Menon, David; Maas, Andrew I. R.; Lingsma, Hester F; Peul, Wilco; Andelic, Nada; Helseth, Eirik; Roise, O; Røe, Cecilie; Vik, Anne; Skandsen, Toril; Anke, Audny; Frisvold, Shirin Kordasti; Andreassen, Lasse; Håberg, Asta (Journal article; Peer reviewed, 2018)
      Background Neurosurgical management of traumatic brain injury (TBI) is challenging, with only low-quality evidence. We aimed to explore differences in neurosurgical strategies for TBI across Europe. Methods A survey ...