Blar i NTNU Open på forfatter "Halaas, Øyvind"
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Actuation of a Hyperelastic PDMS Membrane Suspended inside a Microfluidic Channel: From Computer Simulation to Microfabrication
Ribe, Jonas Myren (Master thesis, 2012)This Master-project was done in the Department of Physics at NTNU in the spring of 2012. The project develops micro- and nanofabrication processes useful for lab-on-a-chip systems. These systems aim to scale down and ... -
Assessing cell migration in hydrogels: An overview of relevant materials and methods
Solbu, Anita Akbarzadeh; Caballero, David; Damigos, Spyridon; Kundu, Subhas; Reis, Rui L.; Halaas, Øyvind; Chahal, Aman Singh; Strand, Berit Løkensgard (Peer reviewed; Journal article, 2023)Cell migration is essential in numerous living processes, including embryonic development, wound healing, immune responses, and cancer metastasis. From individual cells to collectively migrating epithelial sheets, the ... -
Developing long-term in vitro microculture for neuropathology modelling
Ramstad, Ola Huse (Master thesis, 2016)Background: The regenerative capacity of the adult mammalian central nervous system is limited, while neuronal responses to injury, including axonal and synaptic plasticity are highly complex and evolve in a spatiotemporal ... -
Dynamics of immune effector mechanisms during infection with Mycobacterium aviumin C57BL/6 mice
Haug, Markus; Awuh, Jane Atesoh; Steigedal, Magnus; Kojen, June Frengen; Marstad, Anne; Nordrum, Ivar Skjåk; Halaas, Øyvind; Flo, Trude Helen (Journal article; Peer reviewed, 2013)Opportunistic infections with non-tuberculous mycobacteria such as Mycobacterium avium are receiving renewed attention because of increased incidence and difficulties in treatment. As for other mycobacterial infections, a ... -
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity
Husebye, Harald; Halaas, Øyvind; Stenmark, Harald; Tunheim, G; Sandanger, Øystein; Bogen, B; Brech, A; Latz, Eicke; Espevik, Terje (Journal article; Peer reviewed, 2006)Immune responses are initiated when molecules of microbial origin are sensed by the Toll‐like receptors (TLRs). We now report the identification of essential molecular components for the trafficking of the lipopolysaccharide ... -
IMMUNITY-ON-A-CHIP Microfluidic Devices for Immunoengineering
Moura Rosa, Patrícia (Doctoral theses at NTNU;2017:357, Doctoral thesis, 2017)Immunitet-på-mikrobrikke Mikrofluidiske innretninger for immunologisk forskning og utvikling Sammendrag: Det siste tiåret har mikrofluidteknologi, dvs væskestrømmer i mikroskala basert på prosesser fra halvlederindustrien, ... -
Integration of Alginate Hydrogels with Microfluidic Devices for use in Tissue-on-Chip Applications
Kyvik, Adriana Ruiz (Master thesis, 2015)The use of hydrogels in tissue engineering together with the emerging applications of tissue- on-chip technology is an expanding research field. Hydrogels have been widely used as cell scaffolds in order to replicate the ... -
Migration of T-cells in a multi-compartment hydrogel model of inflammation
Damigos, Spyridon (Master thesis, 2020)In the present work multi-compartmental hydrogels were established in order to study T-cell migration in 3D. The main approach that was developed for the fabrication of the hydrogel systems, was based on the incorporation ... -
Photochemical internalization of peptide antigens provides a novel strategy to realize therapeutic cancer vaccination
Haug, Markus; Brede, Gaute; Håkerud, Monika; Nedberg, Anne Grete; Gederaas, Odrun Arna; Flo, Trude Helen; Edwards, Victoria Tudor; Selbo, Pål Kristian; Høgset, Anders; Halaas, Øyvind (Journal article; Peer reviewed, 2018)Effective priming and activation of tumor-specific CD8+ cytotoxic T lymphocytes (CTLs) is crucial for realizing the potential of therapeutic cancer vaccination. This requires cytosolic antigens that feed into the MHC class ... -
Seeing a Mycobacterium-Infected Cell in Nanoscale 3D: Correlative Imaging by Light Microscopy and FIB/SEM Tomography
Beckwith, Marianne; Beckwith, Kai Sandvold; Sikorski, Pawel; Skogaker, Nan Elisabeth Tostrup; Flo, Trude Helen; Halaas, Øyvind (Journal article; Peer reviewed, 2015)Mycobacteria pose a threat to the world health today, with pathogenic and opportunistic bacteria causing tuberculosis and non-tuberculous disease in large parts of the population. Much is still unknown about the interplay ... -
Structuring a multi-nodal neural network in vitro within a novel design microfluidic chip
van de Wijdeven, Rosanne; Huse Ramstad, Ola; Bauer, Ulrich Stefan; Halaas, Øyvind; Sandvig, Axel; Sandvig, Ioanna (Journal article; Peer reviewed, 2018)Neural network formation is a complex process involving axon outgrowth and guidance. Axon guidance is facilitated by structural and molecular cues from the surrounding microenvironment. Micro-fabrication techniques can be ... -
Tailored microfluidic platforms for advanced neurobiology, neuroengineering and electrophysiology
van de Wijdeven, Rosanne (Doctoral theses at NTNU;2019:135, Doctoral thesis, 2019) -
Targeted correlative light and electron microscopy in the study of host-pathogen interactions
Beckwith, Marianne S (Doktoravhandlinger ved NTNU;2018:89, Doctoral thesis, 2018)Abstract Tuberculosis (TB) and HIV are the two deadliest infectious diseases in the world today. 1,8 million people died from TB in 2015, 400.000 of which were HIV positive. Drug resistant TB strains are rapidly spreading, ... -
The Establishment of a Co-culture to Generate Young Memory T Cells
Haabeth, Emma (Master thesis, 2023)Adoptiv celleterapi (ACT) er en lovende behandling mot flere typer kreft ved bruk av infusjon av tumor-spesifikke cytotoxiske T-celler. De infiltrerte T-lymfocyttene i ACT er typisk høyt differensierte, med kort ... -
Towards Making a Cyborg: A Closed-Loop Reservoir-Neuro System
Aaser, Peter; Knudsen, Martinius; Huse Ramstad, Ola; van de Wijdeven, Rosanne; Nichele, Stefano; Sandvig, Ioanna; Tufte, Gunnar; Bauer, Ulrich Stefan; Halaas, Øyvind; Hendseth, Sverre; Sandvig, Axel; Valderhaug, Vibeke Devold (Chapter; Peer reviewed, 2017)The human brain is a remarkable computing machine, i.e. vastly parallel, self-organizing, robust, and energy efficient. To gain a better understanding into how the brain works, a cyborg (cybernetic organism, a combination ...