Browsing NTNU Open by Author "Hagen, Knut"
Now showing items 1-20 of 74
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A 4-year follow-up of patients with medication-overuse headache previously included in a randomized multicentre study
Hagen, Knut; Albretsen, Claus; Vilming, Steinar; Salvesen, Rolf; Grønning, Marit; Helde, Grethe; Gravdahl, Gøril Bruvik; Zwart, John-Anker; Stovner, Lars Jacob (Journal article; Peer reviewed, 2011) -
A Comparison of Anthropometric Measures for Assessing the Association between Body Size and Risk of Chronic Low Back Pain: TheHUNT Study
HEUCH, INGRID; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Journal article, 2015)Background: Previous work indicates that overweight and obese individuals carry an increased risk of experiencing chronic low back pain (LBP). It is not known, however, how the association with body size depends on the ... -
Anxiety, depression and behavioral problems among adolescents with recurrent headache: the Young-HUNT study
Blaauw, Brit Andenes; Dyb, Grete; Hagen, Knut; Holmen, Turid Lingaas; Linde, Mattias; Wentzel-Larsen, Tore; Zwart, John-Anker (Journal article; Peer reviewed, 2014)Background It is well documented that both anxiety and depression are associated with headache, but there is limited knowledge regarding the relation between recurrent primary headaches and symptoms of anxiety and ... -
Association between blood pressure measures and recurrent headache in adolescents: cross-sectional data from the HUNT-Youth study
Tronvik, Erling; Zwart, John-Anker; Hagen, Knut; Dyb, Grete; Holmen, Turid Lingaas; Stovner, Lars Jacob (Journal article; Peer reviewed, 2011)The relationship between blood pressure and headache in youth has not been explored and the objective of the present study was to provide data on this association in an adolescent population. Cross-sectional data from a ... -
Association between body height and chronic low back pain: a follow-up in the Nord-Trøndelag Health Study.
HEUCH, INGRID; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Journal article; Peer reviewed, 2015)Objective To study potential associations between body height and subsequent occurrence of chronic low back pain (LBP). Design Prospective cohort study. Setting The North-Trøndelag Health Study (HUNT). Data ... -
Associations between the number of children, age at childbirths and prevalence of chronic low back pain: the Nord- Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Storheim, Kjersti; Zwart, John-Anker (Peer reviewed; Journal article, 2020)Background Associations between childbirths and subsequent risk of low back pain (LBP) have not been clarified. Changes in sex hormone levels or lumbar posture during pregnancy may have an impact on LBP later in life. ... -
The bidirectional temporal relationship between headache and affective disorders: longitudinal data from the HUNT studies
Giri, Samita; Tronvik, Erling Andreas; Hagen, Knut (Peer reviewed; Journal article, 2022)Background Few prospective population-based studies have evaluated the bidirectional relationship between headache and affective disorder. The aim of this large-scale population-based follow-up study was to investigate ... -
Caesarean section and the association with migraine: a retrospective register-linked HUNT population cohort study
Kristoffersen, Espen Saxhaug; Børte, Sigrid; Hagen, Knut; Zwart, John-Anker; Winsvold, Bendik K S (Peer reviewed; Journal article, 2020)Objectives To evaluate the association between caesarean section and migraine in a population-based register-linked cohort study. Setting Data from the population-based Nord-Trøndelag Health Studies (HUNT2 and HUNT3) ... -
Cerebral cortical dimensions in headache sufferers aged 50-66 years: a population-based imaging study in the Nord-Trondelag Health Study (HUNT-MRI)
Husøy, Andreas Kattem; Håberg, Asta Kristine; Rimol, Lars Morten; Hagen, Knut; Vangberg, Torgil Riise; Stovner, Lars Jacob (Journal article; Peer reviewed, 2019)Based on previous clinic-based magnetic resonance imaging studies showing regional differences in the cerebral cortex between those with and without headache, we hypothesized that headache sufferers have a decrease in ... -
Depression and anxiety in relation to catechol-O-methyltransferase Val158Met genotype in the general population: The Nord-Trøndelag Health Study (HUNT)
Bækken, Petter; Skorpen, Frank; Stordal, Eystein; Zwart, John-Anker; Hagen, Knut (Journal article; Peer reviewed, 2008)Background: The catechol-O-methyltransferase (COMT) gene contains a functional polymorphism, Val158Met, which has been linked to anxiety and depression, but previous results are not conclusive. The aim of the present ... -
Diffusion tensor imaging in middle-aged headache sufferers in the general population: A cross-sectional population-based imaging study in the Nord-Trøndelag health study (HUNT-MRI)
Husøy, Andreas Kattem; Eikenes, Live; Håberg, Asta; Hagen, Knut; Stovner, Lars Jacob (Journal article; Peer reviewed, 2019)Background Several studies have investigated white matter with diffusion tensor imaging (DTI) in those suffering from headache, but so far only in clinic based samples and with conflicting results. Methods In the present ... -
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Peer reviewed; Journal article, 2022)Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ... -
Do abnormal serum lipid levels increase the risk of chronic low back pain? The Nord-Trøndelag Health Study
HEUCH, INGRID; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Journal article; Peer reviewed, 2014)Background: Cross-sectional studies suggest associations between abnormal lipid levels and prevalence of low back pain (LBP), but it is not known if there is any causal relationship. Objective: The objective was to ... -
Do incident musculoskeletal complaints influence mortality? The Nord-Trøndelag Health study
Åsberg, Anders Nikolai; Hagen, Knut; Stovner, Lars Jacob; HEUCH, INGRID; Zwart, John-Anker; Winsvold, Bendik K S (Journal article; Peer reviewed, 2018)Background Musculoskeletal complaints (MSC) are common in the general population, causing a major disease burden to the individual and society. The association between MSC and mortality is still unclear. To our knowledge, ... -
Do physical activity and body mass index modify the association between chronic musculoskeletal pain and insomnia? Longitudinal data from the HUNT study, Norway.
Skarpsno, Eivind S.; Nilsen, Tom Ivar Lund; Sand, Trond; Hagen, Knut; Mork, Paul Jarle (Journal article; Peer reviewed, 2017)We investigated the prospective association between chronic musculoskeletal pain and risk of insomnia, and if leisure‐time physical activity and body mass index modify this association. The study comprised historical data ... -
Does diabetes influence the probability of experiencing chronic low back pain? A population-based cohort study: the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Sørgjerd, Elin Pettersen; Åsvold, Bjørn Olav; Zwart, John-Anker (Journal article; Peer reviewed, 2019)Objective Low back pain (LBP) is a major problem in modern society and it is important to study possible risk factors for this disorder. People with diabetes are often affected by LBP, but whether diabetes represents a ... -
Does health differ between participants and non-participants in the MRI-HUNT study, a population based neuroimaging study? The Nord-Trøndelag health studies 1984-2009
Honningsvåg, Lasse-Marius; Linde, Mattias; Håberg, Asta; Stovner, Lars Jacob; Hagen, Knut (Journal article; Peer reviewed, 2012)Background Bias with regard to participation in epidemiological studies can have a large impact on the generalizability of results. Our aim was to investigate the direction and magnitude of potential bias by comparing ... -
Does insomnia modify the association between C-reactive protein and migraine? The Tromsø Study 2015-2016.
Hagen, Knut; Hopstock, Laila Arnesdatter; Eggen, Anne Elise; Mathiesen, Ellisiv B.; Nilsen, Kristian Bernhard (Journal article; Peer reviewed, 2019)Background The relationship between high sensitivity C-reactive protein and migraine is unclear. The aim of this cross-sectional population-based study was to investigate the association between high sensitivity C-reactive ... -
Does pain sensitivity change by migraine phase? A blinded longitudinal study
Hagen, Knut; Omland, Petter Moe; Stovner, Lars Jacob; Sand, Trond Halfdan; Uglem, Martin; Tronvik, Erling Andreas; Nilsen, Kristian Bernhard; Linde, Anders Mattias (Journal article; Peer reviewed, 2016)Objective: Studies suggest that pain thresholds may be altered before and during migraine headaches, but it is still debated if a central or peripheral dysfunction is responsible for the onset of pain in migraine. The ... -
Genome-wide analysis identifies impaired axonogenesis in chronic overlapping pain conditions
Khoury, Samar; Parisien, Marc; Thompson, Scott J.; Vachon-Presseau, Etienne; Roy, Mathieu; Mitchell, Amy; Winsvold, Bendik K S; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J.; Fors, Egil Andreas; Heuch, Ingrid; Nielsen, Jonas Bille; Storheim, Kjersti; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Mundal, Ingunn Pernille; Zwart, John Anker Henrik; Kania, Artur; Mogil, Jeffrey S.; Diatchenko, Luda (Peer reviewed; Journal article, 2021)Chronic pain is often present at more than one anatomical location, leading to chronic overlapping pain conditions (COPC). Whether COPC represents a distinct pathophysiology from the occurrence of pain at only one site is ...