Browsing NTNU Open by Author "Gundersen, Morten Andre"
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Lipase Catalyzed Synthesis of Enantiopure Precursors and Derivatives for β-Blockers Practolol, Pindolol and Carteolol
Gundersen, Morten Andre; Austli, Guro Buaas; Løvland, Sigrid Sløgedal; Hansen, Mari Bergan; Rødseth, Mari; Jacobsen, Elisabeth Egholm (Peer reviewed; Journal article, 2021)Sustainable methods for producing enantiopure drugs have been developed. Chlorohydrins as building blocks for several β-blockers have been synthesized in high enantiomeric purity by chemo-enzymatic methods. The yield of ...