Browsing NTNU Open by Author "Giskeødegård, Guro F."
Now showing items 1-20 of 65
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ALASCA: An R package for longitudinal and cross-sectional analysis of multivariate data by ASCA-based methods
Jarmund, Anders Hagen; Madssen, Torfinn Støve; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2022) -
Assessing treatment response and prognosis by serum and tissue metabolomics in breast cancer patients
Debik, Julia Barbara; Euceda, Leslie R.; Lundgren, Steinar; Gythfeldt, Hedda; Garred, Øystein; Borgen, Elin; Engebråten, Olav; Bathen, Tone Frost; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2019)Patients with locally advanced breast cancer have a worse prognosis compared to patients with localized tumors and require neoadjuvant treatment before surgery. The aim of this study was to characterize the systemic metabolic ... -
The association between circulating lipoprotein subfractions and lipid content in coronary atheromatous plaques assessed by near-infrared spectroscopy
Sæther, Julie Caroline; Vesterbekkmo, Elisabeth Kleivhaug; Gigante, Bruna; Giskeødegård, Guro F.; Bathen, Tone Frost; Follestad, Turid; Wiseth, Rune; Madssen, Erik; Bye, Anja (Peer reviewed; Journal article, 2023)Background Lipid content in coronary atheromatous plaques, measured by near-infrared spectroscopy (NIRS), can predict the risk of future coronary events. Biomarkers that reflect lipid content in coronary plaques may ... -
Association of serum cortisol and cortisone levels and risk of recurrence after endocrine treatment in breast cancer
Wang, Feng; Giskeødegård, Guro F.; Skarra, Sissel; Engstrøm, Monica Jernberg; Hagen, Lars; Geisler, Jürgen; Mikkola, Tomi S.; Tikkanen, Matti J.; Debik, Julia; Reidunsdatter, Randi Johansen; Bathen, Tone Frost (Peer reviewed; Journal article, 2023)Metabolic reprogramming in breast cancer involves changes in steroid hormone synthesis and metabolism. Alterations in estrogen levels in both breast tissue and blood may influence carcinogenesis, breast cancer growth, and ... -
Atherogenic lipidomics profile in healthy individuals with low cardiorespiratory fitness: The HUNT3 fitness study
Nodeland, Markus; Klevjer, Marie; Sæther, Julie Caroline; Giskeødegård, Guro F.; Bathen, Tone Frost; Wisløff, Ulrik; Bye, Anja (Journal article; Peer reviewed, 2022) -
Automated segmentation of tumors in dynamic contrast-enhanced MRI of high-risk breast cancer patients undergoing neoadjuvant therapy
Tafavvoghi, Masoud (Master thesis, 2021)Brystkreft er den vanligste kreft blant kvinner, med nesten 3700 nye tilfeller diagnostisert årlig i Norge. Innenfor denne gruppen diagnostiseres mellom 5 og 10% på stadium III med lokalavansert brystkreft. Presurgical ... -
Biomarker discovery using NMR based metabolomics of tissue
Grinde, Maria Tunset; Giskeødegård, Guro F.; Andreassen, Trygve; Tessem, May-Britt; Bathen, Tone Frost; Moestue, Siver Andreas (Journal article; Peer reviewed, 2019)NMR-based metabolomics has shown promise in the diagnosis of diseases as it enables identification and quantification of metabolic biomarkers. Using high-resolution magic-angle-spinning (HR-MAS) NMR spectroscopy, metabolic ... -
Changes to intermediary metabolites in sporadic and LRRK2 Parkinson's disease demonstrated by proton magnetic resonance spectroscopy
Aasly, Jan; Sæther, Oddbjørn; Johansen, Krisztina Kunszt; Bathen, Tone Frost; Giskeødegård, Guro F.; White, Linda (Peer reviewed; Journal article, 2015)Background. Parkinson’s disease (PD) remains a clinical diagnosis and biomarkers are needed to detect the disease as early as possible. Genetically determined PD provides an opportunity for studying metabolic differences ... -
Colorectal cancer detected by liquid biopsy 2 years prior to clinical diagnosis in the HUNT study
Brenne, Siv Stakset; Madsen, Poul Henning; Pedersen, Inge Søkilde; Hveem, Kristian; Skorpen, Frank; Krarup, Henrik Bygum; Giskeødegård, Guro F.; Laugsand, Eivor Alette (Peer reviewed; Journal article, 2023) -
Combined 18F-Fluciclovine PET/MRI shows potential for detection and characterization of high-risk prostate cancer
Elschot, Mattijs; Selnæs, Kirsten Margrete; Sandsmark, Elise; Krüger-Stokke, Brage; Størkersen, Øystein; Giskeødegård, Guro F.; Tessem, May-Britt; Moestue, Siver Andreas; Bertilsson, Helena; Bathen, Tone Frost (Journal article; Peer reviewed, 2017)The objective of this study is to investigate if quantitative imaging features derived from combined 18F-Fluciclovine Positron Emission Tomograpy (PET) / multiparametric Magnetic Resonance Imaging (MRI) show potential for ... -
A comparison of FDG PET/MR and PET/CT for staging, response assessment, and prognostic imaging biomarkers in lymphoma
Husby, Trine; Johansen, Håkon; Bogsrud, Trond; Hustad, Kari Vekseth; Evensen, Birte Veslemøy; Boellard, Ronald; Giskeødegård, Guro F.; Fagerli, Unn-Merete; Eikenes, Live (Peer reviewed; Journal article, 2022)The aim of the current study was to investigate the diagnostic performance of FDG PET/MR compared to PET/CT in a patient cohort including Hodgkins lymphoma, diffuse large B-cell lymphoma, and high-grade B-cell lymphoma at ... -
Cytokine Patterns in Maternal Serum From First Trimester to Term and Beyond
Jarmund, Anders Hagen; Giskeødegård, Guro F.; Ryssdal, Mariell; Steinkjer, Bjørg; Stokkeland, Live Marie; Madssen, Torfinn Støve; Stafne, Signe Nilssen; Stridsklev, Solhild; Moholdt, Trine; Heimstad, Runa Kristine; Vanky, Eszter; Iversen, Ann-Charlotte (Peer reviewed; Journal article, 2021)Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity and fetal demands. We performed cytokine profiling of 1149 longitudinal serum ... -
Cytokine profiling as a measure of immunological development and deviation throughout pregnancy in healthy women and women with PCOS
Stokkeland, Live Marie Tobiesen (Doctoral theses at NTNU;2022:183, Doctoral thesis, 2022)Norsk sammendrag Cytokinprofilering som mål på immunologiske forandringer gjennom svangerskapet hos friske kvinner og kvinner med PCOS Mors immunsystem tilpasser seg gjennom de ulike fasene av svangerskapet for å sikre ... -
Diagnostic accuracy of anti-3-[18F]-FACBC PET/MRI in gliomas
Karlberg, Anna Maria; Pedersen, Lars Kjelsberg; Vindstad, Benedikte Emilie; Skjulsvik, Anne Jarstein; Johansen, Håkon; Solheim, Ole Skeidsvoll; Skogen, Karoline; Kvistad, Kjell Arne; Bogsrud, Trond; Myrmel, Kristin Smistad; Giskeødegård, Guro F.; Ingebrigtsen, Tor; Berntsen, Erik Magnus; Eikenes, Live (Peer reviewed; Journal article, 2023)Purpose - The primary aim was to evaluate whether anti-3-[18F]FACBC PET combined with conventional MRI correlated better with histomolecular diagnosis (reference standard) than MRI alone in glioma diagnostics. The ability ... -
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation
Giskeødegård, Guro F.; Davies, Sarah K; Revell, Victoria L; Keun, Hector C.; Skene, Debra J (Peer reviewed; Journal article, 2015)Understanding how metabolite levels change over the 24 hour day is of crucial importance for clinical and epidemiological studies. Additionally, the association between sleep deprivation and metabolic disorders such as ... -
DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival
Pedersen, Christine Aaserød; Cao, Maria Dung; Fleischer, Thomas; Rye, Morten Beck; Knappskog, Stian; Eikesdal, Hans Petter; Lønning, Per Eystein; Tost, Jörg; Kristensen, Vessela N.; Tessem, May-Britt; Giskeødegård, Guro F.; Bathen, Tone Frost (Peer reviewed; Journal article, 2022)Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently not possible to accurately predict who will benefit from the ... -
Effect of Delayed Centrifugation on the Levels of NMR-Measured Lipoproteins and Metabolites in Plasma and Serum Samples
Debik, Julia; Isaksen, Sylvia Hetlelid; Strømmen, Magnus; Spraul, Manfred; Schäfer, Hartmut; Bathen, Tone Frost; Giskeødegård, Guro F. (Peer reviewed; Journal article, 2022)Metabolic profiling is widely used for large-scale association studies, based on biobank material. The main obstacle to the translation of metabolomic findings into clinical application is the lack of standardization, ... -
Effect of high-fat diet and morning or evening exercise on lipoprotein subfraction profiles: secondary analysis of a randomised trial
Moholdt, Trine; Parr, Evelyn B.; Devlin, Brooke L.; Giskeødegård, Guro F.; Hawley, John A. (Journal article; Peer reviewed, 2023) -
Effect of Repeated Freeze‒Thaw Cycles on NMR-Measured Lipoproteins and Metabolites in Biofluids
Wang, Feng; Debik, Julia; Andreassen, Trygve; Euceda, Leslie R.; Haukaas, Tonje Husby; Cannet, Claire; Schäfer, Hartmut; Bathen, Tone Frost; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2019)Metabolic profiling of biofluids by nuclear magnetic resonance (NMR) spectroscopy serves as an important tool in disease characterization, and its accuracy largely depends on the quality of samples. We aimed to explore ... -
Establishing Methodology and Best Practices for Metagenomic and Metatranscriptomic Study of the Human Gut Microbiome
Desiati, Indri (Master thesis, 2022)Due to its fundamental impact on overall health, the gut microbiome has emerged as one of the most popular research subjects over the last decade. It is believed that there are associations between gut microbial perturbation ...