Browsing NTNU Open by Author "Drejer, Eivind Bøe"
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Establishment of a functional system for recombinant production of secreted proteins at 50 °C in the thermophilic Bacillus methanolicus
Irla, Marta Katarzyna; Drejer, Eivind Bøe; Brautaset, Trygve; Hakvåg, Sigrid (Peer reviewed; Journal article, 2020)Background The suitability of bacteria as microbial cell factories is dependent on several factors such as price of feedstock, product range, production yield and ease of downstream processing. The facultative methylotroph ... -
Genetic Tools and Techniques for Recombinant Expression in Thermophilic Bacillaceae
Drejer, Eivind Bøe; Hakvåg, Sigrid; Irla, Marta Katarzyna; Brautaset, Trygve (Journal article; Peer reviewed, 2018)Although Escherichia coli and Bacillus subtilis are the most prominent bacterial hosts for recombinant protein production by far, additional species are being explored as alternatives for production of difficult-to-express ... -
Metabolic engineering of Bacillus methanolicus for production of recombinant proteins and acetoin from methanol
Drejer, Eivind Bøe (Doctoral theses at NTNU;2020:339, Doctoral thesis, 2020)The use of methanol as a carbon source for industrial biotechnology is a tantalizing prospect. Methanol is highly abundant, and has a long history of efficient, large-scale production. It can be produced abiotically from ... -
Methanol-based acetoin production by genetically engineered Bacillus methanolicus
Drejer, Eivind Bøe; Chan, Dennis; Haupka, Carsten; Wendisch, Volker F.; Brautaset, Trygve; Irla, Marta Katarzyna (Journal article; Peer reviewed, 2019)Methanol is an attractive alternative non-food feedstock for industrial fermentations that can be used instead of sugar-based raw materials. Here, the thermophilic and methylotrophic bacterium Bacillus methanolicus MGA3 ... -
Modelling and Analysis of Osmotic Stress in Escherichia Coli
Drejer, Eivind Bøe (Master thesis, 2015)Microorganisms are known to be affected by stresses such as osmotic stress by reducing their growth rate. Understanding the mechanisms behind this are important, as it can aid in the development of new methods of con- serving ...