• Association of serum cortisol and cortisone levels and risk of recurrence after endocrine treatment in breast cancer 

      Wang, Feng; Giskeødegård, Guro F.; Skarra, Sissel; Engstrøm, Monica Jernberg; Hagen, Lars; Geisler, Jürgen; Mikkola, Tomi S.; Tikkanen, Matti J.; Debik, Julia; Reidunsdatter, Randi Johansen; Bathen, Tone Frost (Peer reviewed; Journal article, 2023)
      Metabolic reprogramming in breast cancer involves changes in steroid hormone synthesis and metabolism. Alterations in estrogen levels in both breast tissue and blood may influence carcinogenesis, breast cancer growth, and ...
    • Effect of Delayed Centrifugation on the Levels of NMR-Measured Lipoproteins and Metabolites in Plasma and Serum Samples 

      Debik, Julia; Isaksen, Sylvia Hetlelid; Strømmen, Magnus; Spraul, Manfred; Schäfer, Hartmut; Bathen, Tone Frost; Giskeødegård, Guro F. (Peer reviewed; Journal article, 2022)
      Metabolic profiling is widely used for large-scale association studies, based on biobank material. The main obstacle to the translation of metabolomic findings into clinical application is the lack of standardization, ...
    • Effect of Repeated Freeze‒Thaw Cycles on NMR-Measured Lipoproteins and Metabolites in Biofluids 

      Wang, Feng; Debik, Julia; Andreassen, Trygve; Euceda, Leslie R.; Haukaas, Tonje Husby; Cannet, Claire; Schäfer, Hartmut; Bathen, Tone Frost; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2019)
      Metabolic profiling of biofluids by nuclear magnetic resonance (NMR) spectroscopy serves as an important tool in disease characterization, and its accuracy largely depends on the quality of samples. We aimed to explore ...
    • Lipoprotein and metabolite associations to breast cancer risk in the HUNT2 study 

      Debik, Julia; Schäfer, Hartmut; Andreassen, Trygve; Wang, Feng; Fang, Fang; Cannet, Claire; Spraul, Manfred; Bathen, Tone Frost; Giskeødegård, Guro F. (Peer reviewed; Journal article, 2022)
      Background The aim of this study was to gain an increased understanding of the aetiology of breast cancer, by investigating possible associations between serum lipoprotein subfractions and metabolites and the long-term ...
    • Serum levels of inflammation-related markers and metabolites predict response to neoadjuvant chemotherapy with and without bevacizumab in breast cancers 

      Nome, Marianne Eikhom; Euceda, Leslie R.; Jabeen, Shakila; Debik, Julia; Bathen, Tone Frost; Giskeødegård, Guro F.; Tasken, Kristin Austlid; Mælandsmo, Gunhild Mari; Halvorsen, Bente; Yndestad, Arne; Borgen, Elin; Garred, Øystein; Aukrust, Pål; Ueland, Thor; Engebraaten, Olav; Kristensen, Vessela N.; Tekpli, Xavier (Journal article; Peer reviewed, 2019)
      Angiogenesis is necessary for tumor growth and has been targeted in breast cancer; however, it is unclear which patients will respond and benefit from antiangiogenic therapy. We report noninvasive monitoring of patient ...