Browsing NTNU Open by Author "Bye, Asta"
Now showing items 1-20 of 31
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A comparison of CT based measures of skeletal muscle mass and density from the Th4 and L3 levels in patients with advanced non-small-cell lung cancer
Grønberg, Bjørn Henning; Sjøblom, Bjørg; Wentzel-Larsen, Tore; Baracos, Vickie Elaine; Hjermstad, Marianne Jensen; Aass, Nina Kathrine; Bremnes, Roy M.; Fløtten, Øystein; Bye, Asta; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2018)Background: Muscle mass and density assessed from CT-images at the L3 level are prognostic for survival and predict toxicity in cancer patients. However, L3 is not always included on routine CT-scans. We aimed to investigate ... -
A randomized phase II feasibility trial of a multimodal intervention for the management of cachexia in lung and pancreatic cancer
Solheim, Tora Skeidsvoll; Laird, Barry J; Balstad, Trude Rakel; Stene, Guro Birgitte; Bye, Asta; Johns, Neil; Pettersen, Caroline Hild Hakvåg; Fallon, Marie; Fayers, Peter; Fearon, Kenneth; Kaasa, Stein (Journal article; Peer reviewed, 2017)Background: Cancer cachexia is a syndrome of weight loss (including muscle and fat), anorexia, and decreased physical function. It has been suggested that the optimal treatment for cachexia should be a multimodal intervention. ... -
Alterations in inflammatory biomarkers and energy intake in cancer cachexia: a prospective study in patients with inoperable pancreatic cancer
Bye, Asta; Wesseltoft-Rao, Nima; Iversen, Per Ole; Skjegstad, Grete S; Holven, Kirsten Bjørklund; Ulven, Stine Marie; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2016)Chronic systemic inflammatory response is proposed as an underlying mechanism for development of cancer cachexia. We conducted a prospective study to examine changes in inflammatory biomarkers during the disease course and ... -
Appetite and dietary intake endpoints in cancer cachexia clinical trials: Systematic Review 2 of the cachexia endpoints series
Vagnildhaug, Ola Magne; Balstad, Trude Rakel; Ottestad, Inger; Bye, Asta; Greil, Christine; Arends, Jann; Baracos, Vickie; Brown, Leo R.; Dajani, Olav; Dolan, Ross D.; Fallon, Marie; Fraser, Eilidh; Grzyb, Aleksandra; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Kaasa, Stein; McDonald, James; Philips, Iain; Sayers, Judith; Simpson, Melanie Rae; Sousa, Mariana S.; Skipworth, Richard J.E.; Laird, Barry J.A.; Solheim, Tora S (Journal article; Peer reviewed, 2024)There is no consensus on the optimal endpoint(s) in cancer cachexia trials. Endpoint variation is an obstacle when comparing interventions and their clinical value. The aim of this systematic review was to summarize and ... -
The association between age and long-term quality of life after curative treatment for prostate cancer: a cross-sectional study
Sletten, Reidun; Christiansen, Ola B.; Oldervoll, Line Merethe; Åstrøm, Lennart; Skjellegrind, Håvard Kjesbu; Saltyte Benth, Jurate; Kirkevold, Øyvind; Bergh, Sverre; Grønberg, Bjørn Henning; Rostoft, Siri; Bye, Asta; Mork, Paul Jarle; Slaaen, Marit (Journal article; Peer reviewed, 2024)Objective: We aimed to investigate the associations between age at radical prostate cancer treatment and long-term global quality of life (QoL), physical function (PF), and treatment-related side effects. Material and ... -
Benefits of Study Participation for Patients with Advanced Cancer Receiving Radiotherapy: A Prospective Observational Study
Bye, Asta; Bjerkeset, Ellen; Stensheim, Hanne; Loge, Jon Håvard; Hjermstad, Marianne Jensen; Klepstad, Pål; Habberstad, Ragnhild H; Kaasa, Stein; Aass, Nina Kathrine (Peer reviewed; Journal article, 2022)Background: Patients with advanced cancer and bone metastases may have unmet palliative care (PC) needs that go unnoticed during clinical oncological practice. This observational study describes interventions that were ... -
Biomarker endpoints in cancer cachexia clinical trials: Systematic Review 5 of the cachexia endpoint series
Yule, Michael S.; Thompson, Joshua; Leesahatsawat, Khachonphat; Sousa, Mariana S.; Anker, Stefan D.; Arends, Jann; Balstad, Trude Rakel; Brown, Leo R.; Bye, Asta; Dajani, Olav; Fallon, Marie; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; McDonald, James; McGovern, Josh; Roeland, Eric J.; Sayers, Judith; Skipworth, Richard J.E.; Ottestad, Inger; Philips, Iain; Simpson, Melanie Rae; Solheim, Tora S; Vagnildhaug, Ola Magne; McMillan, Donald; Laird, Barry J; Dolan, Ross D. (Journal article; Peer reviewed, 2024)Regulatory agencies require evidence that endpoints correlate with clinical benefit before they can be used to approve drugs. Biomarkers are often considered surrogate endpoints. In cancer cachexia trials, the measurement ... -
Body weight and composition endpoints in cancer cachexia clinical trials: Systematic Review 4 of the cachexia endpoints series
Brown, Leo R.; Sousa, Mariana S.; Yule, Michael S.; Baracos, Vickie E.; McMillan, Donald C.; Arends, Jann; Balstad, Trude Rakel; Bye, Asta; Dajani, Olav; Dolan, Ross D.; Fallon, Marie T.; Greil, Christine; Hjermstad, Marianne Jensen; Jakobsen, Gunnhild; Maddocks, Matthew; McDonald, James; Ottestad, Inger; Phillips, Iain; Sayers, Judith; Simpson, Melanie Rae; Vagnildhaug, Ola Magne; Solheim, Tora S; Laird, Barry J; Skipworth, Richard J.E. (Journal article; Peer reviewed, 2024)Significant variation exists in the outcomes used in cancer cachexia trials, including measures of body composition, which are often selected as primary or secondary endpoints. To date, there has been no review of the most ... -
Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial
Solheim, Tora Skeidsvoll; Laird, Barry J. A.; Balstad, Trude Rakel; Bye, Asta; Stene, Guro Birgitte; Baracos, Vickie; Strasser, Florian; Griffiths, Gareth; Maddocks, Matthew; Fallon, Marie; Kaasa, Stein; Fearon, Kenneth (Journal article; Peer reviewed, 2018)Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a ... -
Comparing two Classifications of Cancer Cachexia and Their Association with Survival in Patients with Unresected Pancreatic Cancer
Wesseltoft-Rao, Nima; Hjermstad, Marianne Jensen; Andersen, Tone Ikdahl; Dajani, Olav; Ulven, Stine Marie; Iversen, Per Ole; Bye, Asta (Journal article; Peer reviewed, 2015)There is no universally accepted definition of cancer cachexia. Two classifications have been proposed; the 3-factor classification requiring ≥2 of 3 factors; weight loss ≥10%, food intake ≤1500 kcal/day, and C-reactive ... -
Correction to: Norwegian reference values for the Short-Form Health Survey 36: development over time
Jacobsen, Ellisiv Lærum; Bye, Asta; Aass, Nina Kathrine; Fosså, Sophie Dorothea; Grotmol, Kjersti Støen; Kaasa, Stein; Loge, Jon Håvard; Moum, Torbjørn Åge; Hjermstad, Marianne Jensen (Journal article; Peer reviewed, 2017) -
Deterioration in Muscle Mass and Physical Function Differs According to Weight loss History in Cancer Cachexia
Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2019)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ... -
Dietary treatment of weight loss in patients with advanced cancer and cachexia: A systematic literature review
Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Strasser, Florian; Kaasa, Stein; Bye, Asta (Journal article; Peer reviewed, 2014)Purpose: A systematical literature review evaluating the effect of dietary counseling in treating weight loss and improving energy intake in patients with advanced cancer with different stages of cachexia. Principal ... -
Exercise and nutrition interventions in patients with head and neck cancer during curative treatment: A systematic review and meta-analysis
Bye, Asta; Sandmæl, Jon Arne; Stene, Guro Birgitte; Thorsen, Lene; Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Pripp, Are Hugo; Oldervoll, Line Merethe (Peer reviewed; Journal article, 2020)The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck ... -
Food intake by Patient-Generated Subjective Global Assessment (PG-SGA) corresponds to energy and protein intake as well as weight change in patients with advanced cancer
Bye, Asta; Meli, Kari; Solheim, Tora Skeidsvoll; Laird, Barry J; Kaasa, Stein; Stene, Guro Birgitte; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)Background & aims The aim of this study was to test how well the Patient-Generated Subjective Global Assessment (PG-SGA) question about food intake correlates with a well-established measurement of food intake. Furthermore, ... -
Geriatric assessment with management for older patients with cancer receiving radiotherapy. Protocol of a Norwegian cluster-randomised controlled pilot study
Røyset, Inga Marie; Saltvedt, Ingvild; Rostoft, Siri; Grønberg, Bjørn Henning; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Saltyte Benth, Jurate; Bergh, Sverre; Melby, Line; Halsteinli, Vidar; Døhl, Øystein; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2021)About 50% of patients with cancer are expected to need radiotherapy (RT), and the majority of these are older. To improve outcomes for older patients with cancer, geriatric assessment (GA) with management (GAM) is highly ... -
Geriatric assessment with management for older patients with cancer receiving radiotherapy: a cluster-randomised controlled pilot study
Jordhøy, Marit Slaaen; Røyset, Inga Marie; Saltvedt, Ingvild Tina; Grønberg, Bjørn Henning; Halsteinli, Vidar; Døhl, Øystein; Vossius, Corinna Elisabeth; Kirkevold, Øyvind; Bergh, Sverre; Rostoft, Siri; Oldervoll, Line Merethe; Bye, Asta; Melby, Line Kari; Røsstad, Tove Garåsen; Eriksen, Guro Falk; Sollid, May Ingvild Volungholen; Rolfson, Darryl; Saltyte Benth, Jurate (Journal article; Peer reviewed, 2024)Background: Geriatric assessment and management (GAM) improve outcomes in older patients with cancer treated with surgery or chemotherapy. It is unclear whether GAM may provide better function and quality of life (QoL), ... -
Geriatric impairments are associated with reduced quality of life and physical function in older patients with cancer receiving radiotherapy - A prospective observational study
Eriksen, Guro Falk; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Kirkhus, Lene; Kirkevold, Øyvind; Oldervoll, Line Merethe; Bye, Asta; Hjelstuen, Anne Kristine; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2022)Introduction: Quality of life (QoL) and function are important outcomes for older adults with cancer. We aimed to assess differences in trends in patient-reported outcomes (PROs) during radiotherapy (RT) between (1) groups ... -
Low fat, low lactose diet used as prophylactic treatment of acute intestinal reactions during pelvic radiotherapy. A prospective randomised study
Bye, Asta (Dissertations at the Faculty of Medicine, 0805-7680; 203, Doctoral thesis, 2002)Purpose. The main aim of the present study was to evaluate the effect of a low fat, low lactose diet on acute and late gastrointestinal side effects of pelvic radiotherapy. We also wanted to evaluate if such a treatment ... -
Measurements of body fat is associated with markers of inflammation, insulin resistance and lipid levels in both overweight and in lean, healthy subjects
Rao, Nima; Holven, Kirsten Bjørklund; Telle, Vibeke Helen; Narverud, Ingunn; Iversen, Per Ole; Hjermstad, Marianne Jensen; Dahlman, Ingrid; Ulven, Stine Marie; Bye, Asta (Journal article; Peer reviewed, 2012)