• The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure 

      Shahini, Negar; Bjørkelund, Elisabeth; Bendz, Christina; Massey, Richard J; Schjalm, Camilla; Halvorsen, Bente; Broch, Kaspar; Ueland, Thor; Gullestad, Lars; Nilsson, Per H.; Aukrust, Pål; Mollnes, Tom Eirik; Louwe, Maria Cornelia (Journal article; Peer reviewed, 2021)
      Objective Dysregulation of the complement system has been described in patients with heart failure (HF). However, data on the alternative pathway are scarce and it is unknown if levels of factor B (FB) and the C3 convertase ...
    • A clinical evaluation of a low-cost strain gauge respiration belt and machine learning to detect sleep apnea 

      Kristiansen, Stein; Nikolaidis, Konstantinos; Plagemann, Thomas Peter; Goebel, Vera Hermine; Traaen, Gunn Marit; Øverland, Britt; Akerøy, Lars; Hunt, Tove Elizabeth Frances; Loennechen, Jan Pål; Steinshamn, Sigurd Loe; Bendz, Christina; Anfinsen, Ole-Gunnar; Gullestad, Lars; Akre, Harriet (Peer reviewed; Journal article, 2023)
      Sleep apnea is a common and severe sleep-related respiratory disorder. Since the symptoms of sleep apnea are often ambiguous, it is difficult for a physician to decide whether to prescribe a clinical diagnosis, i.e., ...
    • Comparing manual and automatic scoring of sleep monitoring data from portable polygraphy 

      Kristiansen, Stein; Traaen, Gunn Marit; Øverland, Britt; Plagemann, Thomas Peter; Gullestad, Lars; Akre, Harriet; Nikolaidis, Konstantinos; Aakerøy, Lars; Hunt, Tove Elizabeth Frances; Loennechen, Jan Pål; Steinshamn, Sigurd Loe; Bendz, Christina; Anfinsen, Ole-Gunnar; Goebel, Vera Hermine (Journal article; Peer reviewed, 2020)
      We used sleep monitoring data from a study that investigated the prevalence, characteristics, risk factors and type of sleep apnea (SA) in 579 patients with paroxysmal atrial fibrillation. Most patients were screened for ...
    • Effect of continuous positive airway pressure therapy on recurrence of atrial fibrillation after pulmonary vein isolation in patients with obstructive sleep apnea: A randomized controlled trial 

      Hunt, Tove Elizabeth Frances; Traaen, Gunn Marit; Aakerøy, Lars; Bendz, Christina; Øverland, Britt; Akre, Harriet; Steinshamn, Sigurd Loe; Loennechen, Jan Pål; Hegbom, Finn; Broch, Kaspar; Lie, Øyvind Haugen; Lyseggen, Erik; Haugaa, Kristina Ingrid Helena Hermann; Gullestad, Lars; Anfinsen, Ole-Gunnar (Peer reviewed; Journal article, 2022)
      Background Obstructive sleep apnea (OSA) is associated with atrial fibrillation (AF). Whether treatment with continuous positive airway pressure (CPAP) reduces AF recurrence after catheter ablation with pulmonary vein ...
    • Interleukin-6 inhibition in ST-elevation myocardial infarction: Immune cell profile in the randomised ASSAIL-MI trial 

      Huse, Camilla; Anstensrud, Anne Kristine; Michelsen, Annika Elisabet; Ueland, Thor; Broch, Kaspar; Woxholt, Sindre; Yang, Kuan; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend Sturle; Bjørkelund, Elisabeth; Quiles-Jiménez, Ana M T; Bjerkeli, Vigdis; Bendz, Christina; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Andersen, Geir Øystein; Wiseth, Rune; Halvorsen, Bente; Gullestad, Lars; Seljeflot, Ingebjørg; Aukrust, Pål; Osnes, Liv T. N.; Dahl, Tuva Børresdatter (Peer reviewed; Journal article, 2022)
      We recently showed that interleukin (IL)-6 inhibition by tocilizumab improves myocardial salvage in ST-elevation myocardial infarction (STEMI). However, the mechanisms for this effect are not clear. Methods In this ...
    • Prevalence, risk factors, and type of sleep apnea in patients with paroxysmal atrial fibrillation 

      Traaen, Gunn Marit; Øverland, Britt; Aakerøy, Lars; Hunt, Tove Elizabeth Frances; Bendz, Christina; Leif Magne, Sande; Aakhus, Svend; Zare, Hasse Khiabani; Steinshamn, Sigurd Loe; Anfinsen, Ole-Gunnar; Loennechen, Jan Pål; Gullestad, Lars; Akre, Harriet (Peer reviewed; Journal article, 2019)
      Background Recent studies have suggested an association between sleep apnea (SA) and atrial fibrillation (AF). We aimed to study the prevalence, characteristics, risk factors and type of sleep apnea (SA) in ablation ...
    • Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction 

      Broch, Kaspar; Anstensrud, Anne Kristine; Woxholt, Sindre; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Aakhus, Svend; Ueland, Thor; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend; Bjørkelund, Elisabeth; Bendz, Christina; Hopp, Einar; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Seljeflot, Ingebjørg; Andersen, Geir Øystein; Wiseth, Rune; Aukrust, Pål; Gullestad, Lars (Journal article; Peer reviewed, 2021)
      Background - Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, as ...